Role of Region C in Regulation of the Heat Shock Gene-Specific Sigma Factor of Escherichia coli , ς ³²

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter

1995 • 4,806 citations

Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK

1996 • 1,247 citations

Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries

1997 • 797 citations

[6] Efficient site-directed mutagenesis using uracil-containing DNA

1991 • 644 citations

Is hsp70 the cellular thermometer?

1991 • 586 citations

Production of abnormal proteins in E. coli stimulates transcription of ion and other heat shock genes

1985 • 521 citations

REGULATION OF THE HEAT-SHOCK RESPONSE IN BACTERIA

1993 • 473 citations

Escherichia coli FtsH is a membrane-bound, ATP-dependent protease which degrades the heat-shock transcription factor sigma 32.

1995 • 430 citations

The heat shock response of E. coli is regulated by changes in the concentration of σ32

1987 • 414 citations

Interaction of Hsp70 chaperones with substrates

1997 • 372 citations

DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32.

1990 • 356 citations

Regulation of the Escherichia coli heat‐shock response

1993 • 338 citations

The dnaK protein modulates the heat-shock response of Escherichia coli

1983 • 328 citations

Purification and properties of the .sigma. subunit of Escherichia coli DNA-dependent RNA polymerase

1979 • 319 citations

Physical interaction between heat shock proteins DnaK, DnaJ, and GrpE and the bacterial heat shock transcription factor σ32

1992 • 314 citations

Degradation of sigma 32, the heat shock regulator in Escherichia coli, is governed by HflB.

1995 • 308 citations

A cycle of binding and release of the DnaK, DnaJ and GrpE chaperones regulates activity of the Escherichia coli heat shock transcription factor sigma32.

1996 • 281 citations

Crystal Structure of a σ70 Subunit Fragment from E. coli RNA Polymerase

1996 • 278 citations

Degradation of carboxy-terminal-tagged cytoplasmic proteins by the Escherichia coli protease HflB (FtsH)

1998 • 268 citations

Regulation of theXmyf-5andXmyoDExpression Pattern during Early Xenopus Development

1998 • 211 citations

Levels of DnaK and DnaJ provide tight control of heat shock gene expression and protein repair in Escherichia coli

1998 • 196 citations

The DnaK chaperone modulates the heat shock response of Escherichia coli by binding to the sigma 32 transcription factor.

1992 • 178 citations

The DnaK Chaperone System of Escherichia coli: Quaternary Structures and Interactions of the DnaK and GrpE Components

1995 • 169 citations

Characterization of the Escherichia coli transcription factor .sigma.70: localization of a region involved in the interaction with core RNA polymerase

1989 • 144 citations

Domain Organization of the RNA Polymerase σ70Subunit

1996 • 137 citations

The chaperone function of DnaK requires the coupling of ATPase activity with substrate binding through residue E171.

1994 • 118 citations

Heat shock regulation in the ftsH null mutant of Escherichia coli: dissection of stability and activity control mechanisms of σ³²in vivo

1998 • 117 citations

Autoregulation of the Escherichia coli heat shock response by the DnaK and DnaJ heat shock proteins.

1993 • 116 citations

Regulatory Region C of theE. coliHeat Shock Transcription Factor, σ32, Constitutes a DnaK Binding Site and is Conserved Among Eubacteria

1996 • 113 citations

The activity of sigma 32 is reduced under conditions of excess heat shock protein production in Escherichia coli.

1989 • 109 citations

Molecular Chaperones and Folding Catalysts: Regulation, Cellular Functions and Mechanisms

1999 • 102 citations

Isolation and sequence analysis of rpoH genes encoding sigma 32 homologs from gram negative bacteria: conserved mRNA and protein segments for heat shock regulation.

1995 • 100 citations

Kinetic Characterization of the ATPase Cycle of the DnaK Molecular Chaperone

1998 • 93 citations

The DnaJ chaperone catalytically activates the DnaK chaperone to preferentially bind the sigma 32 heat shock transcriptional regulator.

1995 • 91 citations

On the mechanism of FtsH‐dependent degradation of the σ³² transcriptional regulator of Escherichia coli and the role of the DnaK chaperone machine

1999 • 86 citations

Induction of heat shock proteins by abnormal proteins results from stabilization and not increased synthesis of sigma 32 in Escherichia coli

1994 • 81 citations

Both ambient temperature and the DnaK chaperone machine modulate the heat shock response in Escherichia coli by regulating the switch between sigma 70 and sigma 32 factors assembled with RNA polymerase.

1995 • 68 citations

A distinct segment of the sigma 32 polypeptide is involved in DnaK-mediated negative control of the heat shock response in Escherichia coli.

1994 • 65 citations

A mutant sigma 32 with a small deletion in conserved region 3 of sigma has reduced affinity for core RNA polymerase

1992 • 59 citations

A mutation that enhances synthesis of sigma 32 and suppresses temperature-sensitive growth of the rpoH15 mutant of Escherichia coli

1990 • 55 citations

Multiple Regions on the Escherichia coli Heat Shock Transcription Factor ς ³² Determine Core RNA Polymerase Binding Specificity

1998 • 51 citations

Regions of the Escherichia coli primary sigma factor σ⁷⁰ that are involved in interaction with RNA polymerase core enzyme

1997 • 48 citations

Molecular chaperones and folding catalysts : regulation, cellular function and mechanisms

1999 • 42 citations

GENETIC EVIDENCE FOR THE ROLES OF MOLECULAR CHAPERONES IN ESCHERICHIA COLI METABOLISM

1999 • 1 citations