Energy Metabolism and Brain Slice Function

Intracellular pH.

1981 • 2,440 citations

Effect of Ischemia on Known Substrates and Cofactors of the Glycolytic Pathway in Brain

1964 • 2,227 citations

Radioimmunoassay for Cyclic Nucleotides

1972 • 2,057 citations

Brain dopamine receptors.

1980 • 1,878 citations

Cell Damage in the Brain: A Speculative Synthesis

1981 • 1,827 citations

Brain energy metabolism

1978 • 1,448 citations

Cytosolic phosphorylation potential.

1979 • 906 citations

Biochemistry and the central nervous system

1986 • 794 citations

Ketone-body utilization by adult and suckling rat brain in vivo

1971 • 590 citations

Localization of Functional Activity in the Central Nervous System by Measurement of Glucose Utilization with Radioactive Deoxyglucose

1981 • 572 citations

Modulation of neurotransmission by purine nucleotides and nucleosides

1980 • 526 citations

Release of Adenosine from Ischemic Brain

1974 • 514 citations

An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. I. Magnitude and time course of degeneration

1976 • 453 citations

CEREBRAL CARBOHYDRATE METABOLISM DURING ACUTE HYPOXIA AND RECOVERY¹

1972 • 363 citations

ADENINE NUCLEOTIDES AND SYNAPTIC TRANSMISSION IN THE in vitro RAT HIPPOCAMPUS

1980 • 357 citations

Biochemistry and the Central Nervous System

1972 • 346 citations

Brain extracellular ion composition and EEG activity following 10 minutes ischemia in normo- and hyperglycemic rats.

1981 • 308 citations

Role of creatine phosphokinase in cellular function and metabolism

1978 • 298 citations

CEREBRAL BLOOD FLOW AND METABOLIC RATE EARLY AND LATE IN PROLONGED EPILEPTIC SEIZURES INDUCED IN RATS BY BICUCULLINE

1976 • 296 citations

Calcium‐mediated inactivation of the calcium conductance in caesium‐loaded giant neurones of Aplysia californica.

1981 • 288 citations

The transverse hippocampal slice: a well-defined cortical structure maintainedin vitro

1971 • 288 citations

Anoxia increases potassium conductance in hippocampal nerve cells

1982 • 262 citations

Mechanisms involved in irreversible anoxic damage to the in vitro rat hippocampal slice

1982 • 261 citations

Oxygen and glucose consumption related to Na+-K+ transport in canine brain.

1981 • 258 citations

Global Ischemia in Dogs: Intracranial Pressures, Brain Blood Flow and Metabolism

1975 • 254 citations

Calcium control of exocytosis and endocytosis in bovine adrenal medullary cells

1981 • 250 citations

THE EFFECT OF HYPERCAPNIA UPON INTRACELLULAR pH IN THE BRAIN, EVALUATED BY THE BICARBONATE‐ CARBONIC ACID METHOD AND FROM THE CREATINE PHOSPHOKINASE EQUILIBRIUM

1972 • 249 citations

Presynaptic failure of neuromuscular propagation in rats

1959 • 243 citations

Effects of pH on Na+-Ca2+ exchange in canine cardiac sarcolemmal vesicles.

1982 • 242 citations

Brain Edema: Induction in Cortical Slices by Polyunsaturated Fatty Acids

1978 • 242 citations

Brain Electrolytes and Fluid Metabolism.

1973 • 236 citations

Electrophysiology of isolated mammalian CNS preparations

1982 • 226 citations

Kinetic Studies on a Brain Microsomal Adenosine Triphosphatase. Evidence Suggesting Conformational Changes^*

1967 • 216 citations

The Influence of Arterial Hypoxemia upon Labile Phosphates and upon Extracellular and Intracellular Lactate and Pyruvate Concentrations in the Rat Brain

1971 • 215 citations

Adenine derivatives as neurohumoral agents in the brain. The quantities liberated on excitation of superfused cerebral tissues

