The small nonstructural protein (NS2) of the parvovirus minute virus of mice is required for efficient DNA replication and infectious virus production in a cell-type-specific manner

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

The Autonomously Replicating Parvoviruses of Vertebrates

1987 • 492 citations

The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity

1990 • 467 citations

Reciprocal productive and restrictive virus-cell interactions of immunosuppressive and prototype strains of minute virus of mice

1983 • 201 citations

In vitro resolution of covalently joined AAV chromosome ends

1990 • 163 citations

The genome of minute virus of mice, an autonomous parvovirus, encodes two overlapping transcription units

1983 • 154 citations

Nonstructural protein of parvoviruses B19 and minute virus of mice controls transcription

1990 • 151 citations

DNA sequence of the lymphotropic variant of minute virus of mice, MVM(i), and comparison with the DNA sequence of the fibrotropic prototype strain

1986 • 142 citations

Replication of adeno-associated virus in cells irradiated with UV light at 254 nm

1989 • 139 citations

trans-Activation of parvovirus P38 promoter by the 76K noncapsid protein

1985 • 131 citations

The NS-1 polypeptide of minute virus of mice is covalently attached to the 5' termini of duplex replicative-form DNA and progeny single strands

1988 • 124 citations

Organization of nonstructural genes of the autonomous parvovirus minute virus of mice

1986 • 122 citations

Somatic mutation as the basis for malignant transformation of BHK cells by chemical carcinogens

1976 • 120 citations

A genome-linked copy of the NS-1 polypeptide is located on the outside of infectious parvovirus particles

1989 • 120 citations

Characterization of the trans-activation-responsive element of the parvovirus H-1 P38 promoter

1987 • 109 citations

The autonomous parvovirus MVM encodes two nonstructural proteins in addition to its capsid polypeptides

1983 • 107 citations

A precise map of splice junctions in the mRNAs of minute virus of mice, an autonomous parvovirus

1986 • 106 citations

Minute Virus of Mice Non-structural Protein NS-1 Is Necessary and Sufficient for Trans-activation of the Viral P39 Promoter

1988 • 100 citations

NS-1 and NS-2 proteins may act synergistically in the cytopathogenicity of parvovirus MVMp

1990 • 93 citations

Alternate splicing in a parvoviral nonstructural gene links a common amino-terminal sequence to downstream domains which confer radically different localization and turnover characteristics

1990 • 84 citations

Amplified ribosomal RNA genes in a rat hepatoma cell line are enriched in 5-methylcytosine.

1981 • 80 citations

Three splicing patterns are used to excise the small intron common to all minute virus of mice RNAs

1986 • 78 citations

The two transcription units of the autonomous parvovirus minute virus of mice are transcribed in a temporal order

1988 • 72 citations

Generation and characterization of a temperature-sensitive mutation in the NS-1 gene of the autonomous parvovirus minute virus of mice

1988 • 62 citations

Parvovirus Gene Regulation

1987 • 57 citations

The minute virus of mice P39 transcription unit can encode both capsid proteins

1986 • 55 citations

Construction of a genetic switch for inducible trans-activation of gene expression in eucaryotic cells

1987 • 55 citations

Both excision and replication of cloned autonomous parvovirus DNA require the NS1 (rep) protein

1989 • 54 citations

Cloning of minute virus of mice cDNAs and preliminary analysis of individual viral proteins expressed in murine cells

1990 • 43 citations

Chemical carcinogens transform BHK cells by inducing a recessive mutation.

1982 • 31 citations

A cis downstream element participates in regulation of in vitro transcription initiation from the P38 promoter of minute virus of mice

1990 • 30 citations

Chemical Carcinogens Transform BHK Cells by Inducing a Recessive Mutation

1982 • 9 citations