Chronic rejection in renal transplantation
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Abstract
References (206)
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Testing for Polyomavirus Type BK DNA in Plasma to Identify Renal-Allograft Recipients with Viral Nephropathy
2000 • 500 citations
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2001 • 470 citations
Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes
1998 • 466 citations
Beneficial effects of treatment of early subclinical rejection
1998 • 463 citations
Rethinking Chronic Allograft Nephropathy
1999 • 443 citations
Efficacy and safety of tacrolimus compared with ciclosporin microemulsion in renal transplantation: a randomised multicentre study
2002 • 440 citations
Capillary Deposition of Complement Split Product C4d in Renal Allografts is Associated with Basement Membrane Injury in Peritubular and Glomerular Capillaries
2002 • 425 citations
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2000 • 409 citations
MYCOPHENOLATE MOFETIL REDUCES LATE RENAL ALLOGRAFT LOSS INDEPENDENT OF ACUTE REJECTION
2000 • 409 citations
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1998 • 403 citations
ANTI-HLA ANTIBODIES AFTER SOLID ORGAN TRANSPLANTATION1
2000 • 384 citations
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1998 • 371 citations
Chronic allograft nephropathy: An update
1999 • 367 citations
CD4(+) T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver.
1997 • 365 citations
ACUTE HUMORAL REJECTION IN RENAL ALLOGRAFT RECIPIENTS: I. INCIDENCE, SEROLOGY AND CLINICAL CHARACTERISTICS1
2001 • 357 citations
Capillary C4d Deposition in Kidney Allografts
2002 • 342 citations
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1995 • 336 citations
Chronic renal allograft rejection: Immunologic and nonimmunologic risk factors
1996 • 325 citations
All chronic rejection failures of kidney transplants were preceded by the development of HLA antibodies
2002 • 319 citations
Delayed graft function influences renal function, but not survival
2000 • 299 citations
Posttransplantation production of donor HLA-specific antibodies as a predictor of renal transplant outcome1
2003 • 298 citations
Arterial Hypertension and Renal Allograft Survival
2000 • 294 citations
INDIRECT ALLORECOGNITION OF MAJOR HISTOCOMPATIBILITY COMPLEX ALLOPEPTIDES IN HUMAN RENAL TRANSPLANT RECIPIENTS WITH CHRONIC GRAFT DYSFUNCTION1
1997 • 290 citations
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1995 • 288 citations
SIROLIMUS REDUCES THE INCIDENCE OF ACUTE REJECTION EPISODES DESPITE LOWER CYCLOSPORINE DOSES IN CAUCASIAN RECIPIENTS OF MISMATCHED PRIMARY RENAL ALLOGRAFTS: A PHASE II TRIAL1
1999 • 279 citations
Neointimal and Tubulointerstitial Infiltration by Recipient Mesenchymal Cells in Chronic Renal-Allograft Rejection
2001 • 275 citations
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1994 • 270 citations
Renal Transplantation in Black Americans
2000 • 269 citations
THE IMPACT OF ACUTE REJECTION EPISODES ON LONG-TERM GRAFT FUNCTION AND OUTCOME IN 1347 PRIMARY RENAL TRANSPLANTS TREATED BY 3 CYCLOSPORINE REGIMENS
1993 • 268 citations
EFFECT OF HISTOLOGICAL DAMAGE ON LONG-TERM KIDNEY TRANSPLANT OUTCOME
2001 • 264 citations
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1994 • 259 citations
Chronic renal transplant loss
1995 • 254 citations
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1996 • 252 citations
Analysis of factors that affect outcome of primary cadaveric renal transplantation in the UK
1999 • 248 citations
Increased Immunogenicity and Cause of Graft Loss of Old Donor Kidneys
2001 • 247 citations
ANTIVIMENTIN ANTIBODIES ARE AN INDEPENDENT PREDICTOR OF TRANSPLANT-ASSOCIATED CORONARY ARTERY DISEASE AFTER CARDIAC TRANSPLANTATION1
2001 • 246 citations
