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Chronic rejection in renal transplantation

Data up to Jan 2025

Published2003
Citations4
References206

Total Citations Per Year

Abstract

References (206)

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2000 • 500 citations

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1998 • 466 citations

Beneficial effects of treatment of early subclinical rejection

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1999 • 443 citations

Efficacy and safety of tacrolimus compared with ciclosporin microemulsion in renal transplantation: a randomised multicentre study

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2000 • 409 citations

MYCOPHENOLATE MOFETIL REDUCES LATE RENAL ALLOGRAFT LOSS INDEPENDENT OF ACUTE REJECTION

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1998 • 403 citations

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1998 • 371 citations

Chronic allograft nephropathy: An update

1999 • 367 citations

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1997 • 365 citations

ACUTE HUMORAL REJECTION IN RENAL ALLOGRAFT RECIPIENTS: I. INCIDENCE, SEROLOGY AND CLINICAL CHARACTERISTICS1

2001 • 357 citations

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2002 • 342 citations

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1995 • 336 citations

Chronic renal allograft rejection: Immunologic and nonimmunologic risk factors

1996 • 325 citations

All chronic rejection failures of kidney transplants were preceded by the development of HLA antibodies

2002 • 319 citations

Delayed graft function influences renal function, but not survival

2000 • 299 citations

Posttransplantation production of donor HLA-specific antibodies as a predictor of renal transplant outcome1

2003 • 298 citations

Arterial Hypertension and Renal Allograft Survival

2000 • 294 citations

INDIRECT ALLORECOGNITION OF MAJOR HISTOCOMPATIBILITY COMPLEX ALLOPEPTIDES IN HUMAN RENAL TRANSPLANT RECIPIENTS WITH CHRONIC GRAFT DYSFUNCTION1

1997 • 290 citations

INCIDENCE, DETERMINANTS, AND CONSEQUENCES OF SUBCLINICAL NONCOMPLIANCE WITH IMMUNOSUPPRESSIVE THERAPY IN RENAL TRANSPLANT RECIPIENTS

1995 • 288 citations

SIROLIMUS REDUCES THE INCIDENCE OF ACUTE REJECTION EPISODES DESPITE LOWER CYCLOSPORINE DOSES IN CAUCASIAN RECIPIENTS OF MISMATCHED PRIMARY RENAL ALLOGRAFTS: A PHASE II TRIAL1

1999 • 279 citations

Neointimal and Tubulointerstitial Infiltration by Recipient Mesenchymal Cells in Chronic Renal-Allograft Rejection

2001 • 275 citations

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1994 • 270 citations

Renal Transplantation in Black Americans

2000 • 269 citations

THE IMPACT OF ACUTE REJECTION EPISODES ON LONG-TERM GRAFT FUNCTION AND OUTCOME IN 1347 PRIMARY RENAL TRANSPLANTS TREATED BY 3 CYCLOSPORINE REGIMENS

1993 • 268 citations

EFFECT OF HISTOLOGICAL DAMAGE ON LONG-TERM KIDNEY TRANSPLANT OUTCOME

2001 • 264 citations

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1994 • 259 citations

Chronic renal transplant loss

1995 • 254 citations

VARIABLE ORAL ABSORPTION OF CYCLOSPORINE

1996 • 252 citations

Analysis of factors that affect outcome of primary cadaveric renal transplantation in the UK

1999 • 248 citations

Increased Immunogenicity and Cause of Graft Loss of Old Donor Kidneys

2001 • 247 citations

ANTIVIMENTIN ANTIBODIES ARE AN INDEPENDENT PREDICTOR OF TRANSPLANT-ASSOCIATED CORONARY ARTERY DISEASE AFTER CARDIAC TRANSPLANTATION1

2001 • 246 citations

Twelve Years' Experience with National Sharing of HLA-Matched Cadaveric Kidneys for Transplantation

2000 • 245 citations

HLAMatchmaker: a molecularly based algorithm for histocompatibility determination. I. Description of the algorithm

2002 • 245 citations

Contribution of direct and indirect recognition pathways to T cell alloreactivity.

