The role of viruses in Type I diabetes: two distinct cellular and molecular pathogenic mechanisms of virus-induced diabetes in animals

Insulin-Dependent Diabetes Mellitus

1996 • 1,171 citations

The Pathogenesis of Insulin-Dependent Diabetes Mellitus

1994 • 1,077 citations

HL-A ANTIGENS AND DIABETES MELLITUS

1974 • 802 citations

Molecular mimicry and immune‐mediated diseases

1998 • 592 citations

RUBELLA INFECTION AND DIABETES MELLITUS

1978 • 355 citations

ASSOCIATION OF CYTOMEGALOVIRUS INFECTION WITH AUTOIMMUNE TYPE 1 DIABETES

1988 • 316 citations

Diabetes Mellitus: Induction in Mice by Encephalomyocarditis Virus

1968 • 302 citations

A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles.

1989 • 260 citations

HLA-D and -DR antigens in genetic analysis of insulin dependent diabetes mellitus

1981 • 231 citations

COXSACKIE B, MUMPS, RUBELLA, AND CYTOMEGALOVIRUS SPECIFIC IgM RESPONSES IN PATIENTS WITH JUVENILE-ONSET INSULIN-DEPENDENT DIABETES MELLITUS IN BRITAIN, AUSTRIA, AND AUSTRALIA

1985 • 217 citations

Virus-induced diabetes mellitus. XVIII. Inhibition by a nondiabetogenic variant of encephalomyocarditis virus.

1980 • 199 citations

Virus-induced diabetes mellitus. XV. Beta cell damage and insulin-dependent hyperglycemia in mice infected with coxsackie virus B4.

1978 • 190 citations

Diabetes mellitus due to viruses ? some recent developments

1993 • 189 citations

Induction of Type I Diabetes by Kilham's Rat Virus in Diabetes-Resistant BB/Wor Rats

1991 • 180 citations

Congenital rubella syndrome as a model for Type 1 (insulin-dependent) diabetes mellitus: increased prevalence of islet cell surface antibodies

1984 • 156 citations

Persistent MHV (mouse hepatitis virus) infection reduces the incidence of diabetes mellitus in non-obese diabetic mice

1991 • 147 citations

Genetic and pathogenic basis of autoimmune diabetes in NOD mice

1994 • 136 citations

Virus-induced autoimmune disease

1996 • 130 citations

Virologic, immunologic, and genetic factors in insulin-dependent diabetes mellitus

1982 • 97 citations

Insulin-dependent diabetes mellitus as a β-cell targeted disease of immunoregulation

1995 • 91 citations

THE SEASONAL VARIATION IN THE ONSET OF ACUTE DIABETES

1926 • 89 citations

Kilham Rat Virus Triggers T-Cell–Dependent Autoimmune Diabetes in Multiple Strains of Rat

1996 • 89 citations

Relation of antecedent illness to development of diabetes in children.

1980 • 78 citations

Genomic differences between the diabetogenic and nondiabetogenic variants of encephalomyocarditis virus

1989 • 72 citations

[Myocarditis and insulitis following coxsackie virus infection].

1976 • 69 citations

Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins.

1996 • 67 citations

Genetic differences in susceptibility of pancreatic β cells to virus-induced diabetes mellitus

1976 • 63 citations

Evidence for a single locus controlling susceptibility to virus-induced diabetes mellitus

1978 • 61 citations

Possible role of macrophage-derived soluble mediators in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice

1997 • 60 citations

Role of viruses in type I diabetes

1998 • 60 citations

Long-term complications of virus-induced diabetes mellitus in mice

1982 • 57 citations

Beta cell expression of endogenous xenotropic retrovirus distinguishes diabetes-susceptible NOD/Lt from resistant NON/Lt mice.

1992 • 56 citations

Infection of peripancreatic lymph nodes but not islets precedes Kilham rat virus-induced diabetes in BB/Wor rats

1993 • 55 citations

Cellular and Molecular Mechanism for Kilham Rat Virus-Induced Autoimmune Diabetes in DR-BB Rats

2000 • 54 citations

Direct Involvement of Macrophages in Destruction of β-Cells Leading to Development of Diabetes in Virus-Infected Mice

1991 • 54 citations

Role of macrophages in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice

1990 • 51 citations

Islet cell DNA is a target of inflammatory attack by nitric oxide

1993 • 51 citations

Cytomegalovirus Infection Associated with Acute Pancreatitis, Rhabdomyolysis and Renal Failure.

1992 • 42 citations

Coxsackie virus B4 produces transient diabetes in nonhuman primates

1986 • 41 citations

An Incidence Peak of Juvenile Diabetes. Relation to Coxsackie B Virus Immune Response

1985 • 38 citations

Amino acid differences in capsid protein, VP1, between diabetogenic and nondiabetogenic variants of encephalomyocarditis virus

1988 • 37 citations

Gain or loss of diabetogenicity resulting from a single point mutation in recombinant encephalomyocarditis virus

1997 • 36 citations

Diabetes Mellitus in Cattle Infected with Bovine Viral Diarrhea Mucosal Disease Virus

1992 • 31 citations

A genetically determined host factor controlling susceptibility to encephalomyocarditis virus-induced diabetes in mice

1993 • 28 citations

Virus-induced diabetes mellitus. IV. Genetic and environmental factors influencing the development of diabetes after infection with the M variant of encephalomyocarditis virus

1976 • 27 citations

A practical approach to identification of susceptibility genes for IDDM

1992 • 26 citations

Determination of encephalomyocarditis viral diabetogenicity by a putative binding site of the viral capsid protein.

1998 • 23 citations

Transient diabetes following chicken pox.

1990 • 22 citations

Determination of diabetogenicity attributable to a single amino acid, Ala776, on the polyprotein of encephalomyocarditis virus

1993 • 21 citations

Retrovirus gag protein p30 in the islets of non-obese diabetic mice: relevance for pathogenesis of diabetes mellitus

1992 • 21 citations

Infection by Multiple Viruses and Lymphocyte Abnormalities at the Diagnosis of Diabetes

1988 • 20 citations

DNA fragmentation is an early event in cytokine-induced islet beta-cell destruction

1994 • 20 citations

[Acute onset of insulin-dependent diabetes mellitus caused by Epstein-Barr virus infection].

1985 • 18 citations

Development of a recombinant RNA technique for the construction of chimeric RNA with a long poly(C) tract

1993 • 10 citations

Insulin-Dependent Diabetes Mellitus

1992 • 8 citations

Differing attachment of diabetogenic and nondiabetogenic variants of encephalomyocarditis virus to beta-cells

1989 • 8 citations

Islet Cell Antibodies in Children with Mumps Infection

1987 • 5 citations