Supplementation with vitamin E but not beta-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro. Effect of cigarette smoking.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Beyond Cholesterol

1989 • 6,533 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

β-Carotene: an Unusual Type of Lipid Antioxidant

1984 • 2,147 citations

Continuous Monitoring ofin VztroOxidation of Human Low Density Lipoprotein

1989 • 1,824 citations

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

1984 • 1,631 citations

Free-radical chemistry of cigarette smoke and its toxicological implications.

1985 • 1,351 citations

Cholesterol in the Prediction of Atherosclerotic Disease

1979 • 1,333 citations

Norepinephrine and Epinephrine Release and Adrenergic Mediation of Smoking-Associated Hemodynamic and Metabolic Events

1976 • 1,114 citations

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1987 • 1,051 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia.

1987 • 885 citations

Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation.

1984 • 826 citations

Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene

1991 • 788 citations

Autoxidation of human low density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes

1987 • 773 citations

Antioxidants in relation to lipid peroxidation

1987 • 684 citations

Role of vitamin E in preventing the oxidation of low-density lipoprotein

1991 • 649 citations

Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid.

1983 • 623 citations

Role of oxidatively modified LDL in atherosclerosis

1990 • 614 citations

Biological actions of carotenoids ¹

1989 • 559 citations

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture.

1984 • 547 citations

Monocytes and Neutrophils Oxidize Low Density Lipoprotein Making It Cytotoxic

1985 • 536 citations

Biochemical structural and functional properties of oxidized low-density lipoprotein

1990 • 536 citations

THE RELATION OF DIET, CIGARETTE SMOKING, AND ALCOHOL CONSUMPTION TO PLASMA BETA-CAROTENE AND ALPHA-TOCOPHEROL LEVELS

1988 • 526 citations

Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Protective effects of ascorbic acid

1991 • 485 citations

Effect of oral supplementation with D-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation.

1991 • 477 citations

Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism.

1987 • 473 citations

Antioxidant Action of Carotenoids

1989 • 449 citations

Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor.

1986 • 417 citations

Improved techniques for the separation of serum lipoproteins by density gradient ultracentrifugation: Visualization by prestaining and rapid separation of serum lipoproteins from small volumes of serum

1981 • 378 citations

Presence of a modified low density lipoprotein in humans.

1988 • 373 citations

The antioxidant butylated hydroxytoluene protects against atherosclerosis.

1991 • 362 citations

α-tocopherol consumption during low-density-lipoprotein oxidation

1990 • 312 citations

Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cells

1991 • 275 citations

Superoxide initiates oxidation of low density lipoprotein by human monocytes.

1987 • 273 citations

Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma

1988 • 255 citations

Plasma Vitamins E and A Inversely Correlated to Mortality from Ischemic Heart Disease in Cross‐Cultural Epidemiology

1989 • 240 citations

Smoking-induced coronary vasoconstriction in patients with atherosclerotic coronary artery disease: evidence for adrenergically mediated alterations in coronary artery tone.

1986 • 237 citations

Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells.

1985 • 219 citations

Lower levels of vitamin C and carotenes in plasma of cigarette smokers.

1986 • 204 citations

Cigarette smoking renders LDL susceptible to peroxidative modification and enhanced metabolism by macrophages

1989 • 191 citations

Deficiency of vitamin E in the alveolar fluid of cigarette smokers. Influence on alveolar macrophage cytotoxicity.

1986 • 182 citations

Fluorometric determination of total vitamin C in whole blood by high-performance liquid chromatography with pre-column derivatization

1984 • 181 citations

On the Antioxidant Hypothesis with Regard to Arteriosclerosis1

1986 • 163 citations

Role of endothelial cells and their products in the modification of low-density lipoproteins

1986 • 159 citations

Cholesteryl ester accumulation in macrophages incubated with low density lipoprotein pretreated with cigarette smoke extract.

1988 • 147 citations

Plasma lipid and lipoprotein profiles of cigarette smokers from randomly selected families: Enhancement of hyperlipidemia and depression of high-density lipoprotein

1983 • 144 citations

Vitamin E content and low density lipoprotein oxidizability induced by free radicals

1990 • 137 citations

Vitamin C Concentration of Plasma and Leukocytes as Related to Smoking Habit, Age, and Sex of Humans

1968 • 125 citations

SMOKING AND THE HEART

1974 • 118 citations

Relationship of Plasma Level of Vitamin C to Mortality from Ischemic Heart Disease

1987 • 85 citations

Determination of several retinoids, carotenoids and E vitamers by high-performance liquid chromatography

1991 • 77 citations

In vivo catabolism of biologically modified LDL.

1984 • 74 citations

Effect of smoking on serum levels of HDL apoproteins

1979 • 53 citations

Determination of cotinine in biological fluids of non-smokers by packed column gas-liquid chromatography

1986 • 50 citations

Fluorimetric determination of menadione sodium bisulphite (vitamin K3) in animal feed and premixes by high-performance liquid chromatography with post-column derivatization

1984 • 37 citations

Atherosclerosis, Smoking and Other Risk Factors

1980 • 22 citations