1993 • 242 citations

A monoclonal antibody against GBM heparan sulfate induces an acute selective proteinuria in rats

1992 • 237 citations

Endothelial C4d deposition is associated with inferior kidney allograft outcome independently of cellular rejection

2001 • 234 citations

Delayed graft function of more than six days strongly decreases long-term survival of transplanted kidneys

1998 • 233 citations

The use of mycophenolate mofetil in transplant recipients

2000 • 233 citations

PROGNOSIS AFTER PRIMARY RENAL TRANSPLANT FAILURE AND THE BENEFICIAL EFFECTS OF REPEAT TRANSPLANTATION

1998 • 230 citations

C4d Deposition in Acute Rejection

2002 • 227 citations

The “injury response”: A concept linking nonspecific injury, acute rejection, and long-term transplant outcomes

1997 • 224 citations

Identification of the nonclassical HLA molecules, mica, as targets for humoral immunity associated with irreversible rejection of kidney allografts1

2002 • 205 citations

Chronic allograft nephropathy

2005 • 204 citations

THE RELATION BETWEEN ACUTE VASCULAR AND INTERSTITIAL RENAL ALLOGRAFT REJECTION AND SUBSEQUENT CHRONIC REJECTION

1995 • 204 citations

The renal risks of smoking

1997 • 201 citations

Humoral rejection in kidney transplantation: new concepts in diagnosis and treatment

2002 • 200 citations

Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shortening

2003 • 200 citations

Cadaver versus living donor kidneys: Impact of donor factors on antigen induction before transplantation

1999 • 182 citations

ASPIRIN, THROMBOSIS, AND THE FUTURE

1971 • 178 citations

Long-term impact of discontinued or reduced calcineurin inhibitor in patients with chronic allograft nephropathy

2001 • 177 citations

RISK FACTORS PREDICTING CHRONIC REJECTION OF RENAL ALLOGRAFTS

1994 • 175 citations

TRANSPLANT RENAL ARTERY STENOSIS IN 77 PATIENTS-DOES IT HAVE AN IMMUNOLOGICAL CAUSE?1

1996 • 161 citations

Morphological Spectrum of Polyoma Virus Disease in Renal Allografts: Diagnostic Accuracy of Urine Cytology

2001 • 158 citations

Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells

2003 • 157 citations

CONTROL OF ANTIDONOR ANTIBODY PRODUCTION WITH TACROLIMUS AND MYCOPHENOLATE MOFETIL IN RENAL ALLOGRAFT RECIPIENTS WITH CHRONIC REJECTION1

2001 • 156 citations

Kidney graft failure and presensitization against HLA Class I and Class II antigens1

2002 • 150 citations

EXCESS RISK OF RENAL ALLOGRAFT LOSS ASSOCIATED WITH CIGARETTE SMOKING

2001 • 148 citations

BIOPSY OF MARGINAL DONOR KIDNEYS: CORRELATION OF HISTOLOGIC FINDINGS WITH GRAFT DYSFUNCTION1

2000 • 148 citations

IMPACT OF ACUTE REJECTION AND EARLY ALLOGRAFT FUNCTION ON RENAL ALLOGRAFT SURVIVAL

1997 • 147 citations

Transplant glomerulopathy: Evolution of morphologically distinct changes

1985 • 146 citations

MEDICATION COMPLIANCE FOLLOWING RENAL TRANSPLANTATION

1999 • 145 citations

IMPACT OF DONOR-SPECIFIC ANTIBODIES ON CHRONIC REJECTION OCCURRENCE AND GRAFT LOSS IN RENAL TRANSPLANTATION: POSTTRANSPLANT ANALYSIS USING FLOW CYTOMETRIC TECHNIQUES1

2001 • 143 citations

Morphological Spectrum of Polyoma Virus Disease in Renal Allografts: Diagnostic Accuracy of Urine Cytology

2001 • 143 citations

Early versus late acute rejection episodes in renal transplantation

2003 • 140 citations

Enzyme-Linked Immunosorbent Spot Assay Analysis of Peripheral Blood Lymphocyte Reactivity to Donor HLA-DR Peptides

