RanGTP-Regulated Interactions of CRM1 with Nucleoporins and a Shuttling DEAD-Box Helicase

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

1997 • 2,062 citations

Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

1996 • 1,687 citations

A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

1997 • 1,221 citations

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1997 • 1,195 citations

Identification of a signal for rapid export of proteins from the nucleus

1995 • 1,186 citations

NUCLEOCYTOPLASMIC TRANSPORT: The Soluble Phase

1998 • 1,184 citations

Exportin 1 (Crm1p) Is an Essential Nuclear Export Factor

1997 • 1,144 citations

The HIV-1 Rev Activation Domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1995 • 1,127 citations

Functional Coherence of the Human Y Chromosome

1997 • 818 citations

THE HIV-1 REV PROTEIN

1998 • 716 citations

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

1997 • 654 citations

Identification of different roles for RanGDP and RanGTP in nuclear protein import.

1996 • 644 citations

The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus

1997 • 628 citations

Export of Importin α from the Nucleus Is Mediated by a Specific Nuclear Transport Factor

1997 • 613 citations

Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores.

1987 • 510 citations

A giant nucleopore protein that binds Ran/TC4

1995 • 492 citations

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

1997 • 480 citations

Nup358, a Cytoplasmically Exposed Nucleoporin with Peptide Repeats, Ran-GTP Binding Sites, Zinc Fingers, a Cyclophilin A Homologous Domain, and a Leucine-rich Region

1995 • 471 citations

SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex

1998 • 455 citations

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export

1997 • 435 citations

Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.

1987 • 428 citations

A Novel Class of RanGTP Binding Proteins

1997 • 427 citations

HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: Implications for HIV-1 latency

1991 • 422 citations

Identification of a tRNA-Specific Nuclear Export Receptor

1998 • 379 citations

Requirement of the DEAD-Box Protein Ded1p for Messenger RNA Translation

1997 • 363 citations

Nucleocytoplasmic Transport: The Last 200 Nanometers

1998 • 361 citations

Protein Sequence Requirements for Function of the Human T-Cell Leukemia Virus Type 1 Rex Nuclear Export Signal Delineated by a Novel In Vivo Randomization-Selection Assay

1996 • 356 citations

The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus

1998 • 336 citations

Interaction of the Nuclear GTP-Binding Protein Ran with Its Regulatory Proteins RCC1 and RanGAP1

1995 • 334 citations

Nuclear export of different classes of RNA is mediated by specific factors

1994 • 323 citations

The early development of Xenopus laevisby P. Hausen and M. Riebesell, Springer-Verlag, 1991. £78.50 (vii + 142 pages) ISBN 3 540 53740 6

1993 • 323 citations

Identification of a nuclear export receptor for tRNA

1998 • 286 citations

O-linked N-acetylglucosamine is attached to proteins of the nuclear pore. Evidence for cytoplasmic and nucleoplasmic glycoproteins.

1987 • 268 citations

RanBP1 is crucial for the release of RanGTP from importin β‐related nuclear transport factors

1997 • 250 citations

The human CAN protein, a putative oncogene productassociated with myeloid leukemogenesis, is a nuclear pore complex protein thatfaces the cytoplasm.

1994 • 238 citations

The Specificity of the CRM1-Rev Nuclear Export Signal Interaction Is Mediated by RanGTP

1998 • 221 citations

Transport of macromolecules between the nucleus and the cytoplasm.

1998 • 207 citations

Interactions and three-dimensional localization of a group of nuclear pore complex proteins.

1994 • 206 citations

Major Binding Sites for the Nuclear Import Receptor Are the Internal Nucleoporin Nup153 and the Adjacent Nuclear Filament Protein Tpr

1998 • 199 citations

Differential Mitotic Phosphorylation of Proteins of the Nuclear Pore Complex

1995 • 198 citations

Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2

1998 • 193 citations

Inhibition of Human Immunodeficiency Virus Rev and Human T-Cell Leukemia Virus Rex Function, but Not Mason-Pfizer Monkey Virus Constitutive Transport Element Activity, by a Mutant Human Nucleoporin Targeted to Crm1

1998 • 170 citations

Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis

1999 • 167 citations

The protein encoded by a murine male germ cell-specific transcript is a putative ATP-dependent RNA helicase

1989 • 166 citations

Ran-unassisted Nuclear Migration of a 97-kD Component of Nuclear Pore–targeting Complex

1997 • 160 citations

A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1.

