Cutting Edge: Inflammatory Signals Drive Organ-Specific Autoimmunity to Normally Cross-Tolerizing Endogenous Antigen

The Danger Model: A Renewed Sense of Self

2002 • 4,107 citations

The Immunology of Mucosal Models of Inflammation

2002 • 1,323 citations

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

1991 • 1,187 citations

Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo

1996 • 1,077 citations

A Discrete Subpopulation of Dendritic Cells Transports Apoptotic Intestinal Epithelial Cells to T Cell Areas of Mesenteric Lymph Nodes

2000 • 908 citations

Cross-Presentation, Dendritic Cells, Tolerance and Immunity

2001 • 894 citations

Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells

1997 • 719 citations

The enemy within: keeping self-reactive T cells at bay in the periphery

2002 • 586 citations

Identification of LFA-1 as a Candidate Autoantigen in Treatment-Resistant Lyme Arthritis

1998 • 514 citations

Vaccinia Virus Inhibits the Maturation of Human Dendritic Cells: A Novel Mechanism of Immune Evasion

1999 • 365 citations

Mechanisms for the induction of autoimmunity by infectious agents

2001 • 354 citations

Mechanisms for the induction of autoimmunity by infectious agents

2001 • 340 citations

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

1994 • 309 citations

Bystander Activation of Cytotoxic T Cells: Studies on the Mechanism and Evaluation of In Vivo Significance in a Transgenic Mouse Model

1997 • 176 citations

Antigen Concentration and Precursor Frequency Determine the Rate of CD8+ T Cell Tolerance to Peripherally Expressed Antigens

1999 • 174 citations

Viral and Bacterial Infections Interfere with Peripheral Tolerance Induction and Activate CD8+ T Cells to Cause Immunopathology

1998 • 161 citations

The role of viruses in Type I diabetes: two distinct cellular and molecular pathogenic mechanisms of virus-induced diabetes in animals

2001 • 151 citations

Viral Infection of Transgenic Mice Expressing a Viral Protein in Oligodendrocytes Leads to Chronic Central Nervous System Autoimmune Disease

1996 • 140 citations

Expression of Intestine-Specific Antigen Reveals Novel Pathways of CD8 T Cell Tolerance Induction

2000 • 138 citations

Experimental autoimmune encephalomyelitis in the rat: lessons in T‐cell immunology and autoreactivity

2001 • 134 citations

Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha.

1993 • 133 citations

Generation of mucosal cytotoxic T cells against soluble protein by tissue-specific environmental and costimulatory signals

1998 • 122 citations

Presented antigen from damaged pancreatic β cells activates autoreactive T cells in virus-mediated autoimmune diabetes

2002 • 121 citations

Presented antigen from damaged pancreatic β cells activates autoreactive T cells in virus-mediated autoimmune diabetes

2002 • 103 citations

Streptococcal M protein peptide with similarity to myosin induces CD4+ T cell-dependent myocarditis in MRL/++ mice and induces partial tolerance against coxsakieviral myocarditis.

1996 • 102 citations

Age-dependent intestinal lymphoproliferative disorder due to stem cell factor receptor deficiency: parameters in small and large intestine.

1997 • 69 citations

Flow cytometric and functional analyses of central nervous system-infiltrating cells in SJL/J mice with Theiler's virus-induced demyelinating disease. Evidence for a CD4+ T cell-mediated pathology.

1996 • 68 citations

CD40 Signaling Replaces CD4+ Lymphocytes and Its Blocking Prevents Chronic Rejection of Heart Transplants

2000 • 52 citations

Introduction: innate recognition of bacteria and protozoan parasites

2002 • 40 citations

Theiler's Virus‐Mediated Autoimmunity

2002 • 39 citations

CD40 Ligation in the Presence of Self-Reactive CD8 T Cells Leads to Severe Immunopathology

2002 • 24 citations