The induction of chromosome aberrations by restriction endonucleases that produce blunt-end or cohesive-end double-strand breaks

Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles

1982 • 320 citations

Enzymatic Restriction of Mammalian Cell DNA Using Pvu II and Bam H1: Evidence for the Double-strand Break Origin of Chromosomal Aberrations

1984 • 313 citations

Molecular mechanisms involved in the production of chromosomal aberrations

1984 • 303 citations

Molecular mechanisms involved in the production of cromosomal aberrations II. Utilization of neurospora endonuclease for the study of aberration production by X-rays in G1 and G2 stages of the cell cycle

1980 • 280 citations

The Chinese hamster Alu-equivalent sequence: a conserved highly repetitious, interspersed deoxyribonucleic acid sequence in mammals has a structure suggestive of a transposable element.

1981 • 157 citations

The effect of cytosine arabinoside on the frequency of X-ray-induced chromosome aberrations in normal human leukocytes

1980 • 138 citations

A model for restriction fragment length distributions.

1983 • 76 citations

Statistical Interpretation of the Overdispersed Distribution of Radiation-Induced Dicentric Chromosome Aberrations at High LET

1981 • 73 citations

The chromosome-breaking activity of the restriction endonuclease Alu I in CHO cells is independent of the S-phase of the cell cycle

1985 • 69 citations

Chromosomal aberrations induced by restriction endonucleases

1985 • 63 citations

Chromosomal aberrations induced by the restriction endonuclease Alu I in chinese hamster ovary cells: influence of duration of treatment and potentiation by cytosine arabinoside

1985 • 33 citations

Influence of bromodeoxyuridine substitution of thymidine on sister-chromatid exchanges and chromosomal aberrations induced by restriction endonucleases

1986 • 24 citations