Twelve Years' Experience with National Sharing of HLA-Matched Cadaveric Kidneys for Transplantation
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2002 • 245 citations
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1993 • 242 citations
A monoclonal antibody against GBM heparan sulfate induces an acute selective proteinuria in rats
1992 • 237 citations
Endothelial C4d deposition is associated with inferior kidney allograft outcome independently of cellular rejection
2001 • 234 citations
Delayed graft function of more than six days strongly decreases long-term survival of transplanted kidneys
1998 • 233 citations
The use of mycophenolate mofetil in transplant recipients
2000 • 233 citations
PROGNOSIS AFTER PRIMARY RENAL TRANSPLANT FAILURE AND THE BENEFICIAL EFFECTS OF REPEAT TRANSPLANTATION
1998 • 230 citations
C4d Deposition in Acute Rejection
2002 • 227 citations
The “injury response”: A concept linking nonspecific injury, acute rejection, and long-term transplant outcomes
1997 • 224 citations
Identification of the nonclassical HLA molecules, mica, as targets for humoral immunity associated with irreversible rejection of kidney allografts1
2002 • 205 citations
Chronic allograft nephropathy
2005 • 204 citations
THE RELATION BETWEEN ACUTE VASCULAR AND INTERSTITIAL RENAL ALLOGRAFT REJECTION AND SUBSEQUENT CHRONIC REJECTION
1995 • 204 citations
The renal risks of smoking
1997 • 201 citations
Humoral rejection in kidney transplantation: new concepts in diagnosis and treatment
2002 • 200 citations
Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shortening
2003 • 200 citations
Cadaver versus living donor kidneys: Impact of donor factors on antigen induction before transplantation
1999 • 182 citations
ASPIRIN, THROMBOSIS, AND THE FUTURE
1971 • 178 citations
Long-term impact of discontinued or reduced calcineurin inhibitor in patients with chronic allograft nephropathy
2001 • 177 citations
RISK FACTORS PREDICTING CHRONIC REJECTION OF RENAL ALLOGRAFTS
1994 • 175 citations
TRANSPLANT RENAL ARTERY STENOSIS IN 77 PATIENTS-DOES IT HAVE AN IMMUNOLOGICAL CAUSE?1
1996 • 161 citations
Morphological Spectrum of Polyoma Virus Disease in Renal Allografts: Diagnostic Accuracy of Urine Cytology
2001 • 158 citations
Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells
2003 • 157 citations
CONTROL OF ANTIDONOR ANTIBODY PRODUCTION WITH TACROLIMUS AND MYCOPHENOLATE MOFETIL IN RENAL ALLOGRAFT RECIPIENTS WITH CHRONIC REJECTION1
2001 • 156 citations
Kidney graft failure and presensitization against HLA Class I and Class II antigens1
2002 • 150 citations
EXCESS RISK OF RENAL ALLOGRAFT LOSS ASSOCIATED WITH CIGARETTE SMOKING
2001 • 148 citations
BIOPSY OF MARGINAL DONOR KIDNEYS: CORRELATION OF HISTOLOGIC FINDINGS WITH GRAFT DYSFUNCTION1
2000 • 148 citations
IMPACT OF ACUTE REJECTION AND EARLY ALLOGRAFT FUNCTION ON RENAL ALLOGRAFT SURVIVAL
1997 • 147 citations
Transplant glomerulopathy: Evolution of morphologically distinct changes
1985 • 146 citations
MEDICATION COMPLIANCE FOLLOWING RENAL TRANSPLANTATION
1999 • 145 citations
IMPACT OF DONOR-SPECIFIC ANTIBODIES ON CHRONIC REJECTION OCCURRENCE AND GRAFT LOSS IN RENAL TRANSPLANTATION: POSTTRANSPLANT ANALYSIS USING FLOW CYTOMETRIC TECHNIQUES1
2001 • 143 citations
Morphological Spectrum of Polyoma Virus Disease in Renal Allografts: Diagnostic Accuracy of Urine Cytology
2001 • 143 citations
Early versus late acute rejection episodes in renal transplantation
2003 • 140 citations
Enzyme-Linked Immunosorbent Spot Assay Analysis of Peripheral Blood Lymphocyte Reactivity to Donor HLA-DR Peptides
2002 • 137 citations
Detection of donor-specific anti-HLA antibodies with flow cytometry in eluates and sera from renal transplant recipients with chronic allograft nephropathy1
2003 • 133 citations
