Back to search

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

Data up to Jan 2025

Published2002
Citations803
References27

Total Citations Per Year

Abstract

References (27)

p53, the Cellular Gatekeeper for Growth and Division

1997 • 7,621 citations

Proliferation, cell cycle and apoptosis in cancer

2001 • 3,236 citations

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1993 • 2,969 citations

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

1999 • 2,179 citations

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.

1994 • 2,141 citations

Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

2000 • 2,064 citations

p63, a p53 Homolog at 3q27–29, Encodes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities

1998 • 2,061 citations

Tumor spectrum analysis in p53-mutant mice

1994 • 2,034 citations

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

2000 • 979 citations

p73 is a human p53-related protein that can induce apoptosis

1997 • 951 citations

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

1999 • 914 citations

Episomal Vectors Rapidly and Stably Produce High-Titer Recombinant Retrovirus

1996 • 768 citations

Role for the p53 homologue p73 in E2F-1-induced apoptosis

2000 • 700 citations

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis.

1993 • 677 citations

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1997 • 648 citations

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

1999 • 584 citations

Interaction of c-Abl and p73α and their collaboration to induce apoptosis

1999 • 542 citations

A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain

2001 • 454 citations

Requirement for Atm in Ionizing Radiation-Induced Cell Death in the Developing Central Nervous System

1998 • 425 citations

p73 Function Is Inhibited by Tumor-Derived p53 Mutants in Mammalian Cells

1999 • 418 citations

PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family

2000 • 397 citations

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells.

1994 • 290 citations

Target Gene Specificity of E2F and Pocket Protein Family Members in Living Cells

2000 • 230 citations

Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system

2000 • 150 citations

Oncogenes Induce and Activate Endogenous p73 Protein

2001 • 141 citations

Ataxia Telangiectasia Mutated-Dependent Apoptosis after Genotoxic Stress in the Developing Nervous System Is Determined by Cellular Differentiation Status

2001 • 122 citations

Role of the newer p53 family proteins in malignancy.

2001 • 82 citations

Cited By (0)

No citing papers found in database

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage (2002) – Nature | Metascience Observatory Explorer