The coactivators p300 and CBP have different functions during the differentiation of F9 cells

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

A decade of molecular biology of retinoic acid receptors

1996 • 2,893 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Histone acetylation in chromatin structure and transcription

1997 • 2,834 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

1993 • 1,902 citations

Histone acetylation and transcriptional regulatory mechanisms

1998 • 1,793 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway

1995 • 1,453 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1).

1978 • 1,303 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

1995 • 1,197 citations

DNA damage activates p53 through a phosphorylation–acetylation cascade

1998 • 1,194 citations

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

1993 • 1,047 citations

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

1994 • 1,046 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

Gene Dosage–Dependent Embryonic Development and Proliferation Defects in Mice Lacking the Transcriptional Integrator p300

1998 • 984 citations

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

1992 • 906 citations

What's Up and Down with Histone Deacetylation and Transcription?

1997 • 831 citations

Physical interaction of the retinoblastoma protein with human D cyclins

1993 • 780 citations

Binding and modulation of p53 by p300/CBP coactivators

1997 • 698 citations

Recruitment of p300/CBP in p53-Dependent Signal Pathways

1997 • 671 citations

Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions

1998 • 639 citations

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.

1995 • 603 citations

Synergistic activation of transcription by CBP and p53

1997 • 599 citations

Acetylation of general transcription factors by histone acetyltransferases

1997 • 588 citations

c-Jun is essential for normal mouse development and hepatogenesis

1993 • 543 citations

A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

1995 • 534 citations

ATF-2 contains a phosphorylation-dependent transcriptional activation domain.

1995 • 504 citations

Characterization of junD: a new member of the jun proto-oncogene family.

1989 • 492 citations

The p300/CBP family: integrating signals with transcription factors and chromatin

1997 • 482 citations

Differential Roles of p300 and PCAF Acetyltransferases in Muscle Differentiation

1997 • 419 citations

p300/MDM2 Complexes Participate in MDM2-Mediated p53 Degradation

1998 • 415 citations

Conjunction dysfunction: CBP/p300 in human disease

1998 • 406 citations

Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.

1989 • 396 citations

A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture.

1993 • 393 citations

A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein

1990 • 391 citations

Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein.

1993 • 380 citations

Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases

1998 • 345 citations

Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation

1998 • 330 citations

Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro.

1995 • 318 citations

Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A

1998 • 298 citations

Abnormal skeletal patterning in embryos lacking a single Cbp allele: A partial similarity with Rubinstein–Taybi syndrome

1997 • 289 citations

Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signalling

1997 • 283 citations

Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice

1996 • 268 citations

Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains

1994 • 256 citations

Association of p300 and CBP with Simian Virus 40 Large T Antigen

1996 • 246 citations

Linking histone acetylation to transcriptional regulation

1998 • 222 citations

Differential Use of CREB Binding Protein-Coactivator Complexes

1998 • 218 citations

The multifunctional role of the co-activator CBP in transcriptional regulation.

1997 • 197 citations

CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein.

1997 • 183 citations

A CBP/p300 homolog specifies multiple differentiation pathways in Caenorhabditis elegans

1998 • 176 citations

Tissue-specific expression of c-jun and junB during organogenesis in the mouse

1989 • 172 citations

CREB-binding Protein Activates Transcription through Multiple Domains

1996 • 170 citations

Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300/CBP-interacting regionSelfcloseTable

1997 • 169 citations

Mouse teratocarcinoma cells: Prospects for the study of embryogenesis and neoplasia

1981 • 152 citations

The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300.

1996 • 147 citations

p300, and p300-associated proteins, are components of TATA-binding protein (TBP) complexes.

1993 • 120 citations

Differential Transcriptional Activation by Human T-Cell Leukemia Virus Type 1 Tax Mutants Is Mediated by Distinct Interactions with CREB Binding Protein and p300

1998 • 119 citations

Drosophila CBP is required for dorsal–dependent twist gene expression

1997 • 118 citations

Ectopic expression of c-jun leads to differentiation of P19 embryonal carcinoma cells.

1990 • 111 citations

E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products.

1991 • 102 citations

Functional interactions within adenovirus E1A protein complexes.

1994 • 100 citations

Transcriptional Activation by the Adenovirus Larger E1a Product is Mediated by Members of the Cellular Transcription Factor ATF Family Which Can Directly Associate with E1a

1993 • 99 citations

Adenovirus E1A negatively and positively modulates transcription of AP-1 dependent genes by dimer-specific regulation of the DNA binding and transactivation activities of Jun.

1993 • 98 citations

Phosphorylation of the adenovirus E1A-associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cells.

1995 • 94 citations

p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells

1998 • 91 citations

Differential Effects of the Adenovirus E1A Oncogene on Members of the AP-1 Transcription Factor Family

1990 • 83 citations

Construction of a 1.2-Mb Contig Surrounding, and Molecular Analysis of, the Human CREB-Binding Protein (CBP/CREBBP) Gene on Chromosome 16p13.3

1997 • 83 citations

Differential regulation of three members of the ATF/CREB family of DNA-binding proteins.

1991 • 82 citations

Elevation of AP1 activity during F9 cell differentiation is due to increased c-jun transcription.

1990 • 82 citations

Transcriptional regulation of the c-jun gene by retinoic acid and E1A during differentiation of F9 cells.

1992 • 81 citations

The adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2

1993 • 80 citations

Retinoic acid, dibutyryl-cAMP, and differentiation affect the expression of retinoic acid receptors in F9 cells.

1990 • 78 citations

Differentiation of F9 embryonal carcinoma cells induced by the c-jun and activated c-Ha-ras oncogenes.

1990 • 69 citations

Differential expression ofjunandfosgenes during differentiation of mouse P19 embryonal carcinoma cells

1990 • 65 citations

Apoptosis during Retinoic Acid-Induced Differentiation of F9 Embryonal Carcinoma Cells

1994 • 62 citations

Transcriptional control of c-junby retinoic acid

1991 • 54 citations

Positive regulation of jun/AP-1 by E1A.

1991 • 50 citations

Two potentially oncogenic cyclins, cyclin A and cyclin D1, share common properties of subunit configuration, tyrosine phosphorylation and physical association with the Rb protein.

1993 • 49 citations

E1A dependent up-regulation of c-jun/AP-1 activity

1991 • 41 citations

The adenovirus E1A 289R and 243R proteins inhibit the phosphorylation of p300.

1994 • 40 citations

Characterization of conventional protein kinase C (PKC) isotype expression during F9 teratocarcinoma differentiation. Overexpression of PKC alpha alters the expression of some differentiation-dependent genes.

1994 • 39 citations

The Adenovirus Ela Gene Induces Differentiation of F9 Teratocarcinoma Cells

1987 • 32 citations

Retinoic acid-induced transition from protein kinase C beta to protein kinase C alpha in differentiated F9 cells: correlation with altered regulation of proto-oncogene expression by phorbol esters.

1996 • 23 citations

Adenovirus 12S E1A gene represses differentiation of F9 teratocarcinoma cells.

1990 • 22 citations

Altered AP-1/ATF complexes in adenovirus-E1-transformed cells due to EIA-dependent induction of ATF3.

1996 • 21 citations

The CR1 and CR3 domains of the adenovirus type 5 E1A proteins can independently mediate activation of ATF-2

1996 • 18 citations

A novel pathway for retinoic acid-induced differentiation of F9 cells that is distinct from receptor-mediatedTrans-activation

1994 • 16 citations

The adenovirus-5 12S E1a protein, but not the 13S induces expression of the endoA differentiation marker in F9 cells.

1989 • 14 citations