Immunologic risk factors and glomerular C4d deposits in chronic transplant glomerulopathy
2004 • 132 citations
Long‐Term Use of Mycophenolate Mofetil is Associated With a Reduction in the Incidence and Risk of Late Rejection
2003 • 125 citations
HYPERCHOLESTEROLEMIA IS ASSOCIATED WITH INCREASED KIDNEY GRAFT LOSS CAUSED BY CHRONIC REJECTION IN MALE PATIENTS WITH PREVIOUS ACUTE REJECTION
2000 • 121 citations
Association between specific HLA combinations and probability of kidney allograft loss: the taboo concept
1996 • 121 citations
Evolution of the Enzyme-Linked Immunosorbent Spot Assay for Post-Transplant Alloreactivity as a Potentially Useful Immune Monitoring Tool
2002 • 121 citations
DETERMINANTS OF CHRONIC RENAL ALLOGRAFT REJECTION IN CYCLOSPORINE-TREATED RECIPIENTS
1996 • 115 citations
Causes of late renal allograft loss: chronic allograft dysfunction, death, and other factors.
2001 • 111 citations
Increased expression of p16(INK4a) and p27(Kip1) cyclin-dependent kinase inhibitor genes in aging human kidney and chronic allograft nephropathy
2003 • 107 citations
THE VANISHING IMPORTANCE OF AGE IN RENAL TRANSPLANTATION
1999 • 107 citations
The Stability of the Glomerular Filtration Rate after Renal Transplantation Is Improving
2003 • 105 citations
Call for Revolution: A New Approach to Describing Allograft Deterioration
2002 • 105 citations
Impact of delayed graft function and acute rejection on graft survival
2002 • 102 citations
Why do we reject a graft? Role of indirect allorecognition in graft rejection
1999 • 100 citations
IS CHRONIC RENAL TRANSPLANT REJECTION A NON-IMMUNOLOGICAL PHENOMENON?
1986 • 100 citations
Replicative Senescence of Biliary Epithelial Cells Precedes Bile Duct Loss in Chronic Liver Allograft Rejection
2001 • 100 citations
Telomere Shortening and Cellular Senescence in a Model of Chronic Renal Allograft Rejection
2003 • 100 citations
Cell Senescence and Its Implications for Nephrology
2001 • 99 citations
Antibodies to basement membrane heparan sulfate proteoglycans bind to the laminae rarae of the glomerular basement membrane (GBM) and induce subepithelial GBM thickening.
1986 • 99 citations
DELAYED GRAFT FUNCTION DOES NOT REDUCE THE SURVIVAL OF RENAL TRANSPLANT ALLOGRAFTS
1998 • 98 citations
PROGRESSION OF KIDNEY DISEASE IN CHRONIC RENAL TRANSPLANT REJECTION
1991 • 98 citations
HLA MATCHMAKER: A MOLECULARLY BASED ALGORITHM FOR HISTOCOMPATIBILITY DETERMINATION
2003 • 97 citations
IMMUNOLOGIC FACTORS: THE MAJOR RISK FOR DECREASED LONG-TERM RENAL ALLOGRAFT SURVIVAL1,2
1999 • 96 citations
CHOLESTEROL AS AN INDEPENDENT PREDICTOR OF OUTCOME AFTER RENAL TRANSPLANTATION
2000 • 96 citations
Renal artery stenosis after kidney transplantation: Diagnostic and therapeutic approach
1998 • 93 citations
Peritubular Capillary Changes and C4d Deposits Are Associated with Transplant Glomerulopathy But Not IgA Nephropathy
2003 • 89 citations
Matching Older Kidneys with Older Patients Does Not Improve Allograft Survival
2002 • 89 citations
Glomerular Lesions in the Transplanted Kidney in Children
1987 • 88 citations
Delayed function reduces renal allograft survival independent of acute rejection
1996 • 86 citations
Peritubular capillaries in chronic renal allograft rejection: A quantitative ultrastructural study
2000 • 86 citations
Antibody Response Against Perlecan and Collagen Types IV and VI in Chronic Renal Allograft Rejection in the Rat
2002 • 84 citations
The nephrotoxicity of immunosuppressive drugs
1996 • 83 citations
OBSERVATIONS IN PATIENTS WITH A WELL‐TOLERATED HOMOTRANSPLANTED KIDNEY: POSSIBILITY OF A NEW SECONDARY DISEASE
1964 • 83 citations
VASCULAR ENDOTHELIAL GROWTH FACTOR EXPRESSION IN HUMAN CHRONIC RENAL ALLOGRAFT REJECTION1
1999 • 81 citations
Clinical correlation between renal allograft failure and hyperlipidemia.
