Induction of heat shock proteins by abnormal proteins results from stabilization and not increased synthesis of sigma 32 in Escherichia coli

MOLECULAR CHAPERONE FUNCTIONS OF HEAT-SHOCK PROTEINS

1993 • 1,591 citations

Role of the Major Heat Shock Proteins as Molecular Chaperones

1993 • 1,096 citations

Abnormal Proteins Serve as Eukaryotic Stress Signals and Trigger the Activation of Heat Shock Genes

1986 • 904 citations

The htpR gene product of E. coli is a sigma factor for heat-shock promoters

1984 • 593 citations

Is hsp70 the cellular thermometer?

1991 • 586 citations

The effect of amino acid analogues and heat shock on gene expression in chicken embryo fibroblasts

1978 • 547 citations

Production of abnormal proteins in E. coli stimulates transcription of ion and other heat shock genes

1985 • 521 citations

REGULATION OF THE HEAT-SHOCK RESPONSE IN BACTERIA

1993 • 473 citations

The heat shock response of E. coli is regulated by changes in the concentration of σ32

1987 • 414 citations

DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32.

1990 • 356 citations

Regulation of the Escherichia coli heat‐shock response

1993 • 338 citations

The dnaK protein modulates the heat-shock response of Escherichia coli

1983 • 328 citations

Genetic control of heat-shock protein synthesis and its bearing on growth and thermal resistance in Escherichia coli K-12.

1982 • 322 citations

Physical interaction between heat shock proteins DnaK, DnaJ, and GrpE and the bacterial heat shock transcription factor σ32

1992 • 314 citations

Sigma 32 synthesis can regulate the synthesis of heat shock proteins in Escherichia coli.

1987 • 249 citations

Isolation and characterization of Escherichia coli mutants that lack the heat shock sigma factor sigma 32

1988 • 219 citations

Escherichia coli heat shock gene mutants are defective in proteolysis.

1988 • 205 citations

Induction of a heat shock-like response by unfolded protein in Escherichia coli: dependence on protein level not protein degradation.

1989 • 180 citations

The DnaK chaperone modulates the heat shock response of Escherichia coli by binding to the sigma 32 transcription factor.

1992 • 178 citations

Heat shock protein GroE of Escherichia coli: key protective roles against thermal stress.

1988 • 171 citations

Modulation of stability of the Escherichia coli heat shock regulatory factor sigma

1989 • 169 citations

Toxic Amino Acids: Their Action as Antimetabolites

1967 • 160 citations

Interplay of two cis-acting mRNA regions in translational control of sigma 32 synthesis during the heat shock response of Escherichia coli.

1991 • 154 citations

Temperature-induced synthesis of specific proteins in Escherichia coli: evidence for transcriptional control

1980 • 129 citations

Autoregulation of the Escherichia coli heat shock response by the DnaK and DnaJ heat shock proteins.

1993 • 116 citations

8 The Function and Regulation of Heat Shock Proteins in Escherichia coli

1990 • 103 citations

Accumulation of secretory protein precursors in Escherichia coli induces the heat shock response

1993 • 83 citations

9 Properties of the Escherichia coli Heat Shock Proteins and Their Role in Bacteriophage λ Growth

1990 • 76 citations

Induction of the heat shock response of E. coli through stabilization of sigma 32 by the phage lambda cIII protein.

1987 • 76 citations

Isolation and physical mapping of temperature-sensitive mutants defective in heat-shock induction of proteins in Escherichia coli

1984 • 71 citations

Heat induction of θ³²synthesis mediated by mRNA secondary structure: a primary step of the heat shock response inEscherichia coli

1993 • 69 citations

A distinct segment of the sigma 32 polypeptide is involved in DnaK-mediated negative control of the heat shock response in Escherichia coli.

1994 • 65 citations

Translational regulation of sigma 32 synthesis: requirement for an internal control element

1991 • 62 citations

A mutation that enhances synthesis of sigma 32 and suppresses temperature-sensitive growth of the rpoH15 mutant of Escherichia coli

1990 • 55 citations

Divergent effects of a dnaK mutation on abnormal protein degradation in Escherichia coli

1988 • 55 citations

Diverse effects of the MalE-LacZ hybrid protein on Escherichia coli cell physiology

1986 • 48 citations

Response of Escherichia coli cell membranes to induction of ? c1857 prophage by heat shock

1991 • 43 citations