NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

1985 • 1,155 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.

1988 • 830 citations

Trans -Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

1984 • 781 citations

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

1987 • 762 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor

1988 • 607 citations

The involvement of NF-κB in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

1989 • 494 citations

HTLV-I Tax Induces Cellular Proteins that Activate the κB Element in the IL-2 Receptor α Gene

1988 • 480 citations

Characterization of antigen receptor response elements within the interleukin-2 enhancer.

1988 • 451 citations

Cytomegalovirus infects human lymphocytes and monocytes: virus expression is restricted to immediate-early gene products.

1984 • 407 citations

Detection of Human Cytomegalovirus in Peripheral Blood Lymphocytes in a Natural Infection

1985 • 365 citations

Structural analysis of the major immediate early gene of human cytomegalovirus

1984 • 342 citations

Cellular Transcription Factors and Regulation of IL-2 Receptor Gene Expression by HTLV-I tax Gene Product

1988 • 327 citations

Double-stranded RNA activates binding of NF-kappa B to an inducible element in the human beta-interferon promoter.

1989 • 317 citations

Footprinting DNA-protein complexes in situ following gel retardation assays using 1,10-phenanthroline-copper ion: Escherichia coli RNA polymerase-lac promoter complexes

1987 • 312 citations

Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element

1989 • 311 citations

Temporal Patterns of Human Cytomegalovirus Transcription: Mapping the Viral RNAs Synthesized at Immediate Early, Early, and Late Times After Infection

1982 • 311 citations

Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter.

1988 • 308 citations

Promoter-regulatory region of the major immediate early gene of human cytomegalovirus.

1984 • 296 citations

Functional domains of adenovirus type 5 E1a proteins

1987 • 283 citations

Sequence of protein synthesis in cells infected by human cytomegalovirus: early and late virus-induced polypeptides

1978 • 271 citations

A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1.

1988 • 259 citations

The role of the κ enhancer and its binding factor NF-κB in the developmental regulation of κ gene transcription

1987 • 247 citations

Activation of the major immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus-specific trans-acting components

1985 • 245 citations

Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class I major histocompatibility gene.

1987 • 244 citations

trans-activation and autoregulation of gene expression by the immediate-early region 2 gene products of human cytomegalovirus

1988 • 237 citations

Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts

1985 • 229 citations

A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro

1985 • 196 citations

HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene

1988 • 171 citations

The structure of the major immediate early gene of human cytomegalovirus strain AD169

1985 • 170 citations

Protein counterparts of human and simian cytomegaloviruses

1983 • 167 citations

Characterization of Antigen Receptor Response Elements within the Interleukin-2 Enhancer

1988 • 143 citations

Hepatitis B virus X gene can transactivate heterologous viral sequences.

1989 • 137 citations

Nuclear factor 1 interacts with five DNA elements in the promoter region of the human cytomegalovirus major immediate early gene.

1986 • 137 citations

Multiple tandemly repeated binding sites for cellular nuclear factor 1 that surround the major immediate-early promoters of simian and human cytomegalovirus

1987 • 127 citations

A cis-acting element within the 5′ leader of a cytomegalovirus β transcript determines kinetic class

1986 • 125 citations

Binding of transcription factors and creation of a large nucleoprotein complex on the human cytomegalovirus enhancer.

1987 • 123 citations

A labile inhibitor blocks immunoglobulin kappa-light-chain-gene transcription in a pre-B leukemic cell line.

1986 • 109 citations

[56] RNA polymerase nascent product analysis

1980 • 104 citations

Binding of a Nuclear Factor to a Regulatory Sequence in the Promoter of the Mouse H-2K^b Class I Major Histocompatibility Gene

1987 • 101 citations

Expression of the acidic nuclear immediate-early protein (IE1) of human cytomegalovirus in stable cell lines and its preferential association with metaphase chromosomes

1989 • 99 citations

Replication of human cytomegalovirus in human peripheral blood T cells

1986 • 91 citations

Immediate early antigens in human cytomegalovirus infected cells

1977 • 76 citations

Adenovirus 5 early region 1A host range mutants hr3, hr4, and hr5 contain point mutations which generate single amino acid substitutions

1985 • 69 citations

T-cell-specific expression of interleukin 2: evidence for a negative regulatory site.

1988 • 57 citations

Human Cytomegalovirus Replicates in Primary Human Bone Marrow Cells

1986 • 50 citations

Specific interactions between transcription factors and the promoter-regulatory region of the human cytomegalovirus major immediate-early gene

1988 • 48 citations

Induction of Pre‐Early Nuclear Antigen(s) in HEL Cells Infected with Human Cytomegalovirus

1979 • 26 citations