Basement membrane type IV collagen degradation: evidence for the involvement of a proteolytic cascade independent of metalloproteinases.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1980 • 1,991 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane.

1981 • 587 citations

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase.

1989 • 579 citations

Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.

1986 • 531 citations

The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type.

1986 • 466 citations

Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.

1979 • 452 citations

Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells.

1987 • 323 citations

Collagenases

1974 • 303 citations

Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin 1 in parallel with collagenase.

1985 • 220 citations

Ras oncogene mediated induction of a 92kDa metalloproteinase; strong correlation with the malignant phenotype

1988 • 209 citations

Tumor invasion and host extracellular matrix

1983 • 176 citations

Activation of human breast carcinoma collagenase through plasminogen activator

1980 • 160 citations

Effect of Natural Protease Inhibitors and a Chemoattractant on Tumor Cell Invasion In Vitro

1982 • 141 citations

Correlation of the production of plasminogen activator with tumor metastasis in B16 mouse melanoma cell lines.

1980 • 138 citations

Stability and mobility of the collagen structure

1979 • 104 citations

Thermal stability of the triple helix of type I procollagen and collagen. Precautions for minimizing ultraviolet damage to proteins during circular dichroism studies

1979 • 97 citations

Degradation of native type IV procollagen by human neutrophil elastase. Implications for leukocyte-mediated degradation of basement membranes

1987 • 79 citations

Tissue inhibitor of metalloproteinases (timp) regulates extracellular type i collagen degradation by chondrocytes and endothelial cells

1987 • 74 citations

Involvement of plasminogen activator production with tumor metastasis in a rat model.

1984 • 66 citations

Decrease in plasminogen activator correlates with synapse elimination during neonatal development of mouse skeletal muscle.

1989 • 58 citations

Degradation of muscle basement membrane zone by locally generated plasmin

1987 • 32 citations

Connective tissue degradation by invasive rat bladder carcinomas: action of nonspecific proteinases on collagenous matrices.

1986 • 23 citations

The role of plasminogen activators in metastasis

1983 • 19 citations

Use of Inhibitory (Anti-Catalytic) Antibodies to study extracellular Proteolysis

1989 • 15 citations

Simultaneous stimulation of urokinase and tissue‐type plasminogen activators by phorbol esters in human ovarian carcinoma cells

1989 • 9 citations