1972 • 211 citations

CONCENTRATIONS OF ENERGY METABOLITES AND CYCLIC NUCLEOTIDES DURING AND AFTER BILATERAL ISCHEMIA IN THE GERBIL CEREBRAL CORTEX

1977 • 210 citations

Reduced ATP concentration as a basis for synaptic transmission failure during hypoxia in the in vitro guinea‐pig hippocampus

1982 • 208 citations

Cerebral metabolic state following complete compression ischemia

1974 • 204 citations

Relationship between adenosine concentration and oxygen supply in rat brain

1975 • 202 citations

The dependence of the respiration of brain cortex on active cation transport

1962 • 196 citations

Radioimmunoassay for Cyclic Nucleotides

1972 • 177 citations

Cellular mechanisms for calcium transfer and homeostasis

1971 • 170 citations

Interhippocampal Impulses

1960 • 169 citations

The in vitro brain slice as a useful neurophysiological preparation for intracellular recording

1980 • 166 citations

Effects of phenobarbital in cerebral ischemia. Part II: restitution of cerebral energy state, as well as of glycolytic metabolites, citric acid cycle intermediates and associated amino acids after pronounced incomplete ischemia.

1978 • 165 citations

The Role of Cyclic Nucleotides in the CNS

1977 • 163 citations

The effect of substances releasing intracellular calcium ions on sodium‐dependent calcium efflux from guinea‐pig auricles.

1975 • 163 citations

Cerebral metabolism in hypoxic hypoxia. I. Pattern of activation of glycolysis: a re-evaluation

1975 • 159 citations

Metabolic Changes in Cerebral Cortex, Hippocampus, and Cerebellum During Sustained Bicuculline‐Induced Seizures

1981 • 144 citations

Adenosine Receptor Agonists Inhibit K⁺‐Evoked Ca²⁺ Uptake by Rat Brain Cortical Synaptosomes

1982 • 142 citations

Graded Hypoxia-Oligemia in Rat Brain

1973 • 137 citations

Adenosine Receptors Mediating Cyclic AMP Productioin the Rat Hippocampus

1982 • 137 citations

Control of glycolysis in cerebral cortex slices

1967 • 131 citations

Calculated Equilibria of Phosphocreatine and Adenosine Phosphates during Utilization of High Energy Phosphate by Muscle

1974 • 130 citations

The Effect of Arterial Hypotension upon the Lactate, Pyruvate and Bicarbonate Concentrations of Brain Tissue and Cisternal CSF, and upon the Tissue Concentrations of Phosphocreatine and Adenine Nucleotides in Anesthetized Rats

1970 • 129 citations

Effects of Anoxia on the Stimulated Release of Amino Acid Neurotransmitters in the Cerebellum In Vitro

1983 • 127 citations

Cerebral Oxidative Metabolism and Blood Flow During Acute Hypoglycemia and Recovery in Unanesthetized Rats

1982 • 121 citations

The effect of hypoxia on evoked potentials in the in vitro hippocampus.

1979 • 119 citations

The localization of the MM isozyme of creatine phosphokinase on the surface membrane of myocardial cells and its functional coupling to ouabain-inhibited (Na+,K+)-ATPase

1977 • 108 citations

Decreases in Amino Acid and Acetylcholine Metabolism During Hypoxia

1981 • 107 citations

Brain Energy Metabolism

1979 • 107 citations

On the preparation of brain slices: morphology and cyclic nucleotides

1979 • 107 citations

Dopamine action on hippocampal pyramidal cells

1982 • 105 citations

Cerebral Synaptic Transmission During Anoxia Is Protected by Creatine

1981 • 100 citations

Ca²⁺ and Calmodulin‐Dependent Phosphorylation of Endogenous Synaptic Vesicle Tubulin by a Vesicle‐Bound Calmodulin Kinase System

1982 • 98 citations

Cortical CO₂ tension and neuronal excitability

1965 • 97 citations

THE SODIUM, POTASSIUM AND CHLORIDE OF CEREBRAL TISSUES: MAINTENANCE, CHANGE ON STIMULATION AND SUBSEQUENT RECOVERY

1965 • 96 citations

Intracellular pH of brain: alterations in acute respiratory acidosis and alkalosis

