Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma.

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes

1986 • 1,282 citations

Two TNF receptors

1992 • 1,048 citations

A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins

1990 • 977 citations

Molecular cloning and expression of a receptor for human tumor necrosis factor

1990 • 973 citations

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

1990 • 918 citations

An improved colorimetric assay for interleukin 2

1986 • 858 citations

The two different receptors for tumor necrosis factor mediate distinct cellular responses.

1991 • 815 citations

Tumor necrosis factor Characterization at the molecular, cellular and in vivo level

1991 • 708 citations

Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies.

1990 • 678 citations

Tumor necrosis factor.

1992 • 601 citations

Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.

1991 • 576 citations

Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response.

1989 • 461 citations

Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.

1990 • 396 citations

Two Different Cell Types have Different Major Receptors for Human Tumor Necrosis Factor (TNFα)

1989 • 368 citations

[Tumor necrosis factor].

1990 • 340 citations

Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences

1990 • 267 citations

Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor.

1990 • 263 citations

Interleukin 1 potentiates the lethal effect of tumor necrosis factor alpha/cachectin in mice.

1988 • 247 citations

Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses.

1990 • 215 citations

Expression of the types A and B tumor necrosis factor (TNF) receptors is independently regulated, and both receptors mediate activation of the transcription factor NF-kappa B. TNF alpha is not needed for induction of a biological effect via TNF receptors.

1990 • 207 citations

Binding and regulation of cellular functions by monoclonal antibodies against human tumor necrosis factor receptors.

1990 • 173 citations

A simple sensitive bioassay for interleukin-1 which is unresponsive to 103 U/ml of interleukin-2

1987 • 170 citations

Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines.

1988 • 164 citations

Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor.

1991 • 160 citations

Simple, sensitive and specific bioassay of interleukin-1

1989 • 159 citations

Both tumor necrosis factor receptor types mediate proliferative signals in human mononuclear cell activation.

1992 • 151 citations

Efficient transformation of mammalian cells with constructs containing a puromycin-resistance marker

1988 • 146 citations

Tumour necrosis factor is a compact trimer

1987 • 136 citations

Recombinant murine GM-CSF from E. coli has biological activity and is neutralized by a specific antiserum.

1985 • 121 citations

A rapid biologic assay for the detection of interleukin 1.

1983 • 117 citations

The Biology Of Cachectin/TNF: A Primary Mediator Of The Host Response

1989 • 115 citations

Localization of the active site of human tumour necrosis factor (hTNF) by mutational analysis.

1991 • 110 citations

Involvement of the 55- and 75-kDa tumor necrosis factor receptors in the generation of lymphokine-activated killer cell activity and proliferation of natural killer cells.

1991 • 105 citations

Tumor necrosis factor: receptors and inhibitors.

1991 • 90 citations

Hybrids between rat lymphoma and mouse T cells with inducible cytolytic activity

1982 • 81 citations

Independent regulation of 55‐kDa and 75‐kDa tumor necrosis factor receptors during activation of human peripheral blood B lymphocytes

1991 • 77 citations

Tumor necrosis factor-alpha as a proliferative signal for an IL-2-dependent T cell line: strict species specificity of action.

1989 • 74 citations

Characterization of the in vitro and in vivo species preference of human and murine tumor necrosis factor-alpha.

1988 • 64 citations

Molecular weight of recombinant human tumor necrosis factor-alpha.

1987 • 60 citations

Characterization of soluble factors that induce the cytolytic activity and the expression of T cell growth factor receptors of a T cell hybrid.

1984 • 54 citations

Four different interleukin-1 species sensitize to the lethal action of Tumour Necrosis Factor

1989 • 48 citations

Relationship between interleukin 1 (IL1), tumor necrosis factor (TNF) and a neutrophil attracting peptide (NAP-1)

1989 • 44 citations

A specific defect in CD3 gamma-chain gene transcription results in loss of T-cell receptor/CD3 expression late after human immunodeficiency virus infection of a CD4+ T-cell line.

1990 • 43 citations

Recombinant tumor necrosis factor can induce interleukin 2 receptor expression and cytolytic activity in a rat × mouse T cell hybrid

1987 • 40 citations

Structure of tumour necrosis factor by X-ray solution scattering and preliminary studies by single crystal X-ray diffraction

1988 • 39 citations

Lymphokines and Monokines in Anti-cancer Therapy

1986 • 36 citations

Molecular Cloning and Expression of the Type 1 and Type 2 Murine Receptors for Tumor Necrosis Factor

1991 • 36 citations

Species-specific TNF induction of thymocyte proliferation

1988 • 33 citations

Cloning, expression and cross‐linking analysis of the murine p55 tumor necrosis factor receptor

1991 • 28 citations

Development of a simple, sensitive and specific bioassay for interleukin-1 based on the proliferation of RPMI 1788 cells comparison with other bioassays for IL-1

1990 • 24 citations

Response of murine cell lines to an IL-1/IL-2-induced factor in a rat/mouse T hybridoma (PC60): differential induction of cytokines by human IL-1 alpha and IL-1 beta and partial amino acid sequence of rat GM-CSF.

1990 • 16 citations