2002 • 137 citations

Detection of donor-specific anti-HLA antibodies with flow cytometry in eluates and sera from renal transplant recipients with chronic allograft nephropathy1

2003 • 133 citations

Immunologic risk factors and glomerular C4d deposits in chronic transplant glomerulopathy

2004 • 132 citations

Long‐Term Use of Mycophenolate Mofetil is Associated With a Reduction in the Incidence and Risk of Late Rejection

2003 • 125 citations

HYPERCHOLESTEROLEMIA IS ASSOCIATED WITH INCREASED KIDNEY GRAFT LOSS CAUSED BY CHRONIC REJECTION IN MALE PATIENTS WITH PREVIOUS ACUTE REJECTION

2000 • 121 citations

Association between specific HLA combinations and probability of kidney allograft loss: the taboo concept

1996 • 121 citations

Evolution of the Enzyme-Linked Immunosorbent Spot Assay for Post-Transplant Alloreactivity as a Potentially Useful Immune Monitoring Tool

2002 • 121 citations

DETERMINANTS OF CHRONIC RENAL ALLOGRAFT REJECTION IN CYCLOSPORINE-TREATED RECIPIENTS

1996 • 115 citations

Causes of late renal allograft loss: chronic allograft dysfunction, death, and other factors.

2001 • 111 citations

Increased expression of p16(INK4a) and p27(Kip1) cyclin-dependent kinase inhibitor genes in aging human kidney and chronic allograft nephropathy

2003 • 107 citations

THE VANISHING IMPORTANCE OF AGE IN RENAL TRANSPLANTATION

1999 • 107 citations

The Stability of the Glomerular Filtration Rate after Renal Transplantation Is Improving

2003 • 105 citations

Call for Revolution: A New Approach to Describing Allograft Deterioration

2002 • 105 citations

Impact of delayed graft function and acute rejection on graft survival

2002 • 102 citations

Why do we reject a graft? Role of indirect allorecognition in graft rejection

1999 • 100 citations

IS CHRONIC RENAL TRANSPLANT REJECTION A NON-IMMUNOLOGICAL PHENOMENON?

1986 • 100 citations

Replicative Senescence of Biliary Epithelial Cells Precedes Bile Duct Loss in Chronic Liver Allograft Rejection

2001 • 100 citations

Telomere Shortening and Cellular Senescence in a Model of Chronic Renal Allograft Rejection

2003 • 100 citations

Cell Senescence and Its Implications for Nephrology

2001 • 99 citations

Antibodies to basement membrane heparan sulfate proteoglycans bind to the laminae rarae of the glomerular basement membrane (GBM) and induce subepithelial GBM thickening.

1986 • 99 citations

DELAYED GRAFT FUNCTION DOES NOT REDUCE THE SURVIVAL OF RENAL TRANSPLANT ALLOGRAFTS

1998 • 98 citations

PROGRESSION OF KIDNEY DISEASE IN CHRONIC RENAL TRANSPLANT REJECTION

1991 • 98 citations

HLA MATCHMAKER: A MOLECULARLY BASED ALGORITHM FOR HISTOCOMPATIBILITY DETERMINATION

2003 • 97 citations

IMMUNOLOGIC FACTORS: THE MAJOR RISK FOR DECREASED LONG-TERM RENAL ALLOGRAFT SURVIVAL1,2

1999 • 96 citations

CHOLESTEROL AS AN INDEPENDENT PREDICTOR OF OUTCOME AFTER RENAL TRANSPLANTATION

2000 • 96 citations

Renal artery stenosis after kidney transplantation: Diagnostic and therapeutic approach

1998 • 93 citations

Peritubular Capillary Changes and C4d Deposits Are Associated with Transplant Glomerulopathy But Not IgA Nephropathy

2003 • 89 citations

Matching Older Kidneys with Older Patients Does Not Improve Allograft Survival

2002 • 89 citations

Glomerular Lesions in the Transplanted Kidney in Children

1987 • 88 citations

Delayed function reduces renal allograft survival independent of acute rejection

1996 • 86 citations

Peritubular capillaries in chronic renal allograft rejection: A quantitative ultrastructural study

