neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

1993 • 2,370 citations

Insulin-promoter-factor 1 is required for pancreas development in mice

1994 • 1,789 citations

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

1996 • 1,505 citations

Notch signalling controls pancreatic cell differentiation

1999 • 1,147 citations

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice

1997 • 1,011 citations

IPF1, a homeodomain-containing transactivator of the insulin gene.

1993 • 882 citations

Identification of neurogenin, a Vertebrate Neuronal Determination Gene

1996 • 821 citations

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

1997 • 779 citations

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

1997 • 776 citations

neurogenin1 Is Essential for the Determination of Neuronal Precursors for Proximal Cranial Sensory Ganglia

1998 • 731 citations

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

1997 • 690 citations

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β cells

1998 • 616 citations

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development.

1997 • 567 citations

The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice

1996 • 548 citations

neurogenins,a Novel Family ofatonal-Related bHLH Transcription Factors, Are Putative Mammalian Neuronal Determination Genes That Reveal Progenitor Cell Heterogeneity in the Developing CNS and PNS

1996 • 536 citations

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

1998 • 531 citations

An ultrastructural analysis of the developing embryonic pancreas

1972 • 495 citations

The bHLH Protein NEUROGENIN 2 Is a Determination Factor for Epibranchial Placode–Derived Sensory Neurons

1998 • 439 citations

Mash1 activates a cascade of bHLH regulators in olfactory neuron progenitors

1997 • 405 citations

Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9

1999 • 377 citations

Prox 1, a prospero-related homeobox gene expressed during mouse development

1993 • 371 citations

Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice

1999 • 351 citations

The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat

1991 • 338 citations

Restricted Expression of a Novel Murineatonal-Related bHLH Protein in Undifferentiated Neural Precursors

1996 • 252 citations

The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.

1996 • 234 citations

Expression of peptide YY in all four islet cell types in the developing mouse pancreas suggests a common peptide YY-producing progenitor

1994 • 189 citations

GENETIC CONTROL OF CELL FATE SPECIFICATION IN DROSOPHILA PERIPHERAL NERVOUS SYSTEM

1994 • 155 citations

Rat Endocrine Pancreatic Development in Relation to Two Homeobox Gene Products (Pdx-1 and Nkx 6.1)

1998 • 120 citations

The putative nuclear receptor mediator TIF1α is tightly associated with euchromatin

1999 • 95 citations

Neuronal cell fate specification in Drosophila

1994 • 86 citations

Development of pancreatic islets (review).

1999 • 72 citations

Relax, a novel rat bHLH transcriptional regulator transiently expressed in the ventricular proliferating zone of the developing central nervous system

1997 • 43 citations