Inhibition of mRNA export in vertebrate cells by nuclear export signal conjugates

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

1997 • 2,062 citations

Identification of a signal for rapid export of proteins from the nucleus

1995 • 1,186 citations

Exportin 1 (Crm1p) Is an Essential Nuclear Export Factor

1997 • 1,144 citations

The HIV-1 Rev Activation Domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1995 • 1,127 citations

Nucleocytoplasmic Transport

1996 • 1,071 citations

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1993 • 760 citations

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1989 • 742 citations

Export of Importin α from the Nucleus Is Mediated by a Specific Nuclear Transport Factor

1997 • 613 citations

Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores

1997 • 510 citations

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export

1997 • 435 citations

Monomethylated cap structures facilitate RNA export from the nucleus

1990 • 411 citations

Protein Sequence Requirements for Function of the Human T-Cell Leukemia Virus Type 1 Rex Nuclear Export Signal Delineated by a Novel In Vivo Randomization-Selection Assay

1996 • 356 citations

Nuclear export of different classes of RNA is mediated by specific factors

1994 • 323 citations

Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins

1995 • 308 citations

The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm.

1994 • 305 citations

Nuclear Export Receptors: From Importin to Exportin

1997 • 282 citations

Mutational definition of the human immunodeficiency virus type 1 Rev activation domain

1991 • 276 citations

Role of nonhistone proteins in metaphase chromosome structure

1977 • 269 citations

A human nucleoporin-like protein that specifically interacts with HIV Rev

1995 • 268 citations

A Role for the M9 Transport Signal of hnRNP A1 in mRNA Nuclear Export

1997 • 249 citations

The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway

1997 • 236 citations

An RNA-export mediator with an essential nuclear export signal

1996 • 230 citations

Nuclear export signals and the fast track to the cytoplasm

1995 • 229 citations

The Vertebrate GLFG Nucleoporin, Nup98, Is an Essential Component of Multiple RNA Export Pathways

1997 • 227 citations

Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast

1995 • 223 citations

Targeting and function in mRNA export of nuclear pore complex protein Nup153.

1996 • 193 citations

The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export

1997 • 171 citations

A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1.

1996 • 155 citations

Reverse 5' caps in RNAs made in vitro by phage RNA polymerases.

1995 • 145 citations

Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport.

1991 • 144 citations

Importin/karyopherin protein family members required for mRNA export from the nucleus

1997 • 138 citations

G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214.

1996 • 133 citations

Yeast heat shock mRNAs are exported through a distinct pathway defined by Rip1p

1997 • 131 citations

Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA.

1992 • 128 citations

Identification oftrans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells

1990 • 128 citations

Nuclear transport of human immunodeficiency virus type 1, visna virus, and equine infectious anemia virus Rev proteins: identification of a family of transferable nuclear export signals

1996 • 119 citations

Retention and 5′ Cap Trimethylation of U3 snRNA in the Nucleus

1994 • 108 citations

HIV Rev uses a conserved cellular protein export pathway for the nucleocytoplasmic transport of viral RNAs

1996 • 106 citations

Multiple pathways in nuclear transport: the import of U2 snRNP occurs by a novel kinetic pathway.

1991 • 105 citations

Characterization of the Nuclear Export Signal of Human T-Cell Lymphotropic Virus Type 1 Rex Reveals that Nuclear Export Is Mediated by Position-Variable Hydrophobic Interactions

1996 • 96 citations

A Role for Nucleoporin FG Repeat Domains in Export of Human Immunodeficiency Virus Type 1 Rev Protein and RNA from the Nucleus

1996 • 90 citations

A Nuclear Export Signal in Kap95p Is Required for Both Recycling the Import Factor and Interaction with the Nucleoporin GLFG Repeat Regions of Nup116p and Nup100p

1997 • 84 citations

Multiple cis-acting signals for export of pre-U1 snRNA from the nucleus.

1993 • 67 citations

In vivo selection of RNAs that localize in the nucleus

1997 • 64 citations

Mutations in the Nuclear Export Signal of Human Ran-binding Protein RanBP1 Block the Rev-mediated Posttranscriptional Regulation of Human Immunodeficiency Virus Type 1

1997 • 62 citations

Nonaqueous isolation of transcriptionally active nuclei from Xenopus oocytes

1990 • 57 citations

Coupling of nuclear RNA export and protein import in vertebrate cells

1997 • 9 citations