Chronic allograft nephropathy: An update

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

Disruption of epithelial cell-matrix interactions induces apoptosis

1994 • 3,167 citations

The Banff 97 working classification of renal allograft pathology

1999 • 3,028 citations

Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation

1981 • 1,664 citations

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1996 • 1,457 citations

International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology

1993 • 1,431 citations

MYCOPHENOLATE MOFETIL FOR THE PREVENTION OF ACUTE REJECTION IN PRIMARY CADAVERIC RENAL ALLOGRAFT RECIPIENTS

1995 • 1,380 citations

Cyclosporine-Associated Chronic Nephropathy

1984 • 1,174 citations

A COMPARISON OF TACROLIMUS (FK506) AND CYCLOSPORINE FOR IMMUNOSUPPRESSION AFTER CADAVERIC RENAL TRANSPLANTATION1

1997 • 1,128 citations

Identification and characterization of a fibroblast marker: FSP1.

1995 • 1,050 citations

A BLINDED, RANDOMIZED CLINICAL TRIAL OF MYCOPHENOLATE MOFETIL FOR THE PREVENTION OF ACUTE REJECTION IN CADAVERIC RENAL TRANSPLANTATION1

1996 • 1,019 citations

PLACEBO-CONTROLLED STUDY OF MYCOPHENOLATE MOFETIL COMBINED WITH CYCLOSPORINE AND CORTICOSTEROIDS FOR PREVENTION OF ACUTE REJECTION

1995 • 985 citations

Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

1992 • 984 citations

Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection

1995 • 910 citations

Single base polymorphism in the human Tumour Necrosis Factor alpha (TNFα) gene detectable by Ncol restriction of PCR product

1992 • 903 citations

LRISK FACTORS FOR CHRONIC REJECTION IN RENAL ALLOGRAFT RECIPIENTS

1993 • 684 citations

Cardiovascular disease after renal transplantation.

1996 • 680 citations

Understanding the nature of renal disease progression

1997 • 655 citations

GENOTYPIC VARIATION IN THE TRANSFORMING GROWTH FACTOR-??1 GENE

1998 • 642 citations

Molecular insights into renal interstitial fibrosis.

1996 • 636 citations

Association of chronic kidney graft failure with recipient blood pressure

1998 • 596 citations

MYCOPHENOLATE MOFETIL IN RENAL ALLOGRAFT RECIPIENTS

1997 • 584 citations

Pathophysiology of chronic tubulo-interstitial disease in rats. Interactions of dietary acid load, ammonia, and complement component C3.

1985 • 482 citations

Interleukin 10 secretion in relation to human IL-10 locus haplotypes

1998 • 478 citations

THE IMPACT OF AN ACUTE REJECTION EPISODE ON LONG-TERM RENAL ALLOGRAFT SURVIVAL (t1/2)1,2

1994 • 444 citations

Rethinking Chronic Allograft Nephropathy

1999 • 443 citations

A BLINDED, LONG-TERM, RANDOMIZED MULTICENTER STUDY OF MYCOPHENOLATE MOFETIL IN CADAVERIC RENAL TRANSPLANTATION

1998 • 403 citations

DELETERIOUS EFFECTS OF DELAYED GRAFT FUNCTION IN CADAVERIC RENAL TRANSPLANT RECIPIENTS INDEPENDENT OF ACUTE REJECTION1,2,3

1998 • 381 citations

Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis

1989 • 354 citations

Chronic renal allograft rejection: Immunologic and nonimmunologic risk factors

1996 • 325 citations

In renal transplantation, one size may not fit all.

1992 • 323 citations

HYPERLIPIDEMIA IN SOLID ORGAN TRANSPLANTATION

1997 • 317 citations

Chronic Allograft Rejection

1993 • 304 citations

Long-Term Efficacy and Safety of Cyclosporine in Renal-Transplant Recipients

1994 • 273 citations

THE HYPERFILTRATION HYPOTHESIS IN HUMAN RENAL TRANSPLANTATION

1994 • 270 citations

Chronic renal transplant loss

1995 • 254 citations

Protein kinase C and protein tyrosine kinase activity contribute to mitogenic signaling by endothelin-1. Cross-talk between G protein-coupled receptors and pp60c-src

1993 • 230 citations

Tenascin in normal, reactive, hyperplastic, and neoplastic tissues: Biologic and pathologic implications

1991 • 225 citations

Patient survival after renal transplantation; more than 25 years follow-up

1997 • 224 citations

Lipids and Progressive Glomerulosclerosis

1988 • 207 citations

THE RELATION BETWEEN ACUTE VASCULAR AND INTERSTITIAL RENAL ALLOGRAFT REJECTION AND SUBSEQUENT CHRONIC REJECTION

1995 • 204 citations

Low-dose steroid therapy in cyclosporine-treated renal transplant recipients with well-functioning grafts. The Canadian Multicentre Transplant Study Group.

