Production of Vascular Endothelial Growth Factor by Murine Macrophages

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Interleukin-8 as a Macrophage-Derived Mediator of Angiogenesis

1992 • 2,130 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

Macrophages and angiogenesis

1994 • 1,123 citations

Transcriptional Regulation of the Rat Vascular Endothelial Growth Factor Gene by Hypoxia

1995 • 1,087 citations

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

1990 • 1,062 citations

L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

1987 • 958 citations

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.

1992 • 900 citations

Activated macrophages induce vascular proliferation

1977 • 818 citations

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

1987 • 718 citations

Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo.

1995 • 710 citations

Oxygen Tension Regulates the Expression of Angiogenesis Factor by Macrophages

1983 • 689 citations

Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.

1994 • 584 citations

Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells.

1989 • 568 citations

Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis.

1993 • 534 citations

Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue.

1994 • 524 citations

Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids.

1996 • 495 citations

Pertussis toxin-catalyzed ADP-ribosylation of transducin. Cysteine 347 is the ADP-ribose acceptor site.

1985 • 457 citations

Mechanism of action of choleragen. Evidence for ADP-ribosyltransferase activity with arginine as an acceptor.

1977 • 391 citations

Nitric oxide-induced S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase inhibits enzymatic activity and increases endogenous ADP-ribosylation.

1992 • 390 citations

Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages.

1984 • 366 citations

Hypoxic Induction of Endothelial Cell Growth Factors in Retinal Cells: Identification and Characterization of Vascular Endothelial Growth Factor (VEGF) as the Mitogen

1995 • 357 citations

Activation of a Cytosolic ADP-ribosyltransferase by Nitric Oxide-generating Agents

1989 • 349 citations

The Mouse Gene for Vascular Endothelial Growth Factor

1996 • 335 citations

Macrophage-derived angiogenesis factors

1991 • 325 citations

Hypoxia Is a Strong Inducer of Vascular Endothelial Growth Factor mRNA Expression in the Heart

1993 • 308 citations

Human Vascular Permeability Factor

1989 • 282 citations

Regulation of tumor necrosis factor/cachectin and IL-1 secretion in human mononuclear phagocytes.

1988 • 278 citations

The Pathophysiology of Angiogenesis

1995 • 269 citations

Expression of mRNA for vascular endothelial growth factor in human placenta

1993 • 245 citations

Bone formation and repair

1998 • 217 citations

Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism.

1994 • 205 citations

Role of vascular endothelial growth factor in angiogenesis of rheumatoid arthritis.

1995 • 172 citations

Secretion of oxygen intermediates: role in effector functions of activated macrophages.

1982 • 146 citations

Properties of Pro‐Inflammatory Cell Type‐Specific Leukocyte Chemotactic Cytokines, Interleukin 8 (IL‐8) and Monocyte Chemotactic and Activating Factor (MCAF)

1992 • 135 citations

Angiogenic macrophages produce the angiogenic inhibitor thrombospondin 1.

1993 • 111 citations

Induction of Neovascularization by Activated Human Monocytes

1986 • 106 citations

VASCULAR ENDOTHELIAL GROWTH FACTOR EXPRESSION IN TRANSPLANTED HUMAN HEARTS1,2

1995 • 63 citations

Mono-ADP-ribosylation: A Reversible Posttranslational Modification of Proteins

1996 • 58 citations

[21] In Vitro ADP-ribosylation of Rho by bacterial ADP-ribosyltransferases

1995 • 57 citations

Inhibitors and activators of ADP-ribosylation reactions

1994 • 56 citations

Lactate stimulation of macrophage-derived angiogenic activity is associated with inhibition of Poly(ADP-ribose) synthesis.

1996 • 49 citations

Inhibition of production of monocyte/macrophage-derived angiogenic activity by oxygen free-radical scavengers

1992 • 32 citations

Induction of Neovascularization and Nonlymphoid Mesenchymal Cell Proliferation by Macrophage Cell Lines

1985 • 29 citations

Macrophages secrete a heparin-binding inhibitor of endothelial cell growth

1991 • 23 citations