The DnaK chaperone modulates the heat shock response of Escherichia coli by binding to the sigma 32 transcription factor.

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2013 • 47,043 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

Escherichia Coli and Salmonella: Typhimurium Cellular and Molecular Biology

1987 • 4,385 citations

Escherichia coli and Salmonella typhimurium: Cellular and molecular biology

1988 • 3,957 citations

Procedure for the rapid, large-scale purification of Escherichia coli DNA-dependent RNA polymerase involving polymin P precipitation and DNA-cellulose chromatography

1975 • 1,157 citations

Proteins as molecular chaperones

1987 • 910 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK.

1991 • 835 citations

The htpR gene product of E. coli is a sigma factor for heat-shock promoters

1984 • 593 citations

Is hsp70 the cellular thermometer?

1991 • 586 citations

Stress proteins in biology and medicine

1990 • 502 citations

Identification of the sigma E subunit of Escherichia coli RNA polymerase: a second alternate sigma factor involved in high-temperature gene expression.

1989 • 422 citations

The heat shock response of E. coli is regulated by changes in the concentration of σ32

1987 • 414 citations

The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner

1990 • 407 citations

Consensus sequence for Escherichia coli heat shock gene promoters.

1985 • 372 citations

DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32.

1990 • 356 citations

Multicopy expression vectors carrying the lac represser gene for regulated high-level expression of genes in Escherichia coli

1987 • 339 citations

The dnaK protein modulates the heat-shock response of Escherichia coli

1983 • 328 citations

A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein.

1989 • 296 citations

Initiation of lambda DNA replication with purified host- and bacteriophage-encoded proteins: the role of the dnaK, dnaJ and grpE heat shock proteins.

1989 • 294 citations

Characterization of YDJ1: a yeast homologue of the bacterial dnaJ protein.

1991 • 284 citations

The dnaK protein of Escherichia coli possesses an ATPase and autophosphorylating activity and is essential in an in vitro DNA replication system.

1983 • 260 citations

The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein

1991 • 245 citations

A quantitative assay for bacterial RNA polymerases.

1979 • 216 citations

Escherichia coli heat shock gene mutants are defective in proteolysis.

1988 • 205 citations

Characterization of SIS1, a Saccharomyces cerevisiae homologue of bacterial dnaJ proteins.

1991 • 198 citations

Regulation of the promoters and transcripts of rpoH, the Escherichia coli heat shock regulatory gene.

1987 • 191 citations

Monomerization of RepA dimers by heat shock proteins activates binding to DNA replication origin.

1991 • 183 citations

Heat-shock proteins DnaK and GroEL facilitate export of LacZ hybrid proteins in E. coli

1990 • 175 citations

Modulation of stability of the Escherichia coli heat shock regulatory factor sigma

1989 • 169 citations

Heat Shock Protein-mediated Disassembly of Nucleoprotein Structures Is Required for the Initiation of Bacteriophage λ DNA Replication

1989 • 165 citations

The grpE protein of Escherichia coli. Purification and properties.

1987 • 160 citations

Molecular cloning and expression of a gene that controls the high-temperature regulon of Escherichia coli

1983 • 128 citations

Aggregated dnaA protein is dissociated and activated for DNA replication by phospholipase or dnaK protein.

1990 • 119 citations

A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast

1991 • 117 citations

The activity of sigma 32 is reduced under conditions of excess heat shock protein production in Escherichia coli.

1989 • 109 citations

Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP.

1988 • 106 citations

Isolation and characterization of dnaJ null mutants of Escherichia coli

1990 • 103 citations

Three Escherichia coli heat shock proteins are required for P1 plasmid DNA replication: formation of an active complex between E. coli DnaJ protein and the P1 initiator protein.

1990 • 100 citations

Reconstitution of a nine-protein system that initiates bacteriophage λ DNA replication

1989 • 98 citations

Transcriptional regulation of the heat shock regulatory gene rpoH in Escherichia coli: involvement of a novel catabolite-sensitive promoter

1990 • 82 citations

dnaA protein regulates transcriptions of the rpoH gene of Escherichia coli

1989 • 79 citations

Physical interactions between bacteriophage and Escherichia coli proteins required for initiation of lambda DNA replication.

1990 • 75 citations

Translational regulation of sigma 32 synthesis: requirement for an internal control element

1991 • 62 citations

DNA supercoiling and temperature shift affect the promoter activity of the Escherichia coli rpoH gene encoding the heat-shock sigma subunit of RNA polymerase

1989 • 61 citations

Interaction between heat shock protein DnaK and recombinant staphylococcal protein A

1990 • 42 citations

Correlation between the 32-kDa sigma factor levels and in vitro expression of Escherichia coli heat shock genes.

1987 • 33 citations

Purification of Complexes of Nuclear Oncogene p53 with Rat and Escherichia coli Heat Shock Proteins: In Vitro Dissociation of hsc70 and dnaK from Murine p53 by ATP

1988 • 28 citations

Antibody to sigma 32 cross-reacts with DnaK: association of DnaK protein with Escherichia coli RNA polymerase.

1988 • 23 citations

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