1992 • 202 citations

Significance of the donor age effect on kidney transplants

1997 • 186 citations

Causes of Renal Allograft Loss

1991 • 176 citations

Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection.

1996 • 170 citations

Beneficial effects of conversion from cyclosporin to azathioprine after kidney transplantation

1995 • 169 citations

THE RELATIVE EFFECTS OF FK506 AND CYCLOSPORINE ON SHORT- AND LONG-TERM KIDNEY GRAFT SURVIVAL1,2,3

1995 • 160 citations

Transforming growth factor-beta and matrix protein expression in acute and chronic rejection of human renal allografts.

1995 • 148 citations

Effect of anti-lymphocyte induction therapy on renal allograft survival

1997 • 142 citations

EFFECT OF THE MAINTENANCE IMMUNOSUPPRESSIVE DRUG REGIMEN ON KIDNEY TRANSPLANT OUTCOME

1994 • 136 citations

OBESITY AS A RISK FACTOR FOLLOWING RENAL TRANSPLANTATION1

1995 • 135 citations

Nephron supply is a major determinant of long-term renal allograft outcome in rats.

1994 • 134 citations

The Effect of Antilymphocyte Induction Therapy on Renal Allograft Survival

1998 • 128 citations

Late prednisone withdrawal in cyclosporine-treated kidney transplant patients

1997 • 123 citations

Chronic allograft nephropathy in the rat is improved by angiotensin II receptor blockade but not by calcium channel antagonism.

1998 • 120 citations

The prognostic significance of specific arterial lesions in acute renal allograft rejection.

1998 • 118 citations

Efficacy of rejection prophylaxis with OKT3 in renal transplantation. Collaborative Transplant Study.

1995 • 112 citations

Stabile D‐peptide analog of insulin‐like growth factor‐l inhibits smooth muscle cell proliferation after carotid ballooning injury in the rat

1995 • 103 citations

Analysis of chronic rejection and obliterative arteriopathy. Possible contributions of donor antigen-presenting cells and lymphatic disruption.

1997 • 98 citations

Fas-dependent fratricidal apoptosis is a mechanism of tubular epithelial cell deletion in chronic renal failure.

1998 • 94 citations

Elective cyclosporine withdrawal after renal transplantation. A meta-analysis.

1993 • 94 citations

EFFICACY OF REJECTION PROPHYLAXIS WITH OKT3 IN RENAL TRANSPLANTATION

1995 • 93 citations

ANTIHYPERTENSIVE DRUG TREATMENT IN CHRONIC RENAL ALLOGRAFT REJECTION IN THE RAT

1996 • 89 citations

Glomerular Lesions in the Transplanted Kidney in Children

1987 • 88 citations

Critical evaluation of the association of acute with chronic graft rejection in kidney and heart transplant recipients

1997 • 87 citations

Hyperlipidaemia in renal transplantation—risk factor for long‐term graft outcome

1995 • 86 citations

Progression of chronic renal disease in humans is associated with the deposition of basement membrane components and decorin in the interstitial extracellular matrix.

1995 • 83 citations

OBSERVATIONS IN PATIENTS WITH A WELL‐TOLERATED HOMOTRANSPLANTED KIDNEY: POSSIBILITY OF A NEW SECONDARY DISEASE

1964 • 83 citations

STEROID WITHDRAWAL IN MYCOPHENOLATE MOFETIL-TREATED RENAL ALLOGRAFT RECIPIENTS

1997 • 80 citations

Chronic glucocorticoid therapy amplifies glomerular injury in rats with renal ablation.

