The in vitro brain slice as a useful neurophysiological preparation for intracellular recording

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

Handbook of Psychopharmacology

1988 • 2,778 citations

Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system.

1934 • 1,982 citations

Electric current flow in excitable cells

1976 • 1,353 citations

The neurosciences. Fourth study program

1980 • 1,165 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the unanaesthetized rabbit following stimulation of the perforant path

1973 • 1,140 citations

Lamellar organization of hippocampal excitatory pathways

1971 • 914 citations

The Structure and Function of Nervous Tissue

1972 • 905 citations

Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells

1978 • 745 citations

The mechanism of excitation by acetylcholine in the cerebral cortex

1971 • 698 citations

Physiology of the cerebro-spinal fluid

1967 • 622 citations

Opioid Peptides May Excite Hippocampal Pyramidal Neurons by Inhibiting Adjacent Inhibitory Interneurons

1979 • 610 citations

Unit analysis of hippocampal population spikes

1971 • 608 citations

Heterosynaptic depression: a postsynaptic correlate of long-term potentiation

1977 • 606 citations

Theory of Physiological Properties of Dendrites

1962 • 586 citations

A calcium-activated hyperpolarization follows repetitive firing in hippocampal neurons

1980 • 576 citations

Intradendritic recordings from hippocampal neurons.

1979 • 560 citations

Characteristics of CA1 neurons recorded intracellularly in the hippocampalin vitro slice preparation

1975 • 508 citations

Long-term potentiation of the perforant path-granule cell synapse in the rat hippocampus

1975 • 501 citations

Specific long-lasting potentiation of synaptic transmission in hippocampal slices

1977 • 493 citations

Two different responses of hippocampal pyramidal cells to application of gamma‐amino butyric acid.

1980 • 489 citations

Long‐term potentiation and depression of synaptic responses in the rat hippocampus: localization and frequency dependency.

1978 • 470 citations

LOCATION OF POSTSYNAPTIC INHIBITORY SYNAPSES ON HIPPOCAMPAL PYRAMIDS

1964 • 462 citations

An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. I. Magnitude and time course of degeneration

1976 • 453 citations

Long-term and short-term plasticity in the CA1, CA3, and dentate regions of the rat hippocampal slice

1976 • 444 citations

Cellular and field potential properties of epileptogenic hippocampal slices

1978 • 438 citations

Depressant action of TRH, LH-RH and somatostatin on activity of central neurones

1975 • 427 citations

Participation of calcium spikes during intrinsic burst firing in hippocampal neurons

1978 • 425 citations

ELECTRICAL ACTIVITIES IN THIN SECTIONS FROM THE MAMMALIAN BRAIN MAINTAINED IN CHEMICALLY‐DEFINED MEDIA IN VITRO

1966 • 395 citations

Neurophysiology of Epilepsy

1978 • 391 citations

Prolongation of hippocampal inhibitory postsynaptic potentials by barbiturates

1975 • 375 citations

A simple perfusion chamber for the study of nervous tissue slices in vitro

1979 • 368 citations

Long-lasting facilitation of a synaptic potential following tetanization in thein vitro hippocampal slice

1975 • 340 citations

Advances in Epileptology

1988 • 337 citations

GABA-mediated biphasic inhibitory responses in hippocampus

1979 • 332 citations

Physiological and morphological identification of a nonpyramidal hippocampal cell type

1978 • 332 citations

Role of Muscarinic Cholinergic Receptors in Regulation of Guanosine 3′:5′-Cyclic Monophosphate Content in Mammalian Brain, Heart Muscle, and Intestinal Smooth Muscle

1972 • 327 citations

Dual mode of synaptic transmission in the avian ciliary ganglion

1963 • 326 citations

Pharmacological properties of acetylcholine‐sensitive cells in the cerebral cortex

1963 • 321 citations

Physiology of the Cerebrospinal Fluid

1967 • 319 citations

Dendritic Mechanisms Underlying Penicillin-Induced Epileptiform Activity

1979 • 312 citations

Probable calcium spikes in hippocampal neurons

1977 • 301 citations

Aspartate and glutamate as possible transmitters of excitatory hippocampal afferents

1976 • 300 citations

The transverse hippocampal slice: a well-defined cortical structure maintainedin vitro

1971 • 288 citations

Transient Response in a Dendritic Neuron Model for Current Injected at One Branch

1974 • 278 citations

Practical Neurochemistry

1963 • 272 citations

Actions of gamma‐aminobutyric acid on sympathetic ganglion cells.