2000 • 86 citations

Antibody Response Against Perlecan and Collagen Types IV and VI in Chronic Renal Allograft Rejection in the Rat

2002 • 84 citations

The nephrotoxicity of immunosuppressive drugs

1996 • 83 citations

OBSERVATIONS IN PATIENTS WITH A WELL‐TOLERATED HOMOTRANSPLANTED KIDNEY: POSSIBILITY OF A NEW SECONDARY DISEASE

1964 • 83 citations

VASCULAR ENDOTHELIAL GROWTH FACTOR EXPRESSION IN HUMAN CHRONIC RENAL ALLOGRAFT REJECTION1

1999 • 81 citations

Clinical correlation between renal allograft failure and hyperlipidemia.

1995 • 80 citations

The impact of late acute rejection after cadaveric kidney transplantation

2001 • 79 citations

HIGH INCIDENCE OF ANTITISSUE ANTIBODIES IN PATIENTS EXPERIENCING CHRONIC LIVER ALLOGRAFT REJECTION1

1998 • 78 citations

CLINICAL DETERMINANTS OF MULTIPLE ACUTE REJECTION EPISODES IN KIDNEY TRANSPLANT RECIPIENTS1

2000 • 77 citations

THE VARIABLE NATURE OF CHRONIC DECLINES IN RENAL ALLOGRAFT FUNCTION

1991 • 75 citations

An association between antibodies specific for endothelial cells and renal transplant failure

1998 • 74 citations

A thirty percent chronic decline in inverse serum creatinine is an excellent predictor of late renal allograft failure

2002 • 73 citations

Diagnostic criteria for chronic rejection/accelerated graft atherosclerosis in heart and kidney transplants: joint proposal from the Fourth Alexis Carrel Conference on Chronic Rejection and Accelerated Arteriosclerosis in Transplanted Organs.

1993 • 73 citations

Long-term anti-proteinuric effect of Losartan in renal transplant recipients treated for hypertension

2000 • 70 citations

HLA‐specific alloantibodies and renal graft outcome

2001 • 70 citations

Transplant capillaropathy and transplant glomerulopathy: ultrastructural markers of chronic renal allograft rejection

2003 • 70 citations

PROTEINURIA IN CYCLOSPORINE-TREATED RENAL TRANSPLANT RECIPIENTS

1990 • 68 citations

A multi-factor analysis of kidney graft outcomes at one and five years posttransplantation: 1996 UNOS Update.

1996 • 66 citations

IMPACT OF DONOR/RECIPIENT SIZE MATCHING ON OUTCOMES IN RENAL TRANSPLANTATION1

1996 • 66 citations

IMPACT OF THE BANFF ???97 CLASSIFICATION FOR HISTOLOGICAL DIAGNOSIS OF REJECTION ON CLINICAL OUTCOME AND RENAL FUNCTION PARAMETERS AFTER KIDNEY TRANSPLANTATION

2000 • 66 citations

Kidney Transplant Rejection

1987 • 65 citations

Focal segmental glomerulosclerosis in renal allografts with chronic nephropathy: Implications for graft survival

1999 • 65 citations

Oxidative modification of low-density lipoproteins and the outcome of renal allografts at 11/2 years

2001 • 63 citations

Coronary Artery Restenosis After Balloon Angioplasty in Humans Is Associated With Circumferential Coronary Constriction

1996 • 63 citations

COMPARISON OF MICROEMULSION AND CONVENTIONAL FORMULATIONS OF CYCLOSPORINE A IN PREVENTING ACUTE REJECTION IN DE NOVO KIDNEY TRANSPLANT PATIENTS1

1999 • 63 citations

The role of replicative senescence in chronic allograft nephropathy

2003 • 63 citations

Transplant glomerulopathy as a cause of late graft loss

2000 • 62 citations

THE ROLE OF THE ALLOGRAFT IN THE INDUCTION OF DONOR-SPECIFIC T CELL HYPORESPONSIVENESS

2001 • 61 citations

Development of cytotoxic antibodies following renal allograft transplantation is associated with reduced graft survival due to chronic vascular rejection

1994 • 59 citations

Ultrastructure of the glomerular basement membrane in long term renal allografts with transplant glomerular disease.

