Human cytomegalovirus UL37 immediate-early regulatory proteins traffic through the secretory apparatus and to mitochondria

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

Signal Sequence Recognition and Protein Targeting to the Endoplasmic Reticulum Membrane

1994 • 821 citations

A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins.

1994 • 431 citations

A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2

1999 • 422 citations

NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation.

1989 • 340 citations

Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication

1993 • 240 citations

Formation and isomerization of disulfide bonds in proteins: Protein disulfide-isomerase

1984 • 216 citations

[18] In vivo labeling and analysis of human mitochondrial translation products

1996 • 210 citations

The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID

1992 • 195 citations

Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis

1993 • 142 citations

The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulation

1993 • 138 citations

Human cytomegalovirus US3 and UL36-38 immediate-early proteins regulate gene expression

1992 • 134 citations

An immediate early gene of human cytomegalovirus encodes a potential membrane glycoprotein

1988 • 123 citations

Involvement of mitochondrial contact sites in the subcellular compartmentalization of phospholipid biosynthetic enzymes.

1993 • 110 citations

TAF-like functions of human cytomegalovirus immediate-early proteins

1997 • 101 citations

Human cytomegalovirus UL36-38 and US3 immediate-early genes: temporally regulated expression of nuclear, cytoplasmic, and polysome-associated transcripts during infection

1991 • 89 citations

Expression of the human cytomegalovirus UL36–38 immediate early region during permissive infection

1991 • 88 citations

In Vivo Mitochondrial Import

1999 • 63 citations

Steady-State Plasma Membrane Expression of Human Cytomegalovirus gB Is Determined by the Phosphorylation State of Ser ₉₀₀

1998 • 51 citations

The human cytomegalovirus UL37 immediate-early regulatory protein is an integral membrane N-glycoprotein which traffics through the endoplasmic reticulum and Golgi apparatus

1996 • 48 citations

The human cytomegalovirus US3 immediate-early protein lacking the putative transmembrane domain regulates gene expression

1993 • 39 citations

The Acidic Domain of pUL37x1 and gpUL37 Plays a Key Role in Transactivation of HCMV DNA Replication Gene Promoter Constructions

1998 • 38 citations

An Introduction to Confocal Imaging

2003 • 26 citations

Human Cytomegalovirus US3 Gene Expression Is Regulated by a Complex Network of Positive and Negative Regulators

1999 • 19 citations

The Acidic Domain of the Human Cytomegalovirus UL37 Immediate Early Glycoprotein Is Dispensable for Its Transactivating Activity and Localization but Is Not for Its Synergism

1996 • 15 citations

Analysis of Cytomegalovirus Gene Expression by Transfection

2003 • 3 citations