Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Vascular endothelial growth factor (VEGF) and its receptors

1999 • 3,498 citations

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

1995 • 1,454 citations

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells.

1997 • 1,162 citations

Inducible nitric oxide synthase: what difference does it make?

1997 • 964 citations

Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis.

1997 • 924 citations

VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells

1998 • 694 citations

Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide.

1995 • 590 citations

Nitric Oxide Is an Upstream Signal of Vascular Endothelial Growth Factor-induced Extracellular Signal-regulated Kinase½ Activation in Postcapillary Endothelium

1998 • 436 citations

Role of Nitric Oxide in Angiogenesis and Tumor Progression in Head and Neck Cancer

1998 • 427 citations

Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages

1991 • 391 citations

Quantitative angiogenesis assays: Progress and problems

1997 • 386 citations

Reciprocal relation between VEGF and NO in the regulation of endothelial integrity

1997 • 367 citations

Synthesis, Storage, and Release of Vascular Endothelial Growth Factor/Vascular Permeability Factor (VEGF/VPF) by Human Mast Cells: Implications for the Biological Significance of VEGF₂₀₆

1998 • 339 citations

Mast cells are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangioma.

1995 • 311 citations

Production of Vascular Endothelial Growth Factor by Murine Macrophages

1998 • 304 citations

Inducible nitric oxide synthase‐deficient mice have enhanced leukocyte–endothelium interactions in endotoxemia

1997 • 298 citations

Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity

1995 • 274 citations

Carbon Monoxide and Nitric Oxide Suppress the Hypoxic Induction of Vascular Endothelial Growth Factor Gene via the 5′ Enhancer

1998 • 228 citations

Nitric oxide synthases

1996 • 222 citations

Nitric Oxide Promotes Proliferation and Plasminogen Activator Production by Coronary Venular Endothelium Through Endogenous bFGF

1997 • 211 citations

Controlling the vasculature: Angiogenesis, anti-angiogenesis and vascular targeting of gene therapy

1995 • 194 citations

Inhibition of angiogenesis, tumour growth and metastasis by the NO‐releasing vasodilators, isosorbide mononitrate and dinitrate

1995 • 156 citations

Nitric Oxide Promotes DNA Synthesis and Cyclic GMP Formation in Endothelial Cells from Postcapillary Venules

1993 • 125 citations

Vascular endothelial growth factor and nitric oxide synthase expression in human lung cancer and the relation to p53

1998 • 124 citations

Nitric oxide is involved in the regulation of angiogenesis

1993 • 105 citations

Prevention of the Expression of Inducible Nitric Oxide Synthase by Aminoguanidine or Aminoethyl-Isothiourea in Macrophages and in the Rat

1996 • 80 citations

Effect of NO, vasodilator prostaglandins, and adenosine on skeletal muscle angiogenic growth factor gene expression

1999 • 70 citations

Fas (CD95, APO-1) antigen expression and function in murine mast cells.

1997 • 44 citations

Involvement of nitric oxide in the inhibition of angiogenesis by interleukin‐2

1997 • 42 citations

Substance P increases cyclic GMP levels on coronary postcapillary venular endothelial cells

1993 • 39 citations

A model of bridging angiogenesis in the rat

1998 • 17 citations