Role of CD8+ lymphocytes in chronic rejection of transplanted hearts

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1996 • 1,457 citations

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

1999 • 1,418 citations

Effect of Pravastatin on Outcomes after Cardiac Transplantation

1995 • 1,302 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1999 • 824 citations

PRIMARILY VASCULARIZED ALLOGRAFTS OF HEARTS IN MICE

1973 • 801 citations

4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

1997 • 777 citations

Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

1996 • 416 citations

Interferon-γ elicits arteriosclerosis in the absence of leukocytes

2000 • 375 citations

Human coronary transplantation-associated arteriosclerosis. Evidence for a chronic immune reaction to activated graft endothelial cells.

1991 • 325 citations

CD28-independent, TRAF2-dependent Costimulation of Resting T Cells by 4-1BB Ligand

1998 • 321 citations

Interferon-gamma deficiency prevents coronary arteriosclerosis but not myocardial rejection in transplanted mouse hearts.

1997 • 272 citations

Immunologic basis of transplant-associated arteriosclerosis.

1996 • 214 citations

CD40-CD40 Ligand-Independent Activation of CD8+ T Cells Can Trigger Allograft Rejection

2000 • 153 citations

UPREGULATION OF CYTOKINES ASSOCIATED WITH MACROPHAGE ACTIVATION IN THE LEWIS-TO-F344 RAT TRANSPLANTATION MODEL OF CHRONIC CARDIAC REJECTION1,2

1995 • 141 citations

ICAM-1 and B7-1 provide similar but distinct costimulation for CD8+ T cells, while CD4+ T cells are poorly costimulated by ICAM-1

1999 • 120 citations

Cardiac Allograft Vasculopathy

1995 • 107 citations

Regulation of adhesion molecule expression by CD8 T cells in vivo. I. Differential regulation of gp90MEL-14 (LECAM-1), Pgp-1, LFA-1, and VLA-4 alpha during the differentiation of cytotoxic T lymphocytes induced by allografts.

1992 • 105 citations

Coronary arteriosclerosis after T-cell-mediated injury in transplanted mouse hearts: role of interferon-gamma.

1998 • 94 citations

Reduced transplant arteriosclerosis in murine cardiac allografts placed in interferon-gamma knockout recipients.

1998 • 92 citations

MORPHOMETRIC ANALYSIS OF NEOINTIMAL FORMATION IN MURINE CARDIAC ALLOGRAFTS1

1997 • 79 citations

CORONARY ATHEROSCLEROSIS IN TRANSPLANTED MOUSE HEARTS

1994 • 78 citations

CD8+ T CELLS CONTRIBUTE TO THE DEVELOPMENT OF TRANSPLANT ARTERIOSCLEROSIS DESPITE CD154 BLOCKADE1

2000 • 77 citations

Mobilization of T lymphocytes following cardiac transplantation. Evidence that CD4-positive cells are required for cytotoxic T lymphocyte activation, inflammatory endothelial development, graft infiltration, and acute allograft rejection.

1992 • 72 citations

Sustained Anti-CD4/CD8 Treatment Blocks Inflammatory Activation and Intimal Thickening in Mouse Heart Allografts

1997 • 66 citations

Heart transplants in interferon-gamma, interleukin 4, and interleukin 10 knockout mice. Recipient environment alters graft rejection.

1997 • 66 citations

MOBILIZATION OF T LYMPHOCYTES FOLLOWING CARDIAC TRANSPLANTATION

1992 • 62 citations

EARLY AND LATE CHEMOKINE PRODUCTION CORRELATES WITH CELLULAR RECRUITMENT IN CARDIAC ALLOGRAFT VASCULOPATHY

2000 • 61 citations

CD40 Signaling Replaces CD4+ Lymphocytes and Its Blocking Prevents Chronic Rejection of Heart Transplants

2000 • 52 citations

Cardiac Allograft Vasculopathy Is Abrogated by Anti-CD8 Monoclonal Antibody Therapy

1997 • 49 citations

PROLONGED MURINE CARDIAC ALLOGRAFT ACCEPTANCE

1997 • 48 citations

Accelerated graft coronary artery disease: diagnosis and prevention.

1992 • 46 citations

Cardiac allograft atherosclerosis in the rat. The effect of histocompatibility factors, cyclosporine, and an angiotensin-converting enzyme inhibitor.

1994 • 39 citations

EVIDENCE THAT RECIPIENT CD8+ T CELL DEPLETION DOES NOT ALTER DEVELOPMENT OF CHRONIC VASCULAR REJECTION IN A RAT HEART ALLOGRAFT MODEL

1994 • 38 citations

CARDIAC ALLOGRAFT ATHEROSCLEROSIS IN THE RAT

1994 • 34 citations

Heart transplantation in patients with previous cardiac operations:

1994 • 27 citations

Experimental cardiac allograft vasculopathy in mice.

1993 • 17 citations

Contributions of cellular and humoral immunity to arteriopathic lesions in transplanted mouse hearts

1997 • 9 citations