Prevention of Tocopherol-mediated Peroxidation in Ubiquinol-10-free Human Low Density Lipoprotein

Beyond Cholesterol

1989 • 6,533 citations

Bilirubin Is an Antioxidant of Possible Physiological Importance

1987 • 3,406 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

Vitamin E Consumption and the Risk of Coronary Heart Disease in Men

1993 • 2,363 citations

Vitamin E Consumption and the Risk of Coronary Disease in Women

1993 • 2,158 citations

Book ReviewAmbulatory Pediatric Care

1989 • 2,075 citations

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

1984 • 1,631 citations

Direct observation of a free radical interaction between vitamin E and vitamin C

1979 • 1,460 citations

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

1992 • 1,332 citations

Antioxidant defenses and lipid peroxidation in human blood plasma.

1988 • 1,253 citations

Vitamin E: application of the principles of physical organic chemistry to the exploration of its structure and function

1986 • 1,103 citations

Autoxidation of biological molecules. 1. Antioxidant activity of vitamin E and related chain-breaking phenolic antioxidants in vitro

1981 • 1,071 citations

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1987 • 1,051 citations

The relative contributions of vitamin E, urate, ascorbate and proteins to the total peroxyl radical-trapping antioxidant activity of human blood plasma

1987 • 889 citations

Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol.

1991 • 786 citations

Autoxidation of human low density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes

1987 • 773 citations

Malondialdehyde-Altered Protein Occurs in Atheroma of Watanabe Heritable Hyperlipidemic Rabbits

1988 • 757 citations

Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein

1993 • 710 citations

Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant

1992 • 513 citations

Free and albumin-bound bilirubin are efficient co-antioxidants for alpha-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation

1994 • 512 citations

A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein

1989 • 480 citations

High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors.

1992 • 471 citations

Association of low serum concentration of bilirubin with increased risk of coronary artery disease

1994 • 466 citations

Antioxidant and co-antioxidant activity of vitamin C. The effect of vitamin C, either alone or in the presence of vitamin E or a water-soluble vitamin E analogue, upon the peroxidation of aqueous multilamellar phospholipid liposomes

1985 • 428 citations

Autoxidation of lipids and antioxidation by alpha-tocopherol and ubiquinol in homogeneous solution and in aqueous dispersions of lipids: unrecognized consequences of lipid particle size as exemplified by oxidation of human low density lipoprotein.

1993 • 342 citations

Induction of Haem Oxygenase as a Defence Against Oxidative Stress

1990 • 322 citations

Antioxidant activities of some tryptophan metabolites: possible implication for inflammatory diseases.

1990 • 320 citations

Ascorbic acid protects lipids in human plasma and low-density lipoprotein against oxidative damage

1991 • 317 citations

[50] Rapid isolation of lipoproteins and assessment of their peroxidation by high-performance liquid chromatography postcolumn chemiluminescence

1994 • 313 citations

Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation

1992 • 309 citations

Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation

1989 • 294 citations

SOME PROPERTIES OF THE ASCORBATE FREE RADICAL^*

1975 • 262 citations

Effect of phytyl side chain of vitamin E on its antioxidant activity.

1985 • 218 citations

Low density lipoprotein is protected from oxidation and the progression of atherosclerosis is slowed in cholesterol-fed rabbits by the antioxidant N,N'-diphenyl-phenylenediamine.

1992 • 207 citations

The Surprisingly High Reactivity of Phenoxyl Radicals

1994 • 161 citations

Lesion-derived low density lipoprotein and oxidized low density lipoprotein share a lability for aggregation, leading to enhanced macrophage degradation.

1991 • 158 citations

1992 Syntex Award Lecture Model biomembranes: quantitative studies of peroxidation, antioxidant action, partitioning, and oxidative stress

1993 • 157 citations

Free radical modification of low-density lipoprotein: Mechanisms and biological consequences

1987 • 150 citations

The effect of α-tocopherol as an antioxidant on the oxidation of membrane protein thiols induced by free radicals generated in different sites

1991 • 130 citations

Dynamics of the oxidation of low density lipoprotein induced by free radicals

1993 • 123 citations

Antioxidant activity of probucol and its analogs in hypercholesterolemic Watanabe rabbits

1991 • 116 citations

Structure-activity relationship in the quenching reaction of singlet oxygen by tocopherol (vitamin E) derivatives and related phenols. Finding of linear correlation between the rates of quenching of singlet oxygen and scavenging of peroxyl and phenoxyl radicals in solution

1991 • 109 citations

Concentration-dependent antioxidant activity of probucol in low density lipoproteins in vitro: probucol degradation precedes lipoprotein oxidation.

1989 • 107 citations

Inhibition by interferon-gamma of human mononuclear cell-mediated low density lipoprotein oxidation. Participation of tryptophan metabolism along the kynurenine pathway.

1994 • 96 citations

The cooperative antioxidant role of glutathione with a lipid-soluble and a water-soluble antioxidant during peroxidation of liposomes initiated in the aqueous phase and in the lipid phase.

1988 • 93 citations

Pro-oxidant effects of lipoxygenase-derived peroxides on the copper-initiated oxidation of low-density lipoprotein

1992 • 93 citations

The Oxidation Product from α-Tocopherol and Potassium Ferricyanide and Its Reaction with Ascorbic and Hydrochloric Acids

1962 • 92 citations

Antioxidant activities of probucol against lipid peroxidations

1992 • 81 citations

Antioxidant and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: Comparison of their mechanism of protection with that of desferrioxamine

1992 • 77 citations

Probucol treatment affects the cellular composition but not anti-oxidized low density lipoprotein immunoreactivity of plaques from Watanabe heritable hyperlipidemic rabbits.

1991 • 73 citations

[8] Use of ascorbate as test for catalytic metals in simple buffers

1990 • 66 citations

Reactions of the α‐tocopheroxyl radical in micellar solutions studied by nanosecond laser flash photolysis

1991 • 60 citations

Autoxidation of micelle-solubilized linoleic acid. Relative inhibitory efficiencies of ascorbate and ascorbyl palmitate

1985 • 50 citations

Oxidation of 3-hydroxyanthranilic acid to the phenoxazinone cinnabarinic acid by peroxyl radicals and by compound I of peroxidases or catalase

1992 • 42 citations

Antioxidant activity of oxidation products of α‐tocopherol and of its model compound 2,2,5,7,8‐pentamethyl‐6‐chromanol

1991 • 17 citations

Kinetics of the reaction between ascorbate and free radical from vitamin E as studied by ESR steady-state method

1993 • 14 citations