Histone Hyperacetylation Is Associated with Amelioration of Experimental Colitis in Mice

A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease

1997 • 3,152 citations

Inflammatory bowel disease: Etiology and pathogenesis

1998 • 2,095 citations

Clinicopathologic study of dextran sulfate sodium experimental acute colitis

1998 • 1,955 citations

Histone deacetylases and cancer: causes and therapies

2001 • 1,833 citations

Antibodies to interleukin 12 abrogate established experimental colitis in mice.

1995 • 1,338 citations

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

2000 • 1,255 citations

Experimental models of inflammatory bowel disease

1995 • 1,215 citations

Histone deacetylase inhibitor selectively induces p21 ^WAF1 expression and gene-associated histone acetylation

2000 • 1,091 citations

Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn’s disease

2003 • 723 citations

Oxazolone Colitis, a Th2 Colitis Model Resembling Ulcerative Colitis, Is Mediated by IL-13-Producing NK-T Cells

2002 • 639 citations

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo.

2000 • 608 citations

Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway

2001 • 601 citations

Colorectal cancer prevention in ulcerative colitis: a case‐control study

2000 • 580 citations

The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines

2002 • 493 citations

Butyrate Inhibits NF-κB Activation in Lamina Propria Macrophages of Patients with Ulcerative Colitis

2002 • 429 citations

Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

1996 • 421 citations

IL-1β-converting enzyme (caspase-1) in intestinal inflammation

2001 • 408 citations

Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse

2003 • 385 citations

Memory and flexibility of cytokine gene expression as separable properties of human TH1 and TH2 lymphocytes

2002 • 353 citations

Role of covalent modifications of histones in regulating gene expression

1999 • 305 citations

Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production

2001 • 286 citations

Leptin: A pivotal mediator of intestinal inflammation in mice

2002 • 256 citations

Long-term therapy with sulphasalazine protects against colorectal cancer in ulcerative colitis: a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire

1996 • 241 citations

Macrophage-derived IL-18–mediated intestinal inflammation in the murine model of Crohn's disease

2001 • 196 citations

Regulation of T-cell apoptosis in inflammatory bowel disease: to die or not to die, that is the mucosal question

2001 • 183 citations

Modulation of Renal Disease in MRL/lpr Mice by Suberoylanilide Hydroxamic Acid

2004 • 144 citations

Treatment of T Cell-Dependent Experimental Colitis in SCID Mice by Local Administration of an Adenovirus Expressing IL-18 Antisense mRNA

2002 • 128 citations

Chronopharmacological Study of Valproic Acid in Mice: Comparison of oral and Rectal Administration.

1992 • 19 citations

Current patent status of histone deacetylase inhibitors

2002 • 15 citations

Deleted Work

1955 • 0 citations