1975 • 269 citations

Is somatostatin an excitatory transmitter in the hippocampus?

1978 • 262 citations

Measurement of extracellular potassium activity in cat cortex

1973 • 248 citations

Anomalous inward rectification in hippocampal neurons

1979 • 248 citations

The excitatory action of acetylcholine on hippocampal neurones of the guinea pig and rat maintained in vitro

1981 • 244 citations

Hippocampal pyramidal cells: significance of dendritic ionic conductances for neuronal function and epileptogenesis

1979 • 244 citations

Activation of hippocampal neurons by mossy fiber stimulation in thin brain sections in vitro

1972 • 243 citations

Excitation of mammalian central neurones by acidic amino acids

1972 • 239 citations

Voltage clamping with a single microelectrode

1975 • 238 citations

Abnormal Neuronal Discharges

1979 • 235 citations

Actions of glutamic acid on spinal neurones

1973 • 234 citations

Synaptic excitation and inhibition resulting from direct action of acetylcholine on two types of chemoreceptors on individual amphibian parasympathetic neurones

1977 • 233 citations

Penicillin‐induced epileptiform activity in the hippocampal in vitro preparation

1977 • 231 citations

Reduced inhibition during epileptiform activity in the in vitro hippocampal slice.

1980 • 223 citations

A study on the mechanism of impulse transmission across the giant synapse of the squid

1958 • 218 citations

STUDIES OF THE INTER‐RELATIONSHIP BETWEEN CEREBROSPINAL FLUID AND PLASMA AMINO ACID CONCENTRATIONS IN NORMAL INDIVIDUALS

1977 • 216 citations

Local synaptic circuits in rat hippocampus: interactions between pyramidal cells

1980 • 214 citations

Detachment of structurally intact nerve endings from chromatolytic neurones of rat superior cervical ganglion during the depression of synaptic transmission induced by post‐ganglionic axotomy.

1975 • 207 citations

Depressant actions of methionine-enkephalin and somatostatin in cat dorsal horn neurones activated by noxious stimuli

1978 • 200 citations

CSF amino acids and plasma‐CSF amino acid ratios in adults¹

1975 • 195 citations

Organization of the hippocampal output

1973 • 187 citations

Functional characteristics of unmyelinated fibres in the hippocampal cortex

1978 • 184 citations

Effect of H+ on spontaneous neuronal activity in the surface layer of the rat medulla oblongata in vitro

1977 • 181 citations

Na, K, Ca, Mg, AND Cl CONCENTRATIONS IN CHOROID PLEXUS FLUID AND CISTERNAL FLUID COMPARED WITH PLASMA ULTRAFILTRATE

1964 • 173 citations

Maintenance of resting membrane potentials in slices of mammalian cerebral cortex and other tissues in vitro

1957 • 171 citations

Cellular biology of neurons

1977 • 167 citations

Iontophoresis and transmitter mechanisms in the mammalian central nervous system

1979 • 158 citations

Calcium, magnesium and the electrical activity of guinea‐pig olfactory cortex in vitro

1970 • 149 citations

The actions of excitatory amino acids on motoneurones in the feline spinal cord.

1979 • 147 citations

A pressure system for intracellular and extracellular ejections of picoliter volumes

1977 • 145 citations

Ion movements in junctional transmission.

1967 • 135 citations

The Role of Extracellular Potassium in Hippocampal Epilepsy

1976 • 131 citations

Central actions of somatostatin

1980 • 130 citations

Membrane potentials in mammalian cerebral tissues in vitro: dependence on ionic environment

1961 • 122 citations

Electrical activity observed in guinea‐pig olfactory cortex maintained in vitro

1968 • 122 citations

The effect of hypoxia on evoked potentials in the in vitro hippocampus.

