Interaction of the S phase regulator Cdc18 with cyclin-dependent kinase in fission yeast

[56] Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

1991 • 3,691 citations

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

Human Cyclin E, a Nuclear Protein Essential for the G₁-to-S Phase Transition

1995 • 1,132 citations

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1994 • 902 citations

Regulation of p34cdc2 protein kinase during mitosis

1989 • 544 citations

Cell Cycle Control of DNA Replication

1996 • 512 citations

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation.

1996 • 485 citations

The fission yeast cdc18+ gene product couples S phase to START and mitosis

1993 • 446 citations

Comparison ofSchizosaccharomyces pombeexpression systems

1993 • 439 citations

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

1994 • 393 citations

The fission yeast cdc2/cdc13/suc1 protein kinase: Regulation of catalytic activity and nuclear localization

1989 • 392 citations

Efficient targeted integration at leu1-32 and ura4-294 in Schizosaccharomyces pombe.

1994 • 380 citations

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state

1995 • 366 citations

Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene

1994 • 356 citations

Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast.

1996 • 293 citations

p65cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast

1995 • 259 citations

Cyclin A-Associated Kinase Activity Is Rate Limiting for Entrance into S Phase and Is Negatively Regulated in G₁ by p27^Kip1

1995 • 252 citations

Conserved Initiator Proteins in Eukaryotes

1995 • 246 citations

Rapid Degradation of the G ₁ Cyclin Cln2 Induced by CDK-Dependent Phosphorylation

1996 • 227 citations

p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase

1995 • 190 citations

General purpose tagging vectors for fission yeast

1997 • 172 citations

Interaction of Cdc2 and CdclS with a fission yeast ORC2-like protein

1996 • 131 citations

cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.

1996 • 129 citations

Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.

1996 • 121 citations

B-type cyclins regulate G1 progression in fission yeast in opposition to the p25rum1 cdk inhibitor.

1996 • 115 citations

Cig2, a B-Type Cyclin, Promotes the Onset of S in Schizosaccharomyces pombe

1996 • 114 citations

Regulating S Phase: CDKs, Licensing and Proteolysis

1996 • 109 citations

Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex.

1995 • 98 citations

Rum1 and Cdc18 link inhibition of cyclin-dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe.

1996 • 96 citations

DNA replication: Controlling initiation during the cell cycle

1996 • 31 citations

Intracellular Location of theSaccharomyces cerevisiae CDC6Gene Product

1996 • 22 citations