Ca²⁺ and Calmodulin‐Dependent Phosphorylation of Endogenous Synaptic Vesicle Tubulin by a Vesicle‐Bound Calmodulin Kinase System

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

Calmodulin Plays a Pivotal Role in Cellular Regulation

1980 • 2,441 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release.

1979 • 1,408 citations

The separation of synaptic vesicles from nerve-ending particles (‘synaptosomes’)

1964 • 1,213 citations

Cell Communication, Calcium Ion, and Cyclic Adenosine Monophosphate

1970 • 1,097 citations

The dependence of contraction and relaxation of muscle fibres from the crab Maia squinado on the internal concentration of free calcium ions

1964 • 1,034 citations

Calmodulin

1980 • 982 citations

The role of calcium in the release of neurotransmitter substances and hormones.

1970 • 871 citations

Relationships between calcium and cyclic nucleotides in cell activation.

1977 • 849 citations

Cyclic Nucleotide-dependent Protein Kinases

1969 • 551 citations

Identification of a calcium-binding protein as a calcium-dependent regulator of brain adenylate cyclase.

1975 • 546 citations

Antiepileptic drugs : mechanisms of action

1980 • 508 citations

Modulator protein as a component of the myosin light chain kinase from chicken gizzard

1978 • 488 citations

Structural changes after transmitter release at the frog neuromuscular junction.

1981 • 471 citations

Transmitter release induced by injection of calcium ions into nerve terminals

1973 • 443 citations

Adenosine 3':5'-monophosphate-regulated phosphoprotein system of neuronal membranes. I. Solubilization, purification, and some properties of an endogenous phosphoprotein.

1977 • 411 citations

Cyclic 3′ : 5′-Nucleotide Phosphodiesterase

1974 • 381 citations

Protein activator of cyclic 3′:5′-nucleotide phosphodiesterase of bovine or rat brain also activates its adenylate cyclase

1975 • 361 citations

Stimulation of Ca ²⁺ -dependent neurotransmitter release and presynaptic nerve terminal protein phosphorylation by calmodulin and a calmodulin-like protein isolated from synaptic vesicles

1979 • 346 citations

Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein

1978 • 332 citations

Presynaptic calcium currents and their relation to synaptic transmission: Voltage clamp study in squid giant synapse and theoretical model for the calcium gate

1976 • 323 citations

Identification of an activator protein for myosin light chain kinase as the Ca2+-dependent modulator protein.

1978 • 311 citations

Microtubules

1978 • 289 citations

Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide.

1978 • 264 citations

Inhibition of microtubule assembly by phosphorylation of microtubule-associated proteins

1980 • 245 citations

Subcellular Distribution of Adenosine 3',5'-Monophosphate-dependent Protein Kinase in Rat Brain

1971 • 208 citations

Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase.

1979 • 200 citations

Proteins of the nervous system

1973 • 180 citations

Calmodulin in neurotransmitter release and synaptic function.

1982 • 172 citations

Evidence for three distinct forms of calmodulin‐dependent protein kinases from rat brain

1980 • 166 citations

The calmodulin hypothesis of neurotransmission

1981 • 161 citations

Muscle-Like Contractile Proteins and Tubulin in Synaptosomes

1974 • 158 citations

Tubulin: An Integral Protein of Mammalian Synaptic Vesicle Membranes

1980 • 156 citations

MICROTUBULE PROTEIN

1971 • 153 citations

Rat Brain Tubulin and Protein Kinase Activity

1974 • 131 citations

Ca2+- and calmodulin-stimulated endogenous phosphorylation of neurotubulin.

1981 • 126 citations

ROLE OF CALMODULIN IN NEUROTRANSMITTER RELEASE AND SYNAPTIC FUNCTION*

1980 • 125 citations

Benzodiazepine Inhibition of the Calcium-Calmodulin Protein Kinase System in Brain Membrane

1981 • 115 citations

Calcium dependent neurotransmitter release and protein phosphorylation in synaptic vesicles

1978 • 109 citations

Regulation of Protein Phosphorylation and Membrane Permeability by b-Adrenergic Agents and Cyclic Adenosine 3':5'-Monophosphate in the Avian Erythrocyte

1974 • 109 citations

Endogenous protein kinase inhibitors. Purification, characterization, and distribution in different tissues.

1977 • 92 citations

Identification of endogenous substrate proteins for cAMP-dependent protein kinase in bovine brain.

1980 • 90 citations

Calcium-dependent phosphorylation of specific synaptosomal fraction proteins: Possible role of phosphoproteins in mediating neurotransmitter release

1976 • 82 citations

ISOLATION OF COATED VESICLES, PLAIN SYNAPTIC VESICLES, AND FLOCCULENT MATERIAL FROM A CRUDE SYNAPTOSOME FRACTION OF GUINEA PIG WHOLE BRAIN

1973 • 73 citations

Phosphorylation and dephosphorylation of membrane proteins as a possible mechanism for structural rearrangement of membrane components

1976 • 72 citations

Calcium-dependent phosphorylation of synaptic vesicle proteins and its possible role in mediating neurotransmitter release and vesicle function

1977 • 62 citations

REGULATION OF THE LEVEL OF ENDOGENOUS PHOSPHORYLATION OF SPECIFIC BRAIN PROTEINS BY DIPHENYLHYDANTOIN¹

1977 • 59 citations

Activation of phosphorylase kinase from brain by small amounts of calcium ion

1973 • 59 citations

CALCIUM DEPENDENT REGULATION OF BRAIN AND CARDIAC MUSCLE ADENYLATE CYCLASE*

1980 • 51 citations

Topological organization of proteins in an intracellular secretory organelle: the synaptic vesicle.

1979 • 50 citations

ENZYMATIC ACTIVITY IN TUBULIN PREPARATIONS: CYCLIC‐AMP DEPENDENT PROTEIN KINASE ACTIVITY OF BRAIN MICROTUBULE PROTEIN¹

1975 • 50 citations

Ca2+ and calmodulin-regulated endogenous tubulin kinase activity in presynaptic nerve terminal preparations

1982 • 50 citations

Antagonistic action of diphenylhydantoin and calcium on the level of phosphorylation of particular rat and human brain proteins

1977 • 47 citations

Effect of diphenylhydantoin on the endogenous phosphorylation of brain protein

1976 • 31 citations

The calibration and use of a calcium ion-specific electrode for kinetic studies of mitochondrial calcium transport

1979 • 22 citations

Stimulus secretion coupling in vitro: A rapid perfusion apparatus for monitoring efflux of transmitter substances from tissue samples

1975 • 20 citations

Calcium, Calmodulin, and Synaptic Function: Modulation of Neurotransmitter Release, Nerve Terminal Protein Phosphorylation, and Synaptic Vesicle Morphology by Calcium and Calmodulin

1981 • 13 citations

Two‐dimensional analysis of autophosphorylated chick brain synaptic subfractions

1980 • 5 citations