1974 • 59 citations

Persistent rejection of peritubular capillaries and tubules is associated with progressive interstitial fibrosis

2002 • 58 citations

Unique changes in interstitial extracellular matrix composition are associated with rejection and cyclosporine toxicity in human renal allograft biopsies

1999 • 57 citations

MATCHING FOR PRIVATE OR PUBLIC HLA EPITOPES REDUCES ACUTE REJECTION EPISODES AND IMPROVES TWO-YEAR RENAL ALLOGRAFT FUNCTION

1998 • 56 citations

THE INFLUENCE OF ACUTE REJECTION ON LONG-TERM RENAL ALLOGRAFT SURVIVAL: A COMPARISON OF LIVING AND CADAVERIC DONOR TRANSPLANTATION

2001 • 55 citations

Role of CD8+ lymphocytes in chronic rejection of transplanted hearts

2002 • 53 citations

Focal Segmental Glomerulosclerosis in Renal Transplants

1983 • 52 citations

Clinical significance of allograft glomerulopathy

1994 • 52 citations

A NEW ENZYME-LINKED IMMUNOSORBENT ASSAY TO MEASURE ANTI-ENDOTHELIAL ANTIBODIES AFTER CARDIAC TRANSPLANTATION DEMONSTRATES GREATER INHIBITION OF ANTIBODY FORMATION BY TACROLIMUS COMPARED WITH CYCLOSPORINE1

1998 • 50 citations

Sharing cross-reactive groups of MHC class I improves long-term graft survival

1999 • 49 citations

Hypertension is associated with hyperlipidemia, coronary heart disease and chronic graft failure in kidney transplant recipients.

1999 • 48 citations

Renal allograft survival following acute rejection correlates with blood pressure levels and histopathology

1999 • 48 citations

Chronic renal allograft rejection in the rat. Transplantation-induced antibodies against basement membrane antigens.

1994 • 47 citations

Acute rejection-associated tubular basement membrane defects and chronic allograft nephropathy

2000 • 47 citations

Prognosis After Primary Renal Transplant Failure And The Beneficial Effects of repeat Transplantation.

1999 • 46 citations

PERMANENT DETRIMENTAL EFFECT OF NONIMMUNOLOGICAL FACTORS ON LONG-TERM RENAL GRAFT SURVIVAL

2000 • 45 citations

Influence Of Hla Matching On Rejections And Short - And Long-Term Primary Cadaveric Allograft Survival

1993 • 44 citations

INDIRECT ALLORECOGNITION CAN PLAY AN IMPORTANT ROLE IN THE DEVELOPMENT OF TRANSPLANT ARTERIOSCLEROSIS1

2002 • 43 citations

DOES RENAL MASS EXERT AN INDEPENDENT EFFECT ON THE DETERMINANTS OF ANTIGEN-DEPENDENT INJURY?

2001 • 43 citations

MYOFIBROBLAST INVOLVEMENT IN CHRONIC TRANSPLANT REJECTION

1997 • 43 citations

PERITUBULAR CAPILLARY BASEMENT MEMBRANE REDUPLICATION IN ALLOGRAFTS AND NATIVE KIDNEY DISEASE

2001 • 43 citations

Completely reversed acute rejection is not a significant risk factor for the development of chronic rejection in renal allograft recipients

2000 • 42 citations

PREVALENCE OF DONOR-SPECIFIC ANTI-HLA ANTIBODIES DURING EPISODES OF RENAL ALLOGRAFT REJECTION1

2001 • 42 citations

Chronic rejection with or without transplant vasculopathy

2003 • 41 citations

CHRONIC RENAL ALLOGRAFT REJECTION

1998 • 41 citations

Kidney Transplant Rejection: Diagnosis and Treatment

1986 • 41 citations

Chronic allograft nephropathy—biopsy findings and outcome

2001 • 40 citations

Clinical predictors of chronic renal allograft rejection.

1995 • 40 citations

Glomerular hyperfiltration as a nonimmunologic mechanism of progression of chronic renal rejection.