1976 • 91 citations

Incomplete versus complete cerebral ischemia: Improved outcome with a minimal blood flow

1979 • 89 citations

The effect of depressants on the metabolism of stimulated cerebral tissues

1953 • 85 citations

The Effect of Asphyxia upon the Lactate, Pyruvate and Bicarbonate Concentrations of Brain Tissue and Cisternal CSF, and upon the Tissue Concentrations of Phosphocreatine and Adenine Nucleotides in Anesthetized Rats

1970 • 84 citations

ATPase and carbonic anhydrase activities of bulk-isolated neuron, glia and synaptosome fractions from rat brain

1978 • 84 citations

Limiting section thickness of guinea pig olfactory cortical slices studied from tissuepO2 values and electrical activities

1982 • 83 citations

FLUID COMPARTMENTATION AND ELECTROLYTES OF CAT CEREBRAL CORTEX IN VITRO–II SODIUM, POTASSIUM AND CHLORIDE OF MATURE CEREBRAL CORTEX

1966 • 83 citations

THE EFFECT OF EXTRACELLULAR POTASSIUM CONCENTRATION ON PROTEIN SYNTHESIS IN GUINEA‐PIG HIPPOCAMPAL SLICES^1,2

1977 • 76 citations

The preservation of nerve cells in rat neostriatal slices maintained in vitro: A morphological study

1980 • 75 citations

Induced optical activity of the metarhodopsins

1971 • 75 citations

Energy Metabolism in Rat Brain Synaptosomes from Nembutal‐Anesthetized and Nonanesthetized Animals

1980 • 68 citations

Energiestoffwechsel der Gro�hirnrinde und Elektrencephalogramm bei Sauerstoffmangel

1966 • 66 citations

The sodium and other ions of mammalian cerebral tissues, maintained and electrically stimulated in vitro

1962 • 64 citations

THE CATIONIC COMPOSITION OF INCUBATED CEREBRAL CORTEX SLICES

1968 • 57 citations

Studies on the mitochondrially bound form of rat brain creatine kinase

1978 • 56 citations

Dependence of the viability of neurons in hippocampal slices on oxygen supply

1982 • 54 citations

Cerebral oxygen consumption and blood flow in hypoxia: influence of sympathoadrenal activation.

1979 • 54 citations

Synaptic potentials recorded in brain slices and their modification by changes in the level of tissue ATP

1970 • 52 citations

DEVELOPMENT OF (Na⁺‐K⁺)‐ATPase IN RAT CEREBRUM: CORRELATION WITH Na ⁺ ‐DEPENDENT PHOSPHORYLATION AND K ⁺‐para NITROPHENYLPHOSPHATASE¹

1978 • 50 citations

Inhibitory action of adenosine, 5-HT (serotonin) and GABA (γ-aminobutyric acid) on the postsynaptic potential (PSP) of slices from olfactory cortex and superior colliculus in correlation to the level of cyclic AMP

1979 • 49 citations

Parallel investigations of the effects of adenosine on evoked potentials and cyclic AMP accumulation in hippocampus slices of the rat

1979 • 47 citations

The interaction of pH and divalent cations at the neuromuscular junction.

1975 • 47 citations

EFFECTS OF ELECTRICAL STIMULATION ON METABOLITES IN BRAIN OF DECAPITATED MICE

1967 • 44 citations

Postischemic Cerebral Blood Flow and Oxygen Utilization Rate in Rats Anesthetized with Nitrous Oxide or Phenobarbital

1977 • 44 citations

Regulation of glycolytic flux in an energetically controlled cell-free system: The effects of adenine nucleotide ratios, inorganic phosphate, pH, and citrate

1981 • 44 citations

Intracellular pH of the Brain in Arterial Hypoxemia, Evaluated with the CO₂Method and from the Creatine Phosphokinase Equilibrium

1972 • 43 citations

Carbon Dioxide Effects on Nerve Cell Function

1974 • 43 citations

Factors affecting the free fatty acids in rat brain cortex

1982 • 43 citations

Creatine and the control of energy metabolism in cardiac and skeletal muscle cells in culture

1974 • 41 citations

The "late" Ca channel in squid axons.