1979 • 119 citations

Penicillin blocks hippocampal IPSPs, unmasking prolonged EPSPs

1979 • 117 citations

Microphysiology of human cerebral cortex studied in vitro

1976 • 116 citations

Specific release of endogenous glutamate from piriform cortex stimulated in vitro

1976 • 112 citations

Continuous recording of changes in membrane potential in mammalian cerebral tissues in vitro; recovery after depolarization by added substances

1965 • 110 citations

GDEE antagonism of iontophoretic amino acid excitations in the intact hippocampus and in the hippocampal slice preparation

1976 • 108 citations

Effect of magnesium ions on the responses of spinal neurones to excitatory amino acids and acetylcholine

1977 • 108 citations

CHARACTERIZATION OF PUTATIVE AMINO ACID TRANSMITTER RELEASE FROM SLICES OF RAT DENTATE GYRUS

1977 • 107 citations

On the preparation of brain slices: morphology and cyclic nucleotides

1979 • 107 citations

Intracellular study of seizure-like afterdischarges elicited in thin hippocampal sections in vitro

1972 • 106 citations

Synaptic delay in the heart: an ionophoretic study.

1978 • 105 citations

Conductance changes and inhibitory actions of hippocampal recurrent IPSPs

1980 • 101 citations

Calcium dependance of synaptic transmission in the hippocampal slice

1981 • 101 citations

Microelectrophoretic studies concerning the spread of glutamic acid and GABA in brain tissue

1969 • 99 citations

Electrical properties of neurones in the olfactory cortex slice in vitro.

1978 • 98 citations

Spontaneous and osmotically-stimulated activity in slices of rat hypothalamus

1978 • 97 citations

The effect of acidic amino acid antagonists on synaptic transmission in the hippocampal formation in vitro

1979 • 95 citations

The action of noradrenaline on cortical neurons: effects of pH

1971 • 93 citations

Effect of somatostatin (SRIF) and L-glutamate on neurons of the sensorimotor cortex in awake habituated rabbits

1978 • 93 citations

Mechanisms of post‐synaptic excitation in amphibian motoneurones.

1978 • 87 citations

Long term potentiation is accompanied by a reduction in dendritic responsiveness to glutamic acid

1976 • 85 citations

Hippocampal Lesions Following Administration of 3-Acetylpyridine

1958 • 84 citations

Anatomical evidence for interlamellar inhibition in the fascia dentata

1978 • 83 citations

A depolarizing inhibitory potential in neurones of the olfactory cortex in vitro.

1978 • 82 citations

Sensitivity of Purkinje cell dendrites to glutamic acid

1975 • 81 citations

Glutamic acid sensitivity of dendrites in hippocampal slices in vitro.

1975 • 80 citations

Spontaneous miniature synaptic potentials in hippocampal neurons

1979 • 80 citations

Electrical changes in the membrane in junctional transmission

1973 • 77 citations

Controlled micro release of pharmacological agents: Measurements of volume ejected in vitro through fine tipped glass microelectrodes by pressure

1979 • 76 citations

Conductance changes associated with the secretory potential in the cockroach salivary gland

1974 • 75 citations

Stimulus evoked increase in the biosynthesis of the putative neurotransmitters glutamate in the hippocampus

1978 • 71 citations

Intracellular recording from visually identified motoneurons in rat spinal cord slices

1978 • 69 citations

Divalent cations and electrical properties of cortical cells

1969 • 68 citations

The Interpretation of Current-Voltage Relations Recorded from a Spherical Cell with a Single Microelectrode

1972 • 68 citations

Lamellar organisation in the rat hippocampus

1977 • 68 citations

MUSCARINIC EXCITATION: A MICROELECTROPHORETIC STUDY ON CULTURED SMOOTH MUSCLE CELLS

1974 • 68 citations

EFFECT OF STIMULATION OF EXCITATORY NERVE TRACT ON RELEASE OF GLUTAMIC ACID FROM OLFACTORY CORTEX SLICES IN VITRO

1976 • 67 citations

Locally evoked potentials in slices of rat neostriatum: A tool for the investigation of intrinsic excitatory processes

1979 • 67 citations

Analysis of catecholamine effects in single atrial trabeculae of the frog heart

1977 • 65 citations

DEPOLARIZATION OF NEURONES IN THE ISOLATED OLFACTORY CORTEX OF THE GUINEA-PIG BY γ-AMINOBUTYRIC ACID

1979 • 65 citations

Evoked surface-positive potentials in isolated mammalian olfactory cortex

1974 • 64 citations

Characterization of drug iontophoresis with a fast microassay technique

1976 • 64 citations

Field potentials, inhibition and the effect of pentobarbitone in the rat olfactory cortex slice.