1995 • 80 citations
The impact of late acute rejection after cadaveric kidney transplantation
2001 • 79 citations
HIGH INCIDENCE OF ANTITISSUE ANTIBODIES IN PATIENTS EXPERIENCING CHRONIC LIVER ALLOGRAFT REJECTION1
1998 • 78 citations
CLINICAL DETERMINANTS OF MULTIPLE ACUTE REJECTION EPISODES IN KIDNEY TRANSPLANT RECIPIENTS1
2000 • 77 citations
THE VARIABLE NATURE OF CHRONIC DECLINES IN RENAL ALLOGRAFT FUNCTION
1991 • 75 citations
An association between antibodies specific for endothelial cells and renal transplant failure
1998 • 74 citations
A thirty percent chronic decline in inverse serum creatinine is an excellent predictor of late renal allograft failure
2002 • 73 citations
Diagnostic criteria for chronic rejection/accelerated graft atherosclerosis in heart and kidney transplants: joint proposal from the Fourth Alexis Carrel Conference on Chronic Rejection and Accelerated Arteriosclerosis in Transplanted Organs.
1993 • 73 citations
Long-term anti-proteinuric effect of Losartan in renal transplant recipients treated for hypertension
2000 • 70 citations
HLA‐specific alloantibodies and renal graft outcome
2001 • 70 citations
Transplant capillaropathy and transplant glomerulopathy: ultrastructural markers of chronic renal allograft rejection
2003 • 70 citations
PROTEINURIA IN CYCLOSPORINE-TREATED RENAL TRANSPLANT RECIPIENTS
1990 • 68 citations
A multi-factor analysis of kidney graft outcomes at one and five years posttransplantation: 1996 UNOS Update.
1996 • 66 citations
IMPACT OF DONOR/RECIPIENT SIZE MATCHING ON OUTCOMES IN RENAL TRANSPLANTATION1
1996 • 66 citations
IMPACT OF THE BANFF ???97 CLASSIFICATION FOR HISTOLOGICAL DIAGNOSIS OF REJECTION ON CLINICAL OUTCOME AND RENAL FUNCTION PARAMETERS AFTER KIDNEY TRANSPLANTATION
2000 • 66 citations
Kidney Transplant Rejection
1987 • 65 citations
Focal segmental glomerulosclerosis in renal allografts with chronic nephropathy: Implications for graft survival
1999 • 65 citations
Oxidative modification of low-density lipoproteins and the outcome of renal allografts at 11/2 years
2001 • 63 citations
Coronary Artery Restenosis After Balloon Angioplasty in Humans Is Associated With Circumferential Coronary Constriction
1996 • 63 citations
COMPARISON OF MICROEMULSION AND CONVENTIONAL FORMULATIONS OF CYCLOSPORINE A IN PREVENTING ACUTE REJECTION IN DE NOVO KIDNEY TRANSPLANT PATIENTS1
1999 • 63 citations
The role of replicative senescence in chronic allograft nephropathy
2003 • 63 citations
Transplant glomerulopathy as a cause of late graft loss
2000 • 62 citations
THE ROLE OF THE ALLOGRAFT IN THE INDUCTION OF DONOR-SPECIFIC T CELL HYPORESPONSIVENESS
2001 • 61 citations
Development of cytotoxic antibodies following renal allograft transplantation is associated with reduced graft survival due to chronic vascular rejection
1994 • 59 citations
Ultrastructure of the glomerular basement membrane in long term renal allografts with transplant glomerular disease.