1994 • 39 citations

INTERACTION OF MYCOPHENOLATE MOFETIL AND HLA MATCHING ON RENAL ALLOGRAFT SURVIVAL

2001 • 39 citations

Parameters associated with chronic renal transplant failure.

1997 • 39 citations

Completely reversed acute rejection is not a significant risk factor for the development of chronic rejection in renal allograft recipients

2000 • 39 citations

Antibodies against mesangial cells and their secretory products in chronic renal allograft rejection in the rat.

1998 • 38 citations

Immunohistological and ultrastructural differences between recurrent type I membranoproliferative glomerulonephritis and chronic transplant glomerulopathy

1998 • 37 citations

CD40 expression on graft infiltrates and parenchymal CD154 (CD40L) induction in human chronic renal allograft rejection

1999 • 37 citations

Renoprotective Effects of Losartan in Renal Transplant Recipients

2003 • 33 citations

Effect of early cyclosporine levels on kidney allograft rejection

1997 • 32 citations

Does antihypertensive therapy modify chronic allograft failure?

1995 • 32 citations

The effects of prolonged angiotensin-converting enzyme inhibition on excretory kidney function and proteinuria in renal allograft recipients with chronic progressive transplant failure

1996 • 31 citations

The HLA-matching effect in different cohorts of kidney transplant recipients.

2000 • 31 citations

New immunosuppressants and HLA matching

2001 • 30 citations

C4d deposition in the glomeruli and peritubular capillaries associated with transplant glomerulopathy

2003 • 23 citations

Role of antibodies in transplant-associated cardiac allograft vasculopathy

2000 • 21 citations

Antibodies directed against tubular basement membranes in human renal allograft recipients

1979 • 20 citations

The importance of humoral immune responses in chronic rejection

1998 • 20 citations

Antibodies to vascular endothelial cells in chronic rejection of renal allografts

2000 • 19 citations

Chronic cyclosporin nephropathy: long‐term effects of cyclosporin on renal allografts

2001 • 19 citations

Chronic Renal Transplant Rejection

1994 • 19 citations

Isolated iliac artery stenosis as a cause of kidney graft dysfunction post‐transplant

1998 • 18 citations

Conversion from cyclosporin (Neoral � ) to tacrolimus (Prograf � ) in renal allograft recipients with chronic graft nephropathy: results of an observational study

1999 • 18 citations

Mycophenolate mofetil decreases the risk for chronic renal allograft failure

2001 • 17 citations

The effects of prolonged angiotensin-converting enzyme inhibition on excretory kidney function and proteinuria in renal allograft recipients with chronic progressive transplant failure

1996 • 17 citations

Immune responsiveness and renal transplantation.

1996 • 14 citations

Increased expression of p21�(WAF1/CIP1) cyclin-dependent kinase (CDK) inhibitor gene in chronic allograft nephropathy correlates with the number of acute rejection episodes

2003 • 12 citations

Glomerular hypertension—an under‐appreciated aspect of chronic rejection

2001 • 12 citations

Post-transplant glomerular filtration rate as a marker for long-term outcome.

2000 • 11 citations

Risk factors of cyclosporine nephrotoxicity after conversion from Sandimmune to Neoral.

2001 • 10 citations

Fate of recurrent acute interstitial cellular rejection in an HLA identical kidney transplant recipient: impact of donor microchimerism.

1997 • 9 citations

Clinical importance of HLA-specific and non-HLA-specific antibodies in allogeneic kidney transplantation.

2000 • 9 citations

Increased expression of p21(WAF1/CIP1) CDKI gene in chronic allograft nephropathy correlating with the number of acute rejection episodes

2003 • 9 citations

Use of recombinase activation gene-2 deficient mice to ascertain the role of cellular and humoral immune responses in the development of chronic rejection

2002 • 8 citations

Acute renal allograft rejections, a role for statins?

2003 • 8 citations

Surrogate markers of chronic allograft nephropathy.

2000 • 6 citations

Significance of tubulitis in chronic allograft nephropathy: a clinicopathologic study

1997 • 4 citations

Pharmacotherapeutic Approach to Prevent or Treat Chronic Allograft Nephropathy

2002 • 3 citations

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