1978 • 62 citations

Acute Effects of Methoxypyridoxine on Hippocampal End-Blade Neurons; An Experimental Study of “Special Pathoclisis” in the Cerebral Cortex

1960 • 60 citations

The correlation between extracellular potassium concentration and hippocampal epileptic activity in vitro

1976 • 55 citations

Cat spinal motoneurons exhibit topographic sensitivity to glutamate and glycine

1979 • 54 citations

GENERATION OF THE SEIZURE DISCHARGE IN THIN SECTIONS FROM THE GUINEA PIG BRAIN IN CHLORIDE-FREE MEDIUM IN VITRO

1968 • 50 citations

Intracellular studies on the action of L-glutamic acid on spinal neurones of the cat

1972 • 49 citations

Stimulation-dependent release of possible transmitter substances from hippocampal slices studied with localized perfusion

1979 • 47 citations

Delayed iontophoretic ejection of substance P from glass micropipettes: Correlation with time-course of neuronal excitation in vivo

1979 • 47 citations

Inhibition of firing of myenteric neurones by somatostatin

1978 • 46 citations

In vitro excitation of hippocampal pyramidal cell dendrites by glutamic acid

1974 • 45 citations

The action of N-methyl-D-aspartic and kainic acids on motoneurones with emphasis on conductance changes [proceedings].

1978 • 45 citations

The time course of cellular responses to iontophoretically applied drugs

1977 • 42 citations

A perfusion chamber for the study of CNS physiology and pharmacology in vitro

1978 • 41 citations

Action of amino acids and convulsants on cerebellar spontaneous action potentials in vitro: Effects of deprivation of Cl−, K+ or Na+

1976 • 40 citations

On the latency and form of the membrane responses of smooth muscle to the iontophoretic application of acetylcholine or carbachol

1976 • 40 citations

Activities of the sodium pump in cat pyramidal tract cells investigated with intracellular injection of sodium ions

1972 • 36 citations

Intracellular responses of rat dentate granule cellsin vitro: posttetanic potentiation to perforant path stimulation

1975 • 35 citations

EFFECTS OF AMINO ACIDS AND CONVULSANTS ON SPONTANEOUS ACTION POTENTIALS IN CEREBELLAR CORTEX SLICES

1976 • 33 citations

Ionic mechanisms of the depolarization shift in thin hippocampal slices

1975 • 33 citations

Phasic discharge in supraoptic neurones recorded from hypothalamic slices

1978 • 31 citations

Transynaptic transport of procion yellow in the central nervous system

1979 • 30 citations

Electrical activity recorded from thin sections of the lateral geniculate body, and the effects of 5-hydroxytryptamine

1974 • 29 citations

A potential screening technique for neurotransmitters in the CNS: Model studies in the cat spinal cord

1977 • 28 citations

Substance P causes direct depolarisation of neurones of guinea pig interpeduncular nucleus in vitro

1979 • 27 citations

The presence and nature of inhibition in small slices of the dorsal lateral geniculate nucleus of rat and cat incubated in vitro

1979 • 24 citations

Some effects of magnesium ions upon conduction and synaptic activity in the isolated spinal cord of the mouse

1979 • 22 citations

Effects ofγ-amino-butyric acid on the potentials evoked in vitro in the superior colliculus

1967 • 21 citations

Morphological features of physiologically identified hypothalamic neurons as revealed by intracellular marking

1979 • 19 citations

Intracellular recordings from hippocampal CA3 pyramidal cells during repetitive activation of the mossy fibers in vitro

1979 • 16 citations

Rate of offset of action of slow-acting muscarinic antagonists is fast

1977 • 16 citations

On the time course of the electrical response of salivary gland cells of Nauphoeta cinerea to ionophoretically applied dopamine.

1979 • 14 citations

Short lasting changes in hippocampal neuronal excitability following repetitive synaptic activation

1978 • 14 citations

EFFECTS OF N‐METHYLAMINO ACIDS AND CONVULSANTS ON SPONTANEOUS ACTION POTENTIALS IN GUINEA‐PIG CEREBELLAR SLICES

1977 • 13 citations

Proceedings: An improved chamber for maintaining mammalian brain tissue slices for electrical recording.

1974 • 12 citations

Topography and some characteristics of the dentate fascia-field CA3 relations investigated in hippocampal slices in vitro

1977 • 11 citations

Visualization of central neurons and recording of action potentials

1978 • 10 citations