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Immunosuppressive effects of radiation on human dendritic cells: reduced IL-12 production on activation and impairment of naïve T-cell priming

Data up to Jan 2025

Published2005
Citations119
References43

Total Citations Per Year

Abstract

References (43)

Dendritic cells and the control of immunity

1998 • 14,345 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

Interleukin-12 and the regulation of innate resistance and adaptive immunity

2003 • 3,689 citations

Tolerogenic Dendritic Cells

2003 • 3,131 citations

Antigen Presentation and T Cell Stimulation by Dendritic Cells

2002 • 1,860 citations

Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability

1996 • 1,138 citations

Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells

1997 • 596 citations

Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells.

1998 • 524 citations

Dendritic Cell Vaccines for Cancer Immunotherapy

1999 • 497 citations

Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state.

2003 • 479 citations

Murine dendritic cells pulsed with whole tumor lysates mediate potent antitumor immune responsesin vitroandin vivo

1998 • 457 citations

Vascular Endothelial Growth Factor Affects Dendritic Cell Maturation Through the Inhibition of Nuclear Factor-κB Activation in Hemopoietic Progenitor Cells

1998 • 440 citations

Molecular and functional characteristics of dendritic cells generated from highly purified CD14+ peripheral blood monocytes.

1996 • 424 citations

Melanocyte Destruction after Antigen-Specific Immunotherapy of Melanoma

2000 • 423 citations

A Sense of Danger from Radiation1

2004 • 317 citations

How does radiation kill cells?

1999 • 313 citations

Generation of Mature Dendritic Cells from Human Blood

1997 • 297 citations

Coordinated events during bacteria-induced DC maturation

1999 • 219 citations

Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer.

1999 • 211 citations

Physical interaction between dendritic cells and tumor cells results in an immunogen that induces protective and therapeutic tumor rejection.

1998 • 179 citations

Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration.

2003 • 158 citations

Adoptive immunotherapy: Engineering T cell responses as biologic weapons for tumor mass destruction

2003 • 153 citations

CpG Oligodeoxynucleotide Enhances Tumor Response to Radiation

2004 • 146 citations

Isolation and expansion of cytomegalovirus-specific cytotoxic T lymphocytes to clinical scale from a single blood draw using dendritic cells and HLA-tetramers

2001 • 141 citations

Cutting Edge: Physical Interaction Between Dendritic Cells and Tumor Cells Results in an Immunogen That Induces Protective and Therapeutic Tumor Rejection

1998 • 141 citations

Nuclear localization of RelB is associated with effective antigen-presenting cell function.

1997 • 137 citations

Differential Induction of Interleukin-10 and Interleukin-12 in Dendritic Cells by Microbial Toll-Like Receptor Activators and Skewing of T-Cell Cytokine Profiles

2003 • 128 citations

Cytokine Dysregulation in Invasive Cervical Carcinoma and Other Human Neoplasias: Time to Consider the TH1/TH2 Paradigm

1998 • 119 citations

Ionizing Radiation Affects Human MART-1 Melanoma Antigen Processing and Presentation by Dendritic Cells

2004 • 114 citations

Alterations in human epidermal Langerhans cells by ultraviolet radiation: quantitative and morphological study

2003 • 112 citations

Dendritic cells stimulated with a bacterial product, OK-432, efficiently induce cytotoxic T lymphocytes specific to tumor rejection peptide.

2003 • 110 citations

Dendritic cell maturation is required for initiation of the immune response

1997 • 98 citations

NF-κB signaling pathway as a target for human tumor radiosensitization

2001 • 85 citations

Exposure to Ultraviolet Radiation Causes Dendritic Cells/Macrophages to Secrete Immune-Suppressive IL-12p40 Homodimers

2000 • 61 citations

Gamma irradiation of human dendritic cells influences proliferation and cytokine profile of T cells in autologous mixed lymphocyte reaction

2004 • 58 citations

The Th1-Th2 classification of cellular immune responses: concepts, current thinking and applications in haematological malignancy

2000 • 57 citations

Generation of Dendritic Cells from Peripheral Blood Adherent Cells in Medium with Human Serum

1998 • 49 citations

UVB-Irradiated Dendritic Cells Induce Nonproliferating, Regulatory Type T Cells

2002 • 34 citations

Melanoma-associated tumor antigens and their clinical relevance to immunotherapy.

1996 • 30 citations

Induction of tumor peptide-specific cytotoxic T cells under serum-free conditions by mature human dendritic cells

2000 • 29 citations

UVB-irradiated dendritic cells are impaired in their APC function and tolerize primed Th1 cells but not naive CD4+ T cells

2001 • 26 citations

Radiation-induced apoptosis

1998 • 16 citations

Dendritic Cells for the Immunotherapy of Cancer

2002 • 6 citations

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Immunosuppressive effects of radiation on human dendritic cells: reduced IL-12 production… (2005) – British Journal of Cancer | Metascience Observatory Explorer