Topography of Nicotinic Acetylcholine Receptor Membrane-embedded Domains

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Solute perturbation of protein fluorescence. Quenching of the tryptophyl fluorescence of model compounds and of lysozyme by iodide ion

1971 • 1,730 citations

Influence of proline residues on protein conformation

1991 • 1,125 citations

Acetylcholine receptor channel imaged in the open state

1995 • 1,002 citations

Nicotinic Acetylcholine Receptor an 9 Å Resolution

1993 • 822 citations

Structural homology of Torpedo californica acetylcholine receptor subunits

1983 • 798 citations

Lipid bilayer thickness varies linearly with acyl chain length in fluid phosphatidylcholine vesicles

1983 • 781 citations

Parallax method for direct measurement of membrane penetration depth utilizing fluorescence quenching by spin-labeled phospholipids

1987 • 671 citations

Functional domains of GABAA receptors

1995 • 485 citations

Allosteric Receptors after 30 Years

1998 • 430 citations

Large‐Scale Purification of the Acetylcholine‐Receptor Protein in Its Membrane‐Bound and Detergent‐Extracted Forms from Torpedo marmorata Electric Organ

1977 • 375 citations

Blocker protection in the pore of a voltage-gated K+ channel and its structural implications

2000 • 336 citations

Proline kinks in transmembrane α-helices

1991 • 327 citations

Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy.

1999 • 317 citations

Membrane Cholesterol Dynamics: Cholesterol Domains and Kinetic Pools

1991 • 262 citations

Intramolecular quenching of excited singlet states by stable nitroxyl radicals

1990 • 242 citations

The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex

1995 • 205 citations

Identifying the Lipid-Protein Interface of the Torpedo Nicotinic Acetylcholine Receptor: Secondary Structure Implications

1994 • 200 citations

Lipid-protein interactions in reconstituted membranes containing acetylcholine receptor

1983 • 189 citations

Immobilized lipid in acetylcholine receptor-rich membranes from Torpedo marmorata.

1978 • 182 citations

The 5-HT3 Receptor Channel

1995 • 180 citations

Identification of Acetylcholine Receptor Channel-Lining Residues in the M1 Segment of the .alpha.-Subunit

1995 • 179 citations

Mapping the lipid-exposed regions in the Torpedo californica nicotinic acetylcholine receptor

1992 • 141 citations

Location of ligand-binding sites on the nicotinic acetylcholine receptor alpha-subunit.

1986 • 119 citations

Membrane thickness and acyl chain length

1983 • 112 citations

Agonist-mediated changes of the acetylcholine receptor in its membrane environment

1978 • 104 citations

Improved Secondary Structure Predictions for a Nicotinic Receptor Subunit: Incorporation of Solvent Accessibility and Experimental Data into a Two-Dimensional Representation

1999 • 100 citations

Monitoring the permeability profile of lipid membranes with spin probes

1976 • 96 citations

Analysis of Protein and Peptide Penetration into Membranes by Depth-Dependent Fluorescence Quenching: Theoretical Considerations

1999 • 92 citations

Determination of the location of fluorescent probes attached to fatty acids using parallax analysis of fluorescence quenching: effect of carboxyl ionization state and environment on depth

1992 • 88 citations

Expression of fusion proteins of the nicotinic acetylcholine receptor from mammalian muscle identifies the membrane-spanning regions in the alpha and delta subunits.

1992 • 88 citations

Fourier Transform Infrared and Hydrogen/Deuterium Exchange Reveal an Exchange-resistant Core of α -Helical Peptide Hydrogens in the Nicotinic Acetylcholine Receptor

1995 • 84 citations

Secondary Structure Analysis of Individual Transmembrane Segments of the Nicotinic Acetylcholine Receptor by Circular Dichroism and Fourier Transform Infrared Spectroscopy

1998 • 79 citations

The hydrophobic photoreagent 3-(trifluoromethyl)-3-m-([125I] iodophenyl) diazirine is a novel noncompetitive antagonist of the nicotinic acetylcholine receptor.

1991 • 61 citations

THE TRANSVERSE LOCATION OF FLUOROPHORES IN LIPID BILAYERS AND MICELLES AS DETERMINED BY FLUORESCENCE QUENCHING TECHNIQUES

1984 • 45 citations

Spatial structure of the M3 transmembrane segment of the nicotinic acetylcholine receptor α subunit

1998 • 43 citations

A mixed helix—beta-sheet model of the transmembrane region of the nicotinic acetylcholine receptor

1996 • 42 citations

Effect of local anaesthetics on steroid-nicotinic acetylcholine receptor interactions in native membranes of Torpedo marmorata electric organ

1990 • 42 citations

Probing the Structure of the Nicotinic Acetylcholine Receptor with the Hydrophobic Photoreactive Probes [¹²⁵I]TID-BE and [¹²⁵I]TIDPC/16

1998 • 41 citations

The transverse location of the fluorescent probe trans-parinaric acid in lipid bilayers

1996 • 35 citations

1-Pyrene-butyrylcholine: a fluorescent probe for the cholinergic system.

1975 • 33 citations

Spatial structure of the M2 transmembrane segment of the nicotinic acetylcholine receptor α‐subunit

1999 • 30 citations

Protein-lipid interactions and Torpedo californica nicotinic acetylcholine receptor function. 1. Spatial disposition of cysteine residues in the .gamma. subunit analyzed by fluorescence-quenching and energy-transfer measurements

1993 • 23 citations

Covalent modification of a critical sulfhydryl group in the acetylcholine receptor: cysteine-222 of the .alpha.-subunit

1989 • 21 citations

Examining the Noncompetitive Antagonist-binding Site in the Ion Channel of the Nicotinic Acetylcholine Receptor in the Resting State

2000 • 20 citations

Localization of regions of the Torpedo californica nicotinic acetylcholine receptor labeled with an aryl azide derivative of phosphatidylserine

1991 • 17 citations

Topological Disposition of Cys 222 in the α-Subunit of Nicotinic Acetylcholine Receptor Analyzed by Fluorescence-Quenching and Electron Paramagnetic Resonance Measurements

1998 • 15 citations

Molecular Modeling of the Nicotinic Acetylcholine Receptor

1998 • 6 citations