CARMA3/Bcl10/MALT1-dependent NF-κB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells

Chapter 4 Preparation of Isolated Rat Liver Cells

1976 • 5,335 citations

Liver fibrosis

2005 • 4,286 citations

Signaling to NF-κB

2004 • 3,768 citations

G Protein Pathways

2002 • 1,222 citations

Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma

2000 • 978 citations

The TRAF6 Ubiquitin Ligase and TAK1 Kinase Mediate IKK Activation by BCL10 and MALT1 in T Lymphocytes

2004 • 674 citations

Bcl10 Is Involved in t(1;14)(p22;q32) of MALT B Cell Lymphoma and Mutated in Multiple Tumor Types

1999 • 666 citations

Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

2001 • 551 citations

Redox Regulation of NF-κB Activation: Distinct Redox Regulation Between the Cytoplasm and the Nucleus

2005 • 548 citations

Pleiotropic AT1 Receptor Signaling Pathways Mediating Physiological and Pathogenic Actions of Angiotensin II

2005 • 528 citations

NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis

2003 • 525 citations

Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

2003 • 524 citations

Angiotensin II induces contraction and proliferation of human hepatic stellate cells

2000 • 489 citations

Bcl10 and MALT1, Independent Targets of Chromosomal Translocation in MALT Lymphoma, Cooperate in a Novel NF-κB Signaling Pathway

2001 • 409 citations

Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats

2001 • 373 citations

Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II

2003 • 340 citations

CARMA1 is a critical lipid raft–associated regulator of TCR-induced NF-κB activation

2002 • 338 citations

Phosphorylation of the CARMA1 Linker Controls NF-κB Activation

2005 • 333 citations

CARD11 and CARD14 Are Novel Caspase Recruitment Domain (CARD)/Membrane-associated Guanylate Kinase (MAGUK) Family Members that Interact with BCL10 and Activate NF-κB

2001 • 328 citations

Phosphorylation of CARMA1 Plays a Critical Role in T Cell Receptor-Mediated NF-κB Activation

2005 • 282 citations

Identification of Paracaspases and Metacaspases

2000 • 233 citations

CD3/CD28 Costimulation-Induced NF-κB Activation Is Mediated by Recruitment of Protein Kinase C-θ, Bcl10, and IκB Kinase β to the Immunological Synapse through CARMA1

2003 • 216 citations

CARD11 mediates factor-specific activation of NF-κB by the T cell receptor complex

2002 • 206 citations

Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis

2001 • 196 citations

Carma1, a CARD‐containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF‐κB activation¹

2001 • 195 citations

Angiotensin II as a pro-inflammatory mediator.

2002 • 186 citations

Up-regulation of components of the renin-angiotensin system in the bile duct–ligated rat liver

2002 • 186 citations

Bimp1, a MAGUK Family Member Linking Protein Kinase C Activation to Bcl10-mediated NF-κB Induction

2001 • 182 citations

Angiotensin II induces gene transcription through cell-type-dependent effects on the nuclear factor-kappaB (NF-kappaB) transcription factor.

2000 • 181 citations

Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells

2004 • 157 citations

Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis

2001 • 157 citations

Oxidative stress is a critical mediator of the angiotensin II signal in human neutrophils: involvement of mitogen-activated protein kinase, calcineurin, and the transcription factor NF-κB

2003 • 157 citations

Liver Fibrogenesis: A New Role for the Renin–Angiotensin System

2005 • 152 citations

Mice Lacking the CARD of CARMA1 Exhibit Defective B Lymphocyte Development and Impaired Proliferation of Their B and T Lymphocytes

2003 • 149 citations

CIPER, a Novel NF κB-activating Protein Containing a Caspase Recruitment Domain with Homology to Herpesvirus-2 Protein E10

1999 • 142 citations

CARD10 Is a Novel Caspase Recruitment Domain/Membrane-associated Guanylate Kinase Family Member That Interacts with BCL10 and Activates NF-κB

2001 • 140 citations

Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver

2003 • 138 citations

Angiotensin II Induces Tumor Necrosis Factor Biosynthesis in the Adult Mammalian Heart Through a Protein Kinase C–Dependent Pathway

2002 • 134 citations

MALT1/Paracaspase Is a Signaling Component Downstream of CARMA1 and Mediates T Cell Receptor-induced NF-κB Activation

2004 • 120 citations

mE10, a Novel Caspase Recruitment Domain-containing Proapoptotic Molecule

1999 • 120 citations

Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice

2005 • 111 citations

NF-κB signaling in lymphocytes: a new cast of characters

2003 • 105 citations

Angiotensin II Induces Nuclear Factor- κ B Activation in Cultured Neonatal Rat Cardiomyocytes Through Protein Kinase C Signaling Pathway

2000 • 105 citations

Equine Herpesvirus-2 E10 Gene Product, but Not Its Cellular Homologue, Activates NF-κB Transcription Factor and c-Jun N-terminal Kinase

1999 • 101 citations

Angiotensinogen gene activation by angiotensin II is mediated by the rel A (nuclear factor-kappaB p65) transcription factor: one mechanism for the renin angiotensin system positive feedback loop in hepatocytes.

1996 • 100 citations

The Molecular Adapter Carma1 Controls Entry of IκB Kinase into the Central Immune Synapse

2004 • 85 citations

AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl4

2003 • 73 citations

Angiotensin II Induces Nuclear Factor (NF)-κB1 Isoforms to Bind the Angiotensinogen Gene Acute-Phase Response Element: A Stimulus-Specific Pathway for NF-κB Activation

2000 • 71 citations

Physical and Functional Interaction of CARMA1 and CARMA3 with Iκ Kinase γ-NFκB Essential Modulator

2004 • 69 citations

Complex and dynamic redistribution of NF-κB signaling intermediates in response to T cell receptor stimulation

2004 • 59 citations

Control of ascorbic acid efflux in rat luteal cells: role of intracellular calcium and oxygen radicals

2003 • 29 citations

Independence of Angiotensin II-Induced MAP Kinase Activation from Angiotensin Type 1 Receptor Internalization in Clone 9 Hepatocytes

2002 • 26 citations