Antioxidant and prooxidant activity of alpha-tocopherol in human plasma and low density lipoprotein.

Beyond Cholesterol

1989 • 6,533 citations

Direct transesterification of all classes of lipids in a one-step reaction.

1986 • 2,353 citations

The role of lipid peroxidation and antioxidants in oxidative modification of LDL

1992 • 2,335 citations

Ascorbate is an outstanding antioxidant in human blood plasma.

1989 • 1,876 citations

Continuous Monitoring ofin VztroOxidation of Human Low Density Lipoprotein

1989 • 1,824 citations

Antioxidant defenses and lipid peroxidation in human blood plasma.

1988 • 1,253 citations

Separation of plasma lipoproteins by density-gradient ultracentrifugation

1975 • 1,114 citations

Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol.

1991 • 786 citations

Autoxidation of human low density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes

1987 • 773 citations

Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein

1993 • 710 citations

Role of vitamin E in preventing the oxidation of low-density lipoprotein

1991 • 649 citations

Inhibition of oxidation of methyl linoleate in solution by vitamin E and vitamin C.

1984 • 580 citations

Ataxia with isolated vitamin E deficiency is caused by mutations in the α–tocopherol transfer protein

1995 • 561 citations

Determination of Cholesterol Oxidation Products in Human Plasma by Isotope Dilution-Mass Spectrometry

1995 • 547 citations

Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant

1992 • 513 citations

Free and albumin-bound bilirubin are efficient co-antioxidants for alpha-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation

1994 • 512 citations

Effect of oral supplementation with D-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation.

1991 • 477 citations

Effect of dietary antioxidant combinations in humans. Protection of LDL by vitamin E but not by beta-carotene.

1993 • 408 citations

Supplementation with vitamin E but not beta-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro. Effect of cigarette smoking.

1992 • 354 citations

Improved Measurement of Low-Density-Lipoprotein Susceptibility to Copper-Induced Oxidation: Application of a Short Procedure for Isolating Low-Density Lipoprotein

1992 • 352 citations

Effect of dietary supplementation with alpha-tocopherol on the oxidative modification of low density lipoprotein.

1992 • 299 citations

[46] Methods to determine oxidation of low-density lipoproteins

1994 • 283 citations

Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. Anti- rather than prooxidant activity of vitamin C in the presence of transition metal ions.

1993 • 278 citations

Role of oxidised low density lipoprotein in atherogenesis

1993 • 230 citations

Prevention of Tocopherol-mediated Peroxidation in Ubiquinol-10-free Human Low Density Lipoprotein

1995 • 215 citations

Therapeutic potential of vitamin E in the pathogenesis of spontaneous atherosclerosis

1991 • 164 citations

Oxidative susceptibility of low density lipoprotein subfractions is related to their ubiquinol-10 and alpha-tocopherol content.

1994 • 158 citations

Lipoprotein oxidation: mechanistic aspects, methodological approaches and clinical relevance.

1994 • 154 citations

Reduction of Copper, but Not Iron, by Human Low Density Lipoprotein (LDL)

1995 • 152 citations

Impaired discrimination between stereoisomers of alpha-tocopherol in patients with familial isolated vitamin E deficiency.

1993 • 139 citations

Vitamin E content and low density lipoprotein oxidizability induced by free radicals

1990 • 137 citations

A simple test for predisposition to LDL oxidation based on the fluorescence development during copper-catalyzed oxidative modification.

1991 • 135 citations

Reaction of Ascorbate with the α-Tocopheroxyl Radical in Micellar and Bilayer Membrane Systems

1995 • 127 citations

Lipoprotein oxidation

1994 • 122 citations

Plasma Copper and Antioxidant Status in Wilson's Disease

1995 • 118 citations

α-Tocopherol as a Reductant for Cu(II) in Human Lipoproteins

1996 • 117 citations

Oxidation of low-density lipoproteins: questions of initiation, propagation, and the effect of antioxidants

1995 • 113 citations

Monitoring of Ubiquinol-10, Ubiquinone-10, Carotenoids, and Tocopherols in Neonatal Plasma Microsamples Using High-Performance Liquid Chromatography with Coulometric Electrochemical Detection

1995 • 109 citations

Analysis of plasma cholesterol oxidation products using gas- and high-performance liquid chromatography/mass spectrometry

1994 • 108 citations

Oxidation resistance, oxidation rate, and extent of oxidation of human low-density lipoprotein depend on the ration of oleic acid content to linoleic acid content studies in vitamin E deficient subjects

1993 • 104 citations

Supplementation with Vitamin E but Not Beta-Carotene in Vivo Protects Low Density Lipoprotein from Lipid Peroxidation in Vitro

1992 • 99 citations

Oxidative damage and erythrocyte membrane transport abnormalities in thalassemias

1994 • 85 citations

Analysis of Lipoprotein Diene Formation in Human Serum Exposed to Copper

1993 • 84 citations

Copper-Induced Lipid Oxidation in Unfractionated Plasma: The Lag Preceding Oxidation as a Measure of Oxidation-Resistance

1995 • 71 citations

Low density lipoprotein oxidizability by copper correlates to its initial ubiquinol‐10 and polyunsaturated fatty acid content

1994 • 70 citations

Oxidation of low-density lipoproteins: effect of antioxidant content, fatty acid composition and intrinsic phospholipase activity on susceptibility to metal ion-induced oxidation

1995 • 55 citations

A treatable familial neuromyopathy with vitamin E deficiency, normal absorption, and evidence of increased consumption of vitamin E

1988 • 51 citations

How Different Constituents of Low Density Lipoprotein Determine its Oxidizability by Copper: A Correlational Approach

1996 • 49 citations

Predisposition to LDL oxidation during copper-catalyzed oxidative modification and its relation to α-tocopherol content in humans

1991 • 48 citations

The role of α-tocopherol as a peroxyl radical scavenger in human low density lipoprotein

1993 • 42 citations

Vitamin E: The Antioxidant Harvesting Center of Membranes and Lipoproteins

2023 • 5 citations