1987 • 78 citations

THE VARIABLE NATURE OF CHRONIC DECLINES IN RENAL ALLOGRAFT FUNCTION

1991 • 75 citations

Elective Cyclosporine Withdrawal After Renal Transplantation

1993 • 75 citations

Angiotensin II Receptor Antagonist TCV-116 Reduces Graft Coronary Artery Disease and Preserves Graft Status in a Murine Model

1996 • 74 citations

Diagnostic criteria for chronic rejection/accelerated graft atherosclerosis in heart and kidney transplants: joint proposal from the Fourth Alexis Carrel Conference on Chronic Rejection and Accelerated Arteriosclerosis in Transplanted Organs.

1993 • 73 citations

Influence of Cytokine Genotypes on Allograft Rejection

1998 • 72 citations

Differential distribution of tenascin and cellular fibronectins in acute and chronic renal allograft rejection.

1992 • 71 citations

Somatostatin analog Lanreotide inhibits myocyte replication and several growth factors in allograft arteriosclerosis

1993 • 69 citations

RAPAMYCIN INHIBITS TRANSPLANT VASCULOPATHY IN LONG-SURVIVING RAT HEART ALLOGRAFTS

1995 • 68 citations

A multi-factor analysis of kidney graft outcomes at one and five years posttransplantation: 1996 UNOS Update.

1996 • 66 citations

Effects of dietary protein in patients with chronic renal transplant rejection

1992 • 65 citations

Intertubular capillary changes in kidney allografts: a morphologic investigation on 61 renal specimens.

1992 • 64 citations

Coronary Artery Restenosis After Balloon Angioplasty in Humans Is Associated With Circumferential Coronary Constriction

1996 • 63 citations

Recipient body size and cadaveric renal allograft survival.

1996 • 62 citations

Inhibition of Transplant Coronary Arteriosclerosis in Rabbits by Chronic Estradiol Treatment Is Associated With Abolition of MHC Class II Antigen Expression

1996 • 62 citations

Microvascular Changes in Renal Allografts Associated with FK506 (Tacrolimus) Therapy

1996 • 61 citations

Renal mass as a determinant of late allograft outcome: insights from experimental studies in rats.

1995 • 60 citations

Factors Affecting Renal Allograft Function in Long-Term Recipients

1992 • 59 citations

Survival trends in long-term first cadaver-donor kidney transplants.

1991 • 57 citations

Unique changes in interstitial extracellular matrix composition are associated with rejection and cyclosporine toxicity in human renal allograft biopsies

1999 • 57 citations

Role of Iron and Oxygen Radicals in the Progression of Chronic Renal Failure

1994 • 57 citations

A specific glomerular lesion of the graft: allograft glomerulopathy.

1993 • 56 citations

TREATMENT OF HYPERLIPIDEMIA IN RENAL TRANSPLANT RECIPIENTS1

1997 • 53 citations

Growth factor transcripts in rat renal transplants

1996 • 52 citations

Focal Segmental Glomerulosclerosis in Renal Transplants

1983 • 52 citations

Decorin regulates collagenase gene expression in fibroblasts adhering to vitronectin

1996 • 50 citations

Chronic renal allograft rejection in the rat. Transplantation-induced antibodies against basement membrane antigens.

1994 • 47 citations

MECHANISMS OF LYMPHOCYTE-MEDIATED CYTOTOXICITY IN ACUTE RENAL ALLOGRAFT REJECTION1

1998 • 46 citations

Protecting single-kidney allografts from long-term functional deterioration.

1998 • 45 citations

GLOMERULAR CAPILLARY PRESSURES IN LONG-SURVIVING RAT RENAL ALLOGRAFTS

1993 • 44 citations

Elevated neointimal endothelin-1 in transplantation-associated arteriosclerosis of renal allograft recipients

1998 • 43 citations

OBSERVATIONS IN PATIENTS WITH A WELL‐TOLERATED HOMOTRANSPLANTED KIDNEY:POSSIBILITY OF A NEW SECONDARY DISEASE

1965 • 43 citations

Endoglin, a transforming growth factor-beta-binding protein, is upregulated in chronic progressive renal disease.

1997 • 42 citations

Clinical predictors of chronic renal allograft rejection.

1995 • 40 citations

Glomerular hyperfiltration as a nonimmunologic mechanism of progression of chronic renal rejection.

1994 • 39 citations

Antibodies against mesangial cells and their secretory products in chronic renal allograft rejection in the rat.

1998 • 38 citations

GLOMERULAR HYPERFILTRATION AS A NONIMMUNOLOGIC MECHANISM OF PROGRESSION OF CHRONIC RENAL REJECTION

1994 • 36 citations

A ten-year prediction for kidney transplant survival.