1981 • 41 citations

Intracellular adjustments of skeletal muscle, heart, and brain to prolonged hypercapnia

1973 • 39 citations

Regulation of energy metabolism by creatine in cardiac and skeletal muscle cells in culture

1976 • 38 citations

Extracellular and intracellular distribution of inulin in rat brain cortex slices

1974 • 38 citations

The composition of isolated cerebral tissue: purines

1957 • 34 citations

Modulation of an inhibitory circuit by adenosine and AMP in the hippocampus

1982 • 32 citations

MECHANISM OF EXTRACELLULAR POTASSIUM STIMULATION OF PROTEIN SYNTHESIS IN THE IN VITRO HIPPOCAMPUS¹

1978 • 32 citations

The Effects of Acute Carbon Monoxide Intoxication on the Cerebral Energy Metabolism of the Rat

1975 • 31 citations

Effects of Hypoxia of 10–45 Seconds Duration on Energy Metabolism in the Cerebral Cortex of Unanesthetized and Anesthetized Rats

1975 • 31 citations

Heart Creatine Kinase, The Integration of Isozymes for Energy Distribution

1981 • 31 citations

Control of aerobic glycolysis in the brain in vitro

1980 • 28 citations

The effects of ATP on the interactions between monovalent cations and the sodium pump in dialysed squid axons

1981 • 27 citations

The composition of isolated cerebral tissues: creatine

1956 • 27 citations

Pancreatic acinar cell function: measurement of intracellular ions and pH and their relation to secretion.

1981 • 25 citations

Regulation of nerve terminal calcium channel selectivity by a weak acid site

1979 • 25 citations

Regional changes in cerebellar creatine phosphate metabolism during late maturation

1973 • 24 citations

ACTIVATION OF GLYCOGEN PHOSPHORYLASE IN RAT CAUDATE NUCLEUS SLICES BY l-ISOPROPYLNOREPINEPHERINE AND DIBUTYRYL CYCLIC AMP

1977 • 24 citations

Attenuation of Brain Free Fatty Acid Liberation during Global Ischemia: A Model for Screening Potential Therapies for Efficacy?

1982 • 23 citations

Comparison of extracellular space in the mature and ageing rat brain using a new technique

1982 • 23 citations

On the fractionation of agglutinins and antitoxin

1906 • 22 citations

Estimation of Ionic Concentrations and Intracellular pH in Slices from Different Areas of Rat Brain

1970 • 21 citations

Distribution of inulin, sucrose and mannitol in rat brain cortex slices following in vivo or in vitro equilibration

1979 • 21 citations

The action of carbon dioxide on synaptic transmission in the cuneate nucleus

1971 • 20 citations

The coupling of the adenylate kinase and creatine kinase equilibria. Calculation of substrate and feedback signal levels in muscle

1970 • 20 citations

Heart creatine kinase : the integration of isozymes for energy distribution

1980 • 18 citations

Brain Electrolytes and Fluid Metabolism

1973 • 16 citations

On the measurement of extracellular space in slices prepared from different rat brain areas

1973 • 16 citations

Electrolyte‐ and fluid‐spaces of rat brain in situ after infusion with dinitrophenol

1975 • 14 citations

The site of anoxic block in the spinal monosynaptic pathway

1975 • 13 citations

Role of diffusion of oxygen in the respiration of tissues at different temperatures

1965 • 11 citations

The dependence of water content and ?extracellular? marker spaces of incubated mouse brain slices on thickness

1974 • 10 citations

A CALCIUM PUMP IN RED CELL MEMBRANES

1971 • 9 citations

Untitled

1976 • 8 citations

Extracellular K+ and H+ Activities in the Brain Cortex During and after a Short Period of Ischaemia and Arterial Hypoxia

1978 • 8 citations