CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-κB activation

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

Signaling to NF-κB

2004 • 3,768 citations

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

2001 • 2,027 citations

Ubiquitin signalling in the NF-κB pathway

2005 • 1,137 citations

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

1998 • 1,070 citations

G-protein-coupled receptors and signaling networks: emerging paradigms

2001 • 1,005 citations

Essential function for the kinase TAK1 in innate and adaptive immune responses

2005 • 927 citations

IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain

1999 • 812 citations

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

2002 • 803 citations

Endothelin System: The Double-Edged Sword in Health and Disease

2001 • 730 citations

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

2005 • 705 citations

The genetic basis of mammalian neurulation

2003 • 681 citations

The TRAF6 Ubiquitin Ligase and TAK1 Kinase Mediate IKK Activation by BCL10 and MALT1 in T Lymphocytes

2004 • 674 citations

Signal Transduction by Cell Adhesion Receptors and the Cytoskeleton: Functions of Integrins, Cadherins, Selectins, and Immunoglobulin-Superfamily Members

2002 • 597 citations

Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

2001 • 551 citations

Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

2003 • 524 citations

Lysophosphatidic acid: G-protein signalling and cellular responses

1997 • 492 citations

Epidermal growth factor-induced nuclear factor κB activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells

2000 • 355 citations

CARMA1 is a critical lipid raft–associated regulator of TCR-induced NF-κB activation

2002 • 338 citations

Phosphorylation of the CARMA1 Linker Controls NF-κB Activation

2005 • 333 citations

CARD11 and CARD14 Are Novel Caspase Recruitment Domain (CARD)/Membrane-associated Guanylate Kinase (MAGUK) Family Members that Interact with BCL10 and Activate NF-κB

2001 • 328 citations

The MAGUK Family Protein CARD11 Is Essential for Lymphocyte Activation

2003 • 326 citations

Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes

2001 • 320 citations

Identifying the MAGUK Protein Carma-1 as a Central Regulator of Humoral Immune Responses and Atopy by Genome-Wide Mouse Mutagenesis

2003 • 293 citations

A requirement for CARMA1 in TCR-induced NF-κB activation

2002 • 288 citations

Phosphorylation of CARMA1 Plays a Critical Role in T Cell Receptor-Mediated NF-κB Activation

2005 • 282 citations

Requirement for CARMA1 in Antigen Receptor-Induced NF-κB Activation and Lymphocyte Proliferation

2003 • 253 citations

CD3/CD28 Costimulation-Induced NF-κB Activation Is Mediated by Recruitment of Protein Kinase C-θ, Bcl10, and IκB Kinase β to the Immunological Synapse through CARMA1

2003 • 216 citations

A Role for NF-κB Essential Modifier/IκB Kinase-γ (NEMO/IKKγ) Ubiquitination in the Activation of the IκB Kinase Complex by Tumor Necrosis Factor-α

2003 • 209 citations

CARD11 mediates factor-specific activation of NF-κB by the T cell receptor complex

2002 • 206 citations

Carma1, a CARD‐containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF‐κB activation¹

2001 • 195 citations

Bimp1, a MAGUK Family Member Linking Protein Kinase C Activation to Bcl10-mediated NF-κB Induction

2001 • 182 citations

CARMA3/Bcl10/MALT1-dependent NF-κB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells

2006 • 165 citations

Mice Lacking the CARD of CARMA1 Exhibit Defective B Lymphocyte Development and Impaired Proliferation of Their B and T Lymphocytes

2003 • 149 citations

Regulation of nuclear factor kappaB activation by G-protein-coupled receptors.

2001 • 143 citations

CARD10 Is a Novel Caspase Recruitment Domain/Membrane-associated Guanylate Kinase Family Member That Interacts with BCL10 and Activates NF-κB

2001 • 140 citations

Regulation of nuclear factor κB activation by G-protein-coupled receptors

2001 • 135 citations

Protein Kinase Cδ Mediates Lysophosphatidic Acid-induced NF-κB Activation and Interleukin-8 Secretion in Human Bronchial Epithelial Cells

2004 • 129 citations

Bcl10 and Malt1 control lysophosphatidic acid-induced NF-κB activation and cytokine production

2006 • 103 citations

Phosphorylation and ubiquitination of the IκB kinase complex by two distinct signaling pathways

2007 • 102 citations

Bcl10 plays a critical role in NF-κB activation induced by G protein-coupled receptors

2006 • 101 citations

The CARMA1-Bcl10 Signaling Complex Selectively Regulates JNK2 Kinase in the T Cell Receptor-Signaling Pathway

2006 • 89 citations

Tumor Necrosis Factor Receptor-Associated Factor 6 (TRAF6) Deficiency Results in Exencephaly and Is Required for Apoptosis within the Developing CNS

2000 • 86 citations

The Molecular Adapter Carma1 Controls Entry of IκB Kinase into the Central Immune Synapse

2004 • 85 citations

Lysophosphatidic Acid Activates NF-κB in Fibroblasts

1999 • 82 citations

Physical and Functional Interaction of CARMA1 and CARMA3 with Iκ Kinase γ-NFκB Essential Modulator

2004 • 69 citations