1992 • 36 citations

The potential impact of the reperfusion injury on acute and chronic rejection events following organ transplantation.

1994 • 32 citations

Does antihypertensive therapy modify chronic allograft failure?

1995 • 32 citations

ACTIVATION OF THE SERINE PROTEINASE SYSTEM IN CHRONIC KIDNEY REJECTION1

1998 • 31 citations

The effects of prolonged angiotensin-converting enzyme inhibition on excretory kidney function and proteinuria in renal allograft recipients with chronic progressive transplant failure

1996 • 31 citations

L-arginine prevents heart transplant arteriosclerosis by modulating the vascular cell proliferative response to insulin-like growth factor-I and interleukin-6.

1996 • 31 citations

A reduction in accelerated graft coronary disease and an improvement in cardiac allograft survival using low molecular weight heparin in combination with cyclosporine.

1993 • 29 citations

Do prophylactic antilymphocyte globulins (ALG and OKT3) improve renal transplant survival in recipient and donor high-risk groups?

1993 • 28 citations

MAINTENANCE THERAPY WITH TRIPLE VERSUS DOUBLE IMMUNOSUPPRESSIVE REGIMEN IN RENAL TRANSPLANTATION

1997 • 25 citations

Chronic renal allograft rejection and clinical trial design.

1995 • 24 citations

Immunosuppressive regimens and their effects on renal allograft outcome.

1996 • 21 citations

The Transplanted Kidney

1985 • 21 citations

Antibodies directed against tubular basement membranes in human renal allograft recipients

1979 • 20 citations

Patient noncompliance as a cause of late kidney graft failure.

1992 • 18 citations

The effects of prolonged angiotensin-converting enzyme inhibition on excretory kidney function and proteinuria in renal allograft recipients with chronic progressive transplant failure

1996 • 17 citations

Dietary protein and the renin-angiotensin system in chronic renal allograft rejection.

1995 • 16 citations

Physiological and structural responses to chronic experimental renal allograft injury

1994 • 16 citations

Long-term results of cyclosporine monotherapy in kidney transplantation.

1991 • 14 citations

LACK OF EFFECT OF RECOMBINANT HUMAN SUPEROXIDE DISMUTASE ON COLD ISCHEMIA-INDUCED ARTERIOSCLEROSIS IN SYNGENEIC RAT AORTIC TRANSPLANTS1

1996 • 13 citations

Kidney Lymphatics: An Important Network in Transplantation

1974 • 13 citations

Separate risk factors for the development of transplant glomerulopathy vs chronic tubulointerstitial rejection

1997 • 12 citations

Renal transplant fibrosis: Histomorphometric assessment of early renal transplant biopsies for markers of chronic rejection

1997 • 12 citations

A RANDOMIZED TRIAL COMPARING CYCLOSPORINE AND STEROIDS WITH CYCLOSPORINE, AZATHIOPRINE, AND STEROIDS IN CADAVERIC RENAL TRANSPLANTATION1

1998 • 12 citations

Lymph Vessels of the Transplanted Kidney

1986 • 11 citations

Lymphatic arteriopathy: damage to the wall of the canine femoral artery after lymphatic blockade.

1991 • 8 citations

Renal arteriopathy associated with FK 506 therapy following liver transplantation

1994 • 8 citations

Effect of RS61443 on chronic rejection of rat kidney allografts.

1995 • 7 citations

Impact of cyclosporine on chronic rejection and graft vasculopathy.

1994 • 4 citations

Prophylactic antilymphocyte antibody therapy in kidney transplantation: Quo vadis?

1995 • 3 citations

Macrophages and HLA‐DR(+) cells in acutely rejecting kidney transplants, predict subsequent graft survival, even after reversal of the acute episode

1998 • 3 citations

Macrophages and HLA‐DR(+) cells in acutely rejecting kidney transplants, predict subsequent graft survival, even after reversal of the acute episode

1998 • 3 citations

MULTILAMELLATION OF THE PERITUBULAR CAPILLARY BASEMENT MEMBRANE IN CHRONIC RENAL ALLOGRAFT REJECTION

1998 • 3 citations

Surrogate end points in chronic kidney graft rejection studies

1999 • 3 citations

Deleted Work

1955 • 0 citations