Collagenases

COLLAGENOLYTIC ACTIVITY IN AMPHIBIAN TISSUES: A TISSUE CULTURE ASSAY

1962 • 1,275 citations

The interaction of α2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

1973 • 1,062 citations

The Chemistry and Structure of Collagen

1971 • 555 citations

Collagen Polymorphism: Characterization of Molecules with the Chain Composition [α1(III)] ₃ in Human Tissues

1974 • 524 citations

Tadpole Collagenase. Preparation and Purification^*

1966 • 390 citations

Cross-Linking of Collagen

1973 • 384 citations

The Neutral Proteases of Human Granulocytes

1973 • 366 citations

STUDIES ON HUMAN PLASMA α2-MACROGLOBULIN-ENZYME INTERACTIONS

1973 • 362 citations

Specific degradation of the collagen molecule by tadpole collagenolytic enzyme.

1965 • 339 citations

Human Granulocyte Collagenase

1968 • 335 citations

CHICK CARTILAGE COLLAGEN: A NEW TYPE OF α1 CHAIN NOT PRESENT IN BONE OR SKIN OF THE SPECIES

1969 • 329 citations

Degradation of collagen by a human granulocyte collagenolytic system

1968 • 298 citations

Synthesis of (Pro-Hyp-Gly)n of defined molecular weights Evidence for the stabilization of collagen triple helix by hydroxypyroline

1973 • 291 citations

Collagenolytic activity during mammalian wound repair

1967 • 261 citations

Action of Proteolytic Enzymes on Tropocollagen and Insoluble Collagen^*

1966 • 258 citations

An endopeptidase from rheumatoid synovial tissue culture

1972 • 252 citations

Some Properties of the Products of Reaction of Tadpole Collagenase with Collagen^*

1967 • 246 citations

The Nature of the Collagen Synthesized by Cultured Human Fibroblasts

1971 • 238 citations

The release of collagenase as an inactive proenzyme by bone explants in culture

1972 • 236 citations

The Biosynthesis of Collagen

1972 • 235 citations

Hydroxyproline content determines the denaturation temperature of chick tendon collagen

1973 • 224 citations

Collagenases in human synovial fluid

1969 • 215 citations

Human Collagenase: Identification and Characterization of an Enzyme from Rheumatoid Synovium in Culture

1967 • 197 citations

Zymogen of tadpole collagenase

1971 • 194 citations

Evidence for Procollagen, a Biosynthetic Precursor of Collagen

1971 • 193 citations

Isolation of two distinct collagens from chick cartilage

1970 • 193 citations

Effects of colchicine on collagenase in cultures of rheumatoid synovium

1971 • 189 citations

Catabolism of collagen and non-collagen protein in the rat uterus during post-partum involution

1962 • 179 citations

Studies on the Structure of Collagen Utilizing a Collagenolytic Enzyme from Tadpole^*

1966 • 169 citations

A specific collagenase from rabbit fibroblasts in monolayer culture

1974 • 168 citations

Zymogens of Proteolytic Enzymes

1973 • 168 citations

Properties of a collagen molecule containing three identical components extracted from bovine articular cartilage

1971 • 154 citations

Further evidence for a transport form of collagen. Its extrusion and extracellular conversion to tropocollagen in embryonic tendon

1971 • 135 citations

The role of epithelium and mesenchyme in the production of a collagenolytic enzyme and a hyaluronidase in the anuran tadpole

1965 • 130 citations

A New Particle Type in Certain Connective Tissue Extracts

1953 • 127 citations

Collagenase from rat uterus. Isolation and partial characterization

1970 • 123 citations

Animal and Human Collagenases**From the Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110.

