Lineage-specific expression of a T cell receptor variable gene promoter controlled by upstream sequences.

Identification of common molecular subsequences

1981 • 9,753 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Somatic generation of antibody diversity

1983 • 3,275 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.

1983 • 861 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 772 citations

Ordered rearrangement of immunoglobulin heavy chain variable region segments.

1984 • 736 citations

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

1985 • 710 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

1985 • 588 citations

Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes

1981 • 497 citations

Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.

1983 • 457 citations

Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase

1986 • 452 citations

A lymphocyte-specific enhancer in the mouse immunoglobulin κ gene

1984 • 410 citations

Regulation of the Assembly and Expression of Variable-Region Genes

1986 • 402 citations

The human β-interferon gene enhancer is under negative control

1986 • 395 citations

Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes

1981 • 327 citations

Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence

1985 • 313 citations

Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter.

1988 • 308 citations

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

1986 • 308 citations

Regulation of human interleukin-2 gene: Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes

1986 • 288 citations

A novel transcription property of SP6 and T7 RNA polymerases: dependence on template structure

1985 • 267 citations

Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells

1984 • 261 citations

Functional relationships between transcriptional control signals of the thymidine kinase gene of herpes simplex virus

1982 • 253 citations

Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H–2 gene

1986 • 252 citations

Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA

1983 • 232 citations

The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum

1983 • 217 citations

Conserved major histocompatibility complex class II boxes--X and Y--are transcriptional control elements and specifically bind nuclear proteins.

1987 • 212 citations

Two regulatory elements for immunoglobulin kappa light chain gene expression.

1984 • 197 citations

A 3′ enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult β-globin gene

1986 • 192 citations

Transcription of T cell receptor beta-chain genes is controlled by a downstream regulatory element.

1988 • 185 citations

CAT vectors for analysis of eukaryotic promoters and enhancers

1986 • 184 citations

Regulation of growth hormone messenger RNA synthesis by dexamethasone and triiodothyronine

1985 • 173 citations

Immunoglobulin Gene Rearrangement in Immature B Cells

1980 • 172 citations

Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells.

1986 • 171 citations

Expression of the immunoglobulin C mu gene in mouse T and B lymphoid and myeloid cell lines.

1980 • 170 citations

Transcription of mouse kappa chain genes: implications for allelic exclusion.

1980 • 167 citations

Fusion of an immunoglobulin variable gene and a T cell receptor constant gene in the chromosome 14 inversion associated with T cell tumors

1985 • 166 citations

Identification of the Receptor for Antigen and Major Histocompatibility Complex on Human Inducer T Lymphocytes

1983 • 165 citations

Cell type-specific enhancer element associated with a mouse MHC gene, Eβ

1984 • 162 citations

Chromatin changes accompany immunoglobulin κ gene activation: a potential control region within the gene

1982 • 138 citations

A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci

1986 • 136 citations

Regulation of Gene Expression by Interferons: Control of H-2 Promoter Responses

1988 • 136 citations

Genes encoding the Ti β subunit of the antigen/MHC receptor undergo rearrangement during intrathymic ontogeny prior to surface T3-Ti expression

1984 • 134 citations

Reversible silencing of enhancers by sequences derived from the human IFN-α promoter

1987 • 119 citations

A Transcriptional Enhancer 3′ of C _β2 in the T Cell Receptor β Locus

1988 • 118 citations

High expression of cloned immunoglobulin k gene in transgenic mice is restricted to B lymphocytes

1984 • 114 citations

Simple DNA sequences in homologous flanking regions near immunoglobulin V_Hgenes: a role in gene interaction?

1982 • 99 citations

A Murine T Cell Receptor Gene Complex: Isolation, Structure and Rearrangement

1984 • 89 citations

Site-specific recombination between immunoglobulin D and JH segments that were introduced into the genome of a murine pre-B cell line

1984 • 77 citations

A conserved sequence in the T-cell receptor beta-chain promoter region.

1988 • 74 citations

The mechanism of chromosome 14 inversion in a human T cell lymphoma

1987 • 70 citations

Erythroid-specific transcription of the chicken histone H5 gene is directed by a 3′ enhancer

1987 • 70 citations

Promoter Region of Interleukin-2 Gene Undergoes Chromatin Structure Changes and Confers Inducibility on Chloramphenicol Acetyltransferase Gene During Activation of T Cells

1986 • 67 citations

Identification of negative and positive regulatory elements associated with a class I major histocompatibility complex gene.

1988 • 65 citations

Analysis of a human V beta gene subfamily.

1986 • 63 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 54 citations

Localization of a repressive sequence contributing to B-cell specificity in the immunoglobulin heavy-chain enhancer.

1988 • 53 citations

A Transcriptional Enhancer and an Interferon-Responsive Sequence in Major Histocompatibility Complex Class I Genes

1986 • 52 citations

Promoter and enhancer elements in the rearranged alpha chain gene of the human T cell receptor.

1987 • 50 citations

Functional isotypes are not encoded by the constant region genes of the beta subunit of the T cell receptor for antigen/major histocompatibility complex.

1984 • 49 citations

Regulation of the Assembly and Expression of Variable-Region Genes

1986 • 32 citations

Multiple nuclear proteins bind upstream sequences in the promotor region of a T-cell receptor beta-chain variable-region gene: evidence for tissue specificity.

1987 • 31 citations

Localization of a Repressive Sequence Contributing to B-Cell Specificity in the Immunoglobulin Heavy-Chain Enhancer

1988 • 22 citations