1974 • 59 citations
Persistent rejection of peritubular capillaries and tubules is associated with progressive interstitial fibrosis
2002 • 58 citations
Unique changes in interstitial extracellular matrix composition are associated with rejection and cyclosporine toxicity in human renal allograft biopsies
1999 • 57 citations
MATCHING FOR PRIVATE OR PUBLIC HLA EPITOPES REDUCES ACUTE REJECTION EPISODES AND IMPROVES TWO-YEAR RENAL ALLOGRAFT FUNCTION
1998 • 56 citations
THE INFLUENCE OF ACUTE REJECTION ON LONG-TERM RENAL ALLOGRAFT SURVIVAL: A COMPARISON OF LIVING AND CADAVERIC DONOR TRANSPLANTATION
2001 • 55 citations
Role of CD8+ lymphocytes in chronic rejection of transplanted hearts
2002 • 53 citations
Focal Segmental Glomerulosclerosis in Renal Transplants
1983 • 52 citations
Clinical significance of allograft glomerulopathy
1994 • 52 citations
A NEW ENZYME-LINKED IMMUNOSORBENT ASSAY TO MEASURE ANTI-ENDOTHELIAL ANTIBODIES AFTER CARDIAC TRANSPLANTATION DEMONSTRATES GREATER INHIBITION OF ANTIBODY FORMATION BY TACROLIMUS COMPARED WITH CYCLOSPORINE1
1998 • 50 citations
Sharing cross-reactive groups of MHC class I improves long-term graft survival
1999 • 49 citations
Hypertension is associated with hyperlipidemia, coronary heart disease and chronic graft failure in kidney transplant recipients.
1999 • 48 citations
Renal allograft survival following acute rejection correlates with blood pressure levels and histopathology
1999 • 48 citations
Chronic renal allograft rejection in the rat. Transplantation-induced antibodies against basement membrane antigens.
1994 • 47 citations
Acute rejection-associated tubular basement membrane defects and chronic allograft nephropathy
2000 • 47 citations
Prognosis After Primary Renal Transplant Failure And The Beneficial Effects of repeat Transplantation.
1999 • 46 citations
PERMANENT DETRIMENTAL EFFECT OF NONIMMUNOLOGICAL FACTORS ON LONG-TERM RENAL GRAFT SURVIVAL
2000 • 45 citations
Influence Of Hla Matching On Rejections And Short - And Long-Term Primary Cadaveric Allograft Survival
1993 • 44 citations
INDIRECT ALLORECOGNITION CAN PLAY AN IMPORTANT ROLE IN THE DEVELOPMENT OF TRANSPLANT ARTERIOSCLEROSIS1
2002 • 43 citations
DOES RENAL MASS EXERT AN INDEPENDENT EFFECT ON THE DETERMINANTS OF ANTIGEN-DEPENDENT INJURY?
2001 • 43 citations
MYOFIBROBLAST INVOLVEMENT IN CHRONIC TRANSPLANT REJECTION
1997 • 43 citations
PERITUBULAR CAPILLARY BASEMENT MEMBRANE REDUPLICATION IN ALLOGRAFTS AND NATIVE KIDNEY DISEASE
2001 • 43 citations
Completely reversed acute rejection is not a significant risk factor for the development of chronic rejection in renal allograft recipients
2000 • 42 citations
PREVALENCE OF DONOR-SPECIFIC ANTI-HLA ANTIBODIES DURING EPISODES OF RENAL ALLOGRAFT REJECTION1
2001 • 42 citations
Chronic rejection with or without transplant vasculopathy
2003 • 41 citations
CHRONIC RENAL ALLOGRAFT REJECTION
1998 • 41 citations
Kidney Transplant Rejection: Diagnosis and Treatment
1986 • 41 citations
Chronic allograft nephropathy—biopsy findings and outcome
2001 • 40 citations
Clinical predictors of chronic renal allograft rejection.
1995 • 40 citations
Glomerular hyperfiltration as a nonimmunologic mechanism of progression of chronic renal rejection.