1970 • 123 citations

The Origin of Collagenase in Periodontal Tissues of Man

1969 • 121 citations

Mammalian collagenase: Direct demonstration in homogenates of involuting rat uterus

1971 • 118 citations

Phagocytic Release and Activation of Human Leukocyte Procollagenase

1973 • 115 citations

Human Skin Collagenase: Localization and Distribution in Normal Human Skin

1969 • 112 citations

Human Skin Collagenase. The Role of Serum Alpha-Globulins in the Control of Activity In Vivo and In Vitro

1971 • 107 citations

Band pattern of the segment-long-spacing form of collagen. Its use in the analysis of primary structure

1973 • 106 citations

The time‐course and route of loss of collagen from the rat's uterus during post‐partum involution

1956 • 103 citations

The Limited Cleavage of Native Collagen with Chymotrypsin, Trypsin, and Cyanogen Bromide^*

1966 • 102 citations

A Transport Form of Collagen from Embryonic Tendon: Electron Microscopic Demonstration of an NH ₂ -Terminal Extension and Evidence Suggesting the Presence of Cystine in the Molecule

1972 • 98 citations

Isolation and characterization of collagenases I and II from Clostridium histolyticum

1965 • 95 citations

Preparation and properties of collagenases from epithelium and mesenchyme of healing mammalian wounds

1971 • 95 citations

Activation of leucocyte collagenase proenzyme by rheumatoid synovial fluid

1972 • 93 citations

Collagenase and rheumatoid arthritis

1970 • 89 citations

Evidence for the Presence of a Complex of Collagenase with α2-Macroglobulin in Human Rheumatoid Synovial Fluid

1973 • 77 citations

Empire Rheumatism Council : Multi-Centre Controlled Trial of Cortisone Acetate and Acetyl Salicylic Acid in the Long-Term Treatment of Rheumatoid Arthritis Results of Three Years' Treatment

1957 • 71 citations

Collagenase, procollagenase and activator relationships in tadpole tissue cultures

1972 • 70 citations

Mouse bone collagenase

1973 • 69 citations

Further Studies on a Collagenase in Middle Ear Cholesteatoma

1971 • 66 citations

Vertebrate collagenase: Further characterization and the significance of its latent form in vivo

1973 • 63 citations

The presence of collagenase in Kupffer cells of the rat liver

1973 • 59 citations

Multiple steps in the activation of the inactive precursor of bone collagenase by trypsin

1972 • 57 citations

Collagenase in carcinoma cells

1972 • 56 citations

[44] Collagenases

1970 • 54 citations

A collagenolytic system produced by primary cultures of rheumatoid nodule tissue

1972 • 53 citations

Regulation of Vertebrate Collagenase Activity In Vivo and In Vitro

1972 • 48 citations

Studies on purified rheumatoid synovial collagenase in vitro and in vivo

1971 • 48 citations

The Internal Remodeling of Bones

1971 • 46 citations

Collagenase activity in homogenates of the involuting rat uterus

1973 • 38 citations

Synovial Collagenase and Joint Diseases: The Significancy of Latent Collagenase with Special Reference to Rheumatoid Arthritis

1973 • 38 citations

Vertebrate Collagenase: Direct Extraction from Animal Skin and Human Synovial Membrane

1972 • 33 citations

Electron microscope studies on collagen

1964 • 32 citations

Further studies on the nature of the components in serum which inhibit mouse bone collagenase

1972 • 29 citations

Isolation of tissue collagenase from homogenates of embryonic chick bones

1973 • 27 citations

Molecular Fragments of Rat Skin Collagen Obtained on Collagenase Digestion

1968 • 27 citations

Further characterization of procollagen: The identification of a pro-α2 chain

1972 • 27 citations

Specificity of bacterial collagenase: Studies with peptides newly synthesized using the solid-phase method

1972 • 26 citations

Sixth Annual Herman Beerman Lecture

1966 • 22 citations

Evidence for the Role of Collagenase in Collagen Metabolism

1971 • 20 citations

Maintenance of Mouse Bone Collagenase Activity in the Presence of Serum Protein by Addition of Trypsin

1972 • 19 citations

Collagenase and Hyaluronidase Stimulation by Dibutyryl Adenosine Cyclic 3′:5′-Monophosphate

1973 • 19 citations

Homeostasis in Extracellular Tissues: Insights from Studies on Collage

1973 • 17 citations

Dynamic aspects of collagen biology. Part II: Degradation and metabolism

1967 • 14 citations

Collagenase and Periodontal Diseases: A Review

1971 • 12 citations