Myocardial Structure and Function Differ in Systolic and Diastolic Heart Failure

Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial

2003 • 2,845 citations

Diastolic Heart Failure — Abnormalities in Active Relaxation and Passive Stiffness of the Left Ventricle

2004 • 1,457 citations

New Concepts in Diastolic Dysfunction and Diastolic Heart Failure: Part I

2002 • 1,170 citations

Combined Ventricular Systolic and Arterial Stiffening in Patients With Heart Failure and Preserved Ejection Fraction

2003 • 907 citations

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

2005 • 886 citations

The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus

2002 • 875 citations

Pathophysiological Characterization of Isolated Diastolic Heart Failure in Comparison to Systolic Heart Failure

2002 • 860 citations

Defining Diastolic Heart Failure

2000 • 735 citations

The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus

2002 • 732 citations

How to diagnose diastolic heart failure

1998 • 658 citations

How to diagnose diastolic heart failure

1998 • 604 citations

Enteroviral protease 2A cleaves dystrophin: Evidence of cytoskeletal disruption in an acquired cardiomyopathy

1999 • 553 citations

Progression of Systolic Abnormalities in Patients With “Isolated” Diastolic Heart Failure and Diastolic Dysfunction

2002 • 516 citations

Cardiomyocyte Stiffness in Diastolic Heart Failure

2005 • 513 citations

Heart Failure With a Normal Ejection Fraction

2001 • 489 citations

What Mechanisms Underlie Diastolic Dysfunction in Heart Failure?

2004 • 477 citations

Altered Titin Expression, Myocardial Stiffness, and Left Ventricular Function in Patients With Dilated Cardiomyopathy

2004 • 462 citations

CHARM INVESTIGATORS AND COMMITTEES. EFFECTS OF CANDESARTAN IN PATIENTS WITH CHRONIC HEART FAILURE AND PRESERVED LEFT-VENTRICULAR EJECTION FRACTION: THE CHARM-PRESERVED TRIAL

2003 • 458 citations

Epidemiology of Diastolic Heart Failure

2005 • 404 citations

Titin Isoform Switch in Ischemic Human Heart Disease

2002 • 368 citations

Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart

1999 • 360 citations

Left ventricular long axis function in diastolic heart failure is reduced in both diastole and systole: time for a redefinition?

2002 • 336 citations

Passive Stiffness Changes Caused by Upregulation of Compliant Titin Isoforms in Human Dilated Cardiomyopathy Hearts

2004 • 316 citations

Left Ventricular Systolic Performance, Function, and Contractility in Patients With Diastolic Heart Failure

2005 • 282 citations

Phosphorylation of Titin Modulates Passive Stiffness of Cardiac Muscle in a Titin Isoform-dependent Manner

2005 • 192 citations

Pressure- and Volume-Induced Left Ventricular Hypertrophies Are Associated With Distinct Myocyte Phenotypes and Differential Induction of Peptide Growth Factor mRNAs

1995 • 190 citations

Mechanisms of Exercise Intolerance

2004 • 188 citations

Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness.

2003 • 186 citations

Cardiac myocyte remodeling in hypertrophy and progression to failure

2002 • 137 citations

Contribution of left ventricular diastolic dysfunction to heart failure regardless of ejection fraction

2005 • 128 citations

Relation of various degrees of body mass index in patients with systemic hypertension to left ventricular mass, cardiac output, and peripheral resistance (The Hypertension Genetic Epidemiology Network Study)

2001 • 123 citations

Titin isoform expression in normal and hypertensive myocardium

2003 • 120 citations

Alcoholic cardiomyopathy and sudden cardiac death

1986 • 99 citations

Effects of Calcium, Inorganic Phosphate, and pH on Isometric Force in Single Skinned Cardiomyocytes From Donor and Failing Human Hearts

2001 • 98 citations

Glycated collagen cross-linking alters cardiac mechanics in volume-overload hypertrophy

2003 • 93 citations

Ventricular Structure and Function in Aged Dogs With Renal Hypertension

2005 • 79 citations

Isometric tension development and its calcium sensitivity in skinned myocyte-sized preparations from different regions of the human heart

1999 • 67 citations

Beta-adrenergic stimulation with isoproterenol enhances left ventricular diastolic performance in hypertrophic cardiomyopathy despite potentiation of myocardial ischemia. Comparison to rapid atrial pacing.

1989 • 59 citations

Myocardial Contractile Effects of Nitric Oxide

2006 • 27 citations

Myocardial contractile effects of nitric oxide.

2002 • 26 citations

Endomyocardial nitric oxide synthase and the hemodynamic phenotypes of human dilated cardiomyopathy and of athlete's heart

2002 • 23 citations

Modulation of Cardiac Function

2005 • 20 citations

Myocardial fibrosis blunts nitric oxide synthase-related preload reserve in human dilated cardiomyopathy

2003 • 15 citations

Deleted Work

1955 • 0 citations