1994 • 39 citations
INTERACTION OF MYCOPHENOLATE MOFETIL AND HLA MATCHING ON RENAL ALLOGRAFT SURVIVAL
2001 • 39 citations
Parameters associated with chronic renal transplant failure.
1997 • 39 citations
Completely reversed acute rejection is not a significant risk factor for the development of chronic rejection in renal allograft recipients
2000 • 39 citations
Antibodies against mesangial cells and their secretory products in chronic renal allograft rejection in the rat.
1998 • 38 citations
Immunohistological and ultrastructural differences between recurrent type I membranoproliferative glomerulonephritis and chronic transplant glomerulopathy
1998 • 37 citations
CD40 expression on graft infiltrates and parenchymal CD154 (CD40L) induction in human chronic renal allograft rejection
1999 • 37 citations
Renoprotective Effects of Losartan in Renal Transplant Recipients
2003 • 33 citations
Effect of early cyclosporine levels on kidney allograft rejection
1997 • 32 citations
Does antihypertensive therapy modify chronic allograft failure?
1995 • 32 citations
The effects of prolonged angiotensin-converting enzyme inhibition on excretory kidney function and proteinuria in renal allograft recipients with chronic progressive transplant failure
1996 • 31 citations
The HLA-matching effect in different cohorts of kidney transplant recipients.
2000 • 31 citations
New immunosuppressants and HLA matching
2001 • 30 citations
C4d deposition in the glomeruli and peritubular capillaries associated with transplant glomerulopathy
2003 • 23 citations
Role of antibodies in transplant-associated cardiac allograft vasculopathy
2000 • 21 citations
Antibodies directed against tubular basement membranes in human renal allograft recipients
1979 • 20 citations
The importance of humoral immune responses in chronic rejection
1998 • 20 citations
Antibodies to vascular endothelial cells in chronic rejection of renal allografts
2000 • 19 citations
Chronic cyclosporin nephropathy: long‐term effects of cyclosporin on renal allografts
2001 • 19 citations
Chronic Renal Transplant Rejection
1994 • 19 citations
Isolated iliac artery stenosis as a cause of kidney graft dysfunction post‐transplant
1998 • 18 citations
Conversion from cyclosporin (Neoral � ) to tacrolimus (Prograf � ) in renal allograft recipients with chronic graft nephropathy: results of an observational study
1999 • 18 citations
Mycophenolate mofetil decreases the risk for chronic renal allograft failure
2001 • 17 citations
The effects of prolonged angiotensin-converting enzyme inhibition on excretory kidney function and proteinuria in renal allograft recipients with chronic progressive transplant failure
1996 • 17 citations
Immune responsiveness and renal transplantation.
1996 • 14 citations
Increased expression of p21�(WAF1/CIP1) cyclin-dependent kinase (CDK) inhibitor gene in chronic allograft nephropathy correlates with the number of acute rejection episodes
2003 • 12 citations
Glomerular hypertension—an under‐appreciated aspect of chronic rejection
2001 • 12 citations
Post-transplant glomerular filtration rate as a marker for long-term outcome.
2000 • 11 citations
Risk factors of cyclosporine nephrotoxicity after conversion from Sandimmune to Neoral.
2001 • 10 citations
Fate of recurrent acute interstitial cellular rejection in an HLA identical kidney transplant recipient: impact of donor microchimerism.
1997 • 9 citations
Clinical importance of HLA-specific and non-HLA-specific antibodies in allogeneic kidney transplantation.
2000 • 9 citations
Increased expression of p21(WAF1/CIP1) CDKI gene in chronic allograft nephropathy correlating with the number of acute rejection episodes
2003 • 9 citations
Use of recombinase activation gene-2 deficient mice to ascertain the role of cellular and humoral immune responses in the development of chronic rejection
2002 • 8 citations
Acute renal allograft rejections, a role for statins?
2003 • 8 citations
Surrogate markers of chronic allograft nephropathy.
2000 • 6 citations
Significance of tubulitis in chronic allograft nephropathy: a clinicopathologic study
1997 • 4 citations
Pharmacotherapeutic Approach to Prevent or Treat Chronic Allograft Nephropathy
2002 • 3 citations
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