1996 • 155 citations

Regulated Splicing of the Drosophila P Transposable Element Third Intron in Vitro: Somatic Repression

1990 • 149 citations

Disassembly of RanGTP-Karyopherin β Complex, an Intermediate in Nuclear Protein Import

1997 • 147 citations

The small nonstructural protein (NS2) of the parvovirus minute virus of mice is required for efficient DNA replication and infectious virus production in a cell-type-specific manner

1990 • 137 citations

Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA.

1992 • 128 citations

A suppressor of a yeast splicing mutation (prp8-l) encodes a putative ATP-dependent RNA helicase

1991 • 116 citations

Nuclear RNA export

1998 • 114 citations

Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis

1998 • 113 citations

Nup84, A Novel Nucleoporin That Is Associated With CAN/Nup214 on the Cytoplasmic Face of the Nuclear Pore Complex

1997 • 102 citations

Characterization of the Nuclear Export Signal of Human T-Cell Lymphotropic Virus Type 1 Rex Reveals that Nuclear Export Is Mediated by Position-Variable Hydrophobic Interactions

1996 • 96 citations

A Role for Nucleoporin FG Repeat Domains in Export of Human Immunodeficiency Virus Type 1 Rev Protein and RNA from the Nucleus

1996 • 90 citations

Functional Characterization of a Nup159p-containing Nuclear Pore Subcomplex

1998 • 90 citations

Nucleocytoplasmic transport and processing of small nuclear RNA precursors.

1990 • 90 citations

Nuclear pore complex assembly studied with a biochemical assay for annulate lamellae formation.

1995 • 85 citations

Interaction of cellular proteins with the leukemia specific fusion proteins DEK-CAN and SET-CAN and their normal counterpart, the nucleoporin CAN.

1996 • 85 citations

Alternate splicing in a parvoviral nonstructural gene links a common amino-terminal sequence to downstream domains which confer radically different localization and turnover characteristics

1990 • 84 citations

Functions of the GTPase Ran in RNA export from the nucleus

1998 • 80 citations

The Xenopus localized messenger RNA An3 may encode an ATP-dependent RNA helicase

1991 • 78 citations

Rev protein and its cellular partners

2000 • 72 citations

[17] Catalysis of guanine nucleotide exchange or Ran by RCC1 and stimulation of hydrolysis of Ran-bound GTP by Ran-GAP1

1995 • 64 citations

A suppressor of yeast spp81/ded1 mutations encodes a very similar putative ATP‐dependent RNA helicase

1991 • 61 citations

Two yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically oriented subcomplex

1998 • 59 citations

Inhibition of mRNA export in vertebrate cells by nuclear export signal conjugates

1997 • 54 citations

Visualizing nuclear export of different classes of RNA by electron microscopy.

1997 • 50 citations

Automatedde novo sequencing of proteins using the differential scanning technique

2001 • 46 citations

Tools for the production and purification of full-length, N- or C-terminal 32P-labeled protein, applied to HIV-1 Gag and Rev

1995 • 38 citations

Nucleocytoplasmic Transport and Processing of Small Nuclear RNA Precursors

1990 • 37 citations

An3 protein encoded by a localized maternal mRNA in Xenopus laevis is an ATPase with substrate-specific RNA helicase activity

1997 • 34 citations

The embryonic RNA helicase gene (ERH): a new member of the DEAD box family of RNA helicases

1995 • 25 citations

Changes in nuclear localization of An3, a RNA helicase, during oogenesis and embryogenesis in Xenopus laevis

1996 • 11 citations

Energy- and Temperature-Dependent In Vitro Export of RNA from Synthetic Nuclei

1997 • 10 citations

Changes in nuclear localization of An3, a RNA helicase, during oogenesis and embryogenesis inXenopus laevis

1996 • 9 citations