Microsatellite instability is uncommon in breast cancer.

de la Chapelle, A.

1997 • 3,184 citations

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1993 • 2,282 citations

Genetic instability in colorectal cancers

1997 • 1,989 citations

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

1998 • 1,852 citations

MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY

1996 • 1,485 citations

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines.

1997 • 1,465 citations

Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator Phenotype

1997 • 1,329 citations

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 • 1,042 citations

Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

1996 • 957 citations

Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences.

1994 • 807 citations

Extracolonic cancer in hereditary nonpolyposis colorectal cancer

1993 • 690 citations

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

1995 • 653 citations

Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers

1998 • 629 citations

Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients.

1994 • 622 citations

Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome.

1993 • 596 citations

Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation

1994 • 496 citations

Mutations of GTBP in Genetically Unstable Cells

1995 • 471 citations

Microsatellite alterations as clonal markers for the detection of human cancer.

1994 • 448 citations

Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer.

1993 • 443 citations

Mismatch Repair, Genetic Stability, and Cancer

1994 • 429 citations

Instability of short tandem repeats (microsatellites) in human cancers

1994 • 413 citations

In vitro and in vivo resistance to cisplatin in cells that have lost DNA mismatch repair.

1997 • 275 citations

Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.

1996 • 236 citations

Tumor spectrum in cancer family syndrome (hereditary nonpolyposis colorectal cancer)

1991 • 199 citations

Microsatellite instability and loss of heterozygosity in breast cancer.

1994 • 189 citations

DNA chaperones: A solution to a persistence problem?

1994 • 168 citations

Microsatellite instability analysis: a multicenter study for reliability and quality control.

1997 • 166 citations

Genetic divergence in the clonal evolution of breast cancer.

1996 • 164 citations

The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of the endometrium, stomach, and colorectum.

1997 • 158 citations

Molecular genetic evidence of the occurrence of breast cancer as an integral tumor in patients with the hereditary nonpolyposis colorectal carcinoma syndrome

1996 • 145 citations

Comparative allelotype of in situ and invasive human breast cancer: high frequency of microsatellite instability in lobular breast carcinomas.

1995 • 141 citations

Microsatellite instability correlates with reduced survival and poor disease prognosis in breast cancer.

1996 • 134 citations

Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors.

1997 • 126 citations

Sporadic gastric carcinomas with microsatellite instability display a particular clinicopathologic profile

1995 • 124 citations

Genetic progression, histological grade, and allelic loss in ductal carcinoma in situ of the breast.

1996 • 105 citations

Allelic loss of chromosomal arm 8p in breast cancer progression.

1998 • 76 citations

Detection of frequent allelic loss of 6q23–q25.2 in microdissected human breast cancer tissues

1996 • 76 citations

Loss of DNA Mismatch Repair: Effects on the Rate of Mutation to Drug Resistance

1997 • 73 citations

Mutations of E2F-4 Trinucleotide Repeats in Colorectal Cancer with Microsatellite Instability

1996 • 70 citations

Microsatellite instability in early sporadic breast cancer

1996 • 66 citations

Microsatellite instability in sporadic human breast cancers

1996 • 57 citations

Microsatellite instability and pathological aspects of breast cancer

1995 • 54 citations

Microsatellite Instability and Loss of Heterozygosity in Primary Breast Tumours

1997 • 48 citations

Microsatellite instability in human cancer.

1995 • 39 citations

Microsatellite instability at a single locus (D11S988) on chromosome 11p15.5 as a late event in mammary tumorigenesis

1995 • 26 citations

Microsatellite instability in in situ and invasive sporadic breast cancers of Japanese women

1996 • 24 citations

Cellular Characterization and Retroviral Transduction of Short-Term Breast Cancer Cells

1995 • 3 citations