CD40 expression on graft infiltrates and parenchymal CD154 (CD40L) induction in human chronic renal allograft rejection

International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology

1993 • 1,431 citations

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

1997 • 936 citations

Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for CD40–CD40 ligand signaling in atherosclerosis

1997 • 737 citations

IMMUNE REGULATION BY CD40 AND ITS LIGAND GP39

1996 • 653 citations

CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.

1993 • 593 citations

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

1995 • 532 citations

Apoptosis: Activate NF-κB or die?

1997 • 524 citations

CD40 ligand-transduced co-stimulation of T cells in the development of helper function

1995 • 425 citations

Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

1996 • 416 citations

BOTH ALLOANTIGEN-DEPENDENT AND -INDEPENDENT FACTORS INFLUENCE CHRONIC ALLOGRAFT REJECTION

1995 • 378 citations

Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes.

1995 • 368 citations

BOTH ALLOANTIGEN-DEPENDENT AND -INDEPENDENT FACTORS INFLUENCE CHRONIC ALLOGRAFT REJECTION

1995 • 340 citations

CD40-gp39 INTERACTIONS PLAY A CRITICAL ROLE DURING ALLOGRAFT REJECTION

1996 • 331 citations

Chronic Allograft Rejection

1993 • 304 citations

TRANSPLANTATION TOLERANCE INDUCED BY CTLA4-Ig1

1994 • 303 citations

TRANSPLANTATION TOLERANCE INDUCED BY CTLA4-Ig1

1994 • 294 citations

A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation

1995 • 252 citations

CD80, CD86 and CD40 Provide Accessory Signals in a Multiple‐Step T‐Cell Activation Model

1996 • 243 citations

CYTOKINES, ADHESION MOLECULES, AND THE PATHOGENESIS OF CHRONIC REJECTION OF RAT RENAL ALLOGRAFTS

1993 • 218 citations

Intragraft TGF-β1 mRNA: A correlate of interstitial fibrosis and chronic allograft nephropathy

1996 • 193 citations

The CD40 pathway in allograft rejection, acceptance, and tolerance

1997 • 180 citations

Causes of Renal Allograft Loss

1991 • 176 citations

Immunohistologic analysis of renal CD40 and CD40L expression in lupus nephritis and other glomerulonephritides

1997 • 154 citations

MOLECULAR EXECUTORS OF CELL DEATH-DIFFERENTIAL INTRARENAL EXPRESSION OF Fas LIGAND, Fas, GRANZYME B, AND PERFORIN DURING ACUTE AND/OR CHRONIC REJECTION OF HUMAN RENAL ALLOGRAFTS1,2

1996 • 152 citations

Cross-linking of the CD40 ligand on human CD4+ T lymphocytes generates a costimulatory signal that up-regulates IL-4 synthesis.

1996 • 144 citations

UPREGULATION OF CYTOKINES ASSOCIATED WITH MACROPHAGE ACTIVATION IN THE LEWIS-TO-F344 RAT TRANSPLANTATION MODEL OF CHRONIC CARDIAC REJECTION1,2

1995 • 141 citations

Functional CD40 ligand expressed by human blood dendritic cells is up-regulated by CD40 ligation.

1996 • 140 citations

REVERSIBILITY OF CHRONIC RENAL ALLOGRAFT REJECTION

1994 • 130 citations

CD40 ligand is a T cell growth factor

1993 • 123 citations

Possible role for CD40-CD40L in the regulation of interstitial infiltration in the kidney

1997 • 119 citations

CD40 AND CD40 LIGAND (CD154) ARE COEXPRESSED ON MICROVESSELS IN VIVO IN HUMAN CARDIAC ALLOGRAFT REJECTION1,2

1997 • 117 citations

Effects of RS61443 on functional and morphological changes in chronically rejecting rat kidney allografts.

1995 • 116 citations

Chronic Rejection in Experimental Cardiac Transplantation: Studies in the Lewis‐F344 Model

1993 • 102 citations

Maintenance of nuclear factor-kappa B/Rel and c-myc expression during CD40 ligand rescue of WEHI 231 early B cells from receptor-mediated apoptosis through modulation of I kappa B proteins.

1996 • 97 citations

Characterization of CD40 signaling determinants regulating nuclear factor-kappa B activation in B lymphocytes.

1997 • 97 citations

PREVENTION OF CHRONIC REJECTION IN MOUSE AORTIC ALLOGRAFTS BY COMBINED TREATMENT WITH CTLA4-Ig AND ANTI-CD40 LIGAND MONOCLONAL ANTIBODY1,2

1997 • 96 citations

EFFECTS OF RS61443 ON FUNCTIONAL AND MORPHOLOGICAL CHANGES IN CHRONICALLY REJECTING RAT KIDNEY ALLOGRAFTS1,2

1995 • 94 citations

Induction, regulation, and function of soluble TRAP (CD40 ligand) during interaction of primary CD4⁺ CD45RA⁺ T cells with dendritic cells

1996 • 87 citations

Recombinant CD40 ligand exerts potent biologic effects on T cells.

1994 • 77 citations

An improved method for the inhibition of endogenous peroxidase non-deleterious to lymphocyte surface markers. Application to immunoperoxidase studies on eosinophil-rich tissue preparations

1987 • 71 citations

The CD40 Ligand Directly Activates T-Lymphocytes via Tyrosine Phosphorylation Dependent PKC Activation

1997 • 54 citations

Central role for CD40/CD40 ligand (CD154) interactions in transplant rejection.

1998 • 46 citations

Causes of renal allograft loss

1991 • 45 citations

T cell rescue of monocytes from apoptosis: role of the CD40-CD40L interaction and requirement for CD40-mediated induction of protein tyrosine kinase activity

1996 • 39 citations

INCREASED CD40 LIGAND GENE EXPRESSION DURING HUMAN RENAL AND MURINE ISLET ALLOGRAFT REJECTION1

1998 • 38 citations

IMMUNOLOCALIZATION OF FGF-1 AND RECEPTORS IN GLOMERULAR LESIONS ASSOCIATED WITH CHRONIC HUMAN RENAL ALLOGRAFT REJECTION1

1996 • 30 citations

Cleavage of membrane‐bound CD40 ligand is not required for inducing B cell proliferation and differentiation

1996 • 17 citations

In situ expression of cell growth factors in human renal chronic graft rejection

1997 • 7 citations

Immunohistochemistry and molecular biology markers of renal transplant rejection: Diagnostic applications

1996 • 2 citations

Prevention of chronic rejection of renal allografts in rats using a synthetic inhibitor of macrophage effector activation.

1995 • 2 citations

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