Conserved major histocompatibility complex class II boxes--X and Y--are transcriptional control elements and specifically bind nuclear proteins.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

ROLE OF ABERRANT HLA-DR EXPRESSION AND ANTIGEN PRESENTATION IN INDUCTION OF ENDOCRINE AUTOIMMUNITY

1983 • 1,275 citations

Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.

1985 • 1,052 citations

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

1985 • 763 citations

Transcriptional selectivity of viral genes in mammalian cells

1986 • 722 citations

Fine Structure Genetic Analysis of a β-Globin Promoter

1986 • 479 citations

Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter

1986 • 336 citations

Diversity of Alpha-Fetoprotein Gene Expression in Mice Is Generated by a Combination of Separate Enhancer Elements

1987 • 315 citations

Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes.

1983 • 245 citations

Heat shock regulatory elements function as an inducible enhancer in the xenopus hsp70 gene and when linked to a heterologous promoter

1986 • 239 citations

G to A substitution in the distal CCAAT box of the Aγ-globin gene in Greek hereditary persistence of fetal haemoglobin

1985 • 198 citations

A point mutation in the Aγ-globin gene promoter in Greek hereditary persistence of fetal haemoglobin

1985 • 189 citations

The murine Eα immune response gene

1983 • 180 citations

Correcting an immune-response deficiency by creating Eα gene transgenic mice

1985 • 171 citations

A Genetic Approach to Promoter Recognition During trans Induction of Viral Gene Expression

1986 • 163 citations

Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex.

1983 • 161 citations

Complete nucleotide sequence of a functional HLA-DPβ gene and the region between the DPβ1 and DPα1 genes: comparison of the 5′ ends of HLA class II genes

1985 • 132 citations

Oligonucleotide-directed mutagenesis by microscale ‘shot-gun’ gene synthesis

1985 • 105 citations

Molecular Genetics of the Human Major Histocompatibility Complex

1986 • 78 citations

Inbred and wild mice carry identical deletions in their E alpha MHC genes.

1985 • 51 citations

Organization and Expression of the MHC of the C57 Black/10 Mouse

1985 • 47 citations

Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes.

1986 • 46 citations

Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat.

1985 • 24 citations

Alternate Utilization of Two Regulatory Domains Within the Moloney Murine Sarcoma Virus Long Terminal Repeat

1985 • 9 citations