Four different interleukin-1 species sensitize to the lethal action of Tumour Necrosis Factor

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

Biology of interleukin 1

1988 • 1,547 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

1989 • 1,183 citations

ASSOCIATION BETWEEN TUMOUR NECROSIS FACTOR IN SERUM AND FATAL OUTCOME IN PATIENTS WITH MENINGOCOCCAL DISEASE

1987 • 1,108 citations

Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.

1988 • 990 citations

Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice.

1987 • 560 citations

Interleukin 1 potentiates the lethal effect of tumor necrosis factor alpha/cachectin in mice.

1988 • 247 citations

Sensitization and desensitization to lethal effects of tumor necrosis factor and IL-1.

1988 • 179 citations

Recombinant tumor necrosis factor: Species specificity for a variety of human and murine transformed cell lines

1986 • 100 citations

Growing tumors induce hypersensitivity to endotoxin and tumor necrosis factor

1987 • 46 citations

Species specificity and involvement of other cytokines in endotoxic shock action of recombinant tumour necrosis factor in mice

1989 • 24 citations