Comparative genomics modeling of the NRSF/REST repressor network: From single conserved sites to genome-wide repertoire

The Human Genome Browser at UCSC

2002 • 9,920 citations

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

2005 • 4,706 citations

Combinatorial microRNA target predictions

2005 • 4,543 citations

Human MicroRNA Targets

2004 • 3,702 citations

A gene atlas of the mouse and human protein-encoding transcriptomes

2004 • 3,443 citations

The microRNA Registry

2003 • 2,203 citations

A pancreatic islet-specific microRNA regulates insulin secretion

2004 • 2,054 citations

The UCSC Genome Browser Database

2003 • 1,872 citations

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

2004 • 1,526 citations

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

2000 • 1,416 citations

Applied bioinformatics for the identification of regulatory elements

2004 • 1,210 citations

The Neuron-Restrictive Silencer Factor (NRSF): A Coordinate Repressor of Multiple Neuron-Specific Genes

1995 • 1,078 citations

REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons

1995 • 1,078 citations

Conversion of Xenopus Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein

1995 • 1,028 citations

REST and Its Corepressors Mediate Plasticity of Neuronal Gene Chromatin throughout Neurogenesis

2005 • 900 citations

Reciprocal actions of REST and a microRNA promote neuronal identity

2006 • 698 citations

In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes

2005 • 584 citations

neurogenins,a Novel Family ofatonal-Related bHLH Transcription Factors, Are Putative Mammalian Neuronal Determination Genes That Reveal Progenitor Cell Heterogeneity in the Developing CNS and PNS

1996 • 536 citations

Nova regulates brain-specific splicing to shape the synapse

2005 • 493 citations

CoREST: A functional corepressor required for regulation of neural-specific gene expression

1999 • 467 citations

An Experimental Approach

1957 • 463 citations

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

2004 • 460 citations

NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis

1998 • 454 citations

Corepressor-Dependent Silencing of Chromosomal Regions Encoding Neuronal Genes

2002 • 454 citations

A Small Modulatory dsRNA Specifies the Fate of Adult Neural Stem Cells

2004 • 440 citations

A common silencer element in the SCG10 and type II Na+ channel genes binds a factor present in nonneuronal cells but not in neuronal cells

1992 • 420 citations

Identification of potential target genes for the neuron-restrictive silencer factor.

1996 • 411 citations

Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes

1999 • 388 citations

Synaptic Transmission

2007 • 384 citations

New human and mouse microRNA genes found by homology search

2004 • 312 citations

Regulation of the Pancreatic Islet-Specific GeneBETA2 (neuroD) by Neurogenin 3

2000 • 278 citations

Human Chromosome 19 and Related Regions in Mouse: Conservative and Lineage-Specific Evolution

2001 • 216 citations

Small CTD Phosphatases Function in Silencing Neuronal Gene Expression

2005 • 214 citations

NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function

2003 • 207 citations

Control of Hippocampal Morphogenesis and Neuronal Differentiation by the LIM Homeobox Gene Lhx5

1999 • 169 citations

Expression of Neuronal Traits in Pancreatic Beta Cells

1997 • 163 citations

neuroD2 and neuroD3: Distinct Expression Patterns and Transcriptional Activation Potentials within the neuroD Gene Family

1996 • 160 citations

The Elegance of the MicroRNAs: A Neuronal Perspective

2005 • 158 citations

Quantitative Discrimination of MEF2 Sites

1996 • 112 citations

Intron-derived microRNAs—fine tuning of gene functions

2004 • 110 citations

Differential Expansion of Zinc-Finger Transcription Factor Loci in Homologous Human and Mouse Gene Clusters

2003 • 96 citations

A Broad Role for the Zinc Finger Protein ZNF202 in Human Lipid Metabolism

2000 • 92 citations

Biological Activity and Modular Structure of RE-1-silencing Transcription Factor (REST), a Repressor of Neuronal Genes

1998 • 89 citations

A clustering property of highly-degenerate transcription factor binding sites in the mammalian genome

2006 • 62 citations

A Conserved Role But Different Partners for the Transcriptional Corepressor CoREST in Fly and Mammalian Nervous System Formation

2004 • 57 citations

Intraspecies sequence comparisons for annotating genomes

2004 • 51 citations

A zinc finger protein that represses transcription of the human MHC class II gene, DPA.

1996 • 45 citations

The Transcriptional Repressor REST Determines the Cell-Specific Expression of the Human MAPK8IP1 Gene Encoding IB1 (JIP-1)

2001 • 43 citations

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2

2005 • 41 citations

Lineage-specific Expansion of KRAB Zinc-finger Transcription Factor Genes: Implications for the Evolution of Vertebrate Regulatory Networks

2003 • 37 citations

Two suppressors ofsel-12encode C2H2zinc-finger proteins that regulate presenilin transcription inCaenorhabditis elegans

2003 • 32 citations

Regulation of cholinergic gene expression by the neuron restrictive silencer factor/repressor element-1 silencing transcription factor

2003 • 22 citations

A mathematical and computational framework for quantitative comparison and integration of large-scale gene expression data

2005 • 16 citations