PAF Produced by Human Breast Cancer Cells Promotes Migration and Proliferation of Tumor Cells and Neo-Angiogenesis

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

1998 • 2,440 citations

Macrophages and angiogenesis

1994 • 1,123 citations

Platelet-activating factor.

1990 • 904 citations

Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis.

1997 • 832 citations

Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung

1991 • 594 citations

Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor

1994 • 473 citations

Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool.

1995 • 441 citations

CV-3988 - A specific antagonist of platelet activating factor (PAF)

1983 • 341 citations

The molecular action of tumor necrosis factor-alpha

1991 • 279 citations

Cytokine networks in solid human tumors: regulation of angiogenesis

1994 • 209 citations

Characterization of a human cDNA that encodes a functional receptor for platelet activating factor

1991 • 179 citations

Expression of growth factors, growth inhibiting factors, and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loops

1998 • 175 citations

Tumor necrosis factor alpha-induced angiogenesis depends on in situ platelet-activating factor biosynthesis.

1994 • 149 citations

Bronchial hyperreactivity, increased endotoxin lethality and melanocytic tumorigenesis in transgenic mice overexpressing platelet-activating factor receptor

1997 • 139 citations

Role of thrombin receptor in breast cancer invasiveness

1999 • 114 citations

Pharmacologic activity of bepafant (WEB 2170), a new and selective hetrazepinoic antagonist of platelet activating factor.

1990 • 114 citations

Platelet-activating factor directly stimulates in vitro migration of endothelial cells and promotes in vivo angiogenesis by a heparin-dependent mechanism.

1995 • 108 citations

Purification of murine endothelial cell cultures by flow cytometry using fluorescein-labeled griffonia simplicifolia agglutinin.

1989 • 105 citations

Platelet activating factor produced in vitro by Kaposi's sarcoma cells induces and sustains in vivo angiogenesis.

1995 • 102 citations

Thrombopoietin Stimulates Endothelial Cell Motility and Neoangiogenesis by a Platelet-Activating Factor–Dependent Mechanism

1999 • 99 citations

Angiogenesis induced in vivo by hepatocyte growth factor is mediated by platelet-activating factor synthesis from macrophages.

1997 • 89 citations

Augmentation of tumor metastasis by platelet-activating factor.

1996 • 82 citations

PAF molecular heterogeneity: pathobiological implications.

1993 • 78 citations

Platelet-Activating Factor (PAF) Positively Auto-Regulates the Expression of Human PAF Receptor Transcript 1 (Leukocyte-Type) Through NF-κB

1994 • 64 citations

Potential Angiogenic Role of Platelet-Activating Factor in Human Breast Cancer

1998 • 64 citations

Platelet-Activating Factor Enhances Vascular Endothelial Growth Factor–Induced Endothelial Cell Motility and Neoangiogenesis in a Murine Matrigel Model

2000 • 62 citations

Effect of matrigel on the tumorigenicity of human breast and ovarian carcinoma cell lines

1996 • 57 citations

Platelet activating factor and human disease

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Effect of matrigel on the tumorigenicity of human breast and ovarian carcinoma cell lines

1996 • 53 citations

Platelet-activating factor antagonists.

1997 • 46 citations

Platelet Activating Factor Antagonists

1995 • 44 citations

Platelet-activating factor mediates an autocrine proliferative loop in the endometrial adenocarcinoma cell line HEC-1A.

1994 • 43 citations

Cobalt chloride-induced signaling in endothelium leading to the augmented adherence of sickle red blood cells and transendothelial migration of monocyte-like HL-60 cells is blocked by PAF-receptor antagonist

1999 • 39 citations

Presence of PAF-Acether in Human Breast Carcinoma: Relation to Axillary Lymph Node Metastasis

1989 • 32 citations

Platelet activating factor receptor (PAF-R) is found in a large endosomal compartment in human umbilical vein endothelial cells

1999 • 32 citations

Motility Induced by Human Immunodeficiency Virus-1 Tat on Kaposi's Sarcoma Cells Requires Platelet-Activating Factor Synthesis

1999 • 31 citations

Role of guanine nucleotide-binding protein and tyrosine kinase in platelet-activating factor activation of phospholipase C in A431 cells: proposal for dual mechanisms.

1993 • 24 citations

Platelet Activating Factor antagonists.

1998 • 22 citations

Implication of Protein Kinase Cα in PAF-Stimulated Phospholipase D Activation in Chinese Hamster Ovary (CHO) Cells Expressing PAF Receptor

1995 • 20 citations

Stimulation of platelet-activating factor (PAF) receptors increases inositol phosphate production and cytosolic free Ca2+ concentrations in N1E-115 neuroblastoma cells

1995 • 14 citations

Regulation of platelet‐activating factor production in gastric epithelial cells

1996 • 8 citations

Stimulation of intracellular free calcium increases by platelet-activating factor in HT29 colon carcinoma cells

1994 • 7 citations