Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1993 • 2,282 citations

The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

1991 • 2,142 citations

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

1994 • 2,071 citations

Mutation of a mutL Homolog in Hereditary Colon Cancer

1994 • 1,834 citations

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

1994 • 1,544 citations

The Molecular Basis of Turcot's Syndrome

1995 • 1,116 citations

Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review

1993 • 1,076 citations

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 • 1,042 citations

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

1995 • 824 citations

Purification of DNA from formaldehyde fixed and paraffin embedded human tissue

1985 • 821 citations

Allelic Loss of Chromosome 18q and Prognosis in Colorectal Cancer

1994 • 708 citations

Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients.

1994 • 622 citations

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 • 599 citations

Molecular Diagnosis of Familial Adenomatous Polyposis

1993 • 588 citations

GTBP, a 160-Kilodalton Protein Essential for Mismatch-binding Activity in Human Cells

1995 • 528 citations

HEREDITY WITH REFERENCE TO CARCINOMA

1913 • 501 citations

Mutations of GTBP in Genetically Unstable Cells

1995 • 471 citations

Malignant tumors of the central nervous system associated with familial polyposis of the colon

1959 • 471 citations

Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer

1993 • 434 citations

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.

1995 • 403 citations

Genetic instability occurs in the majority of young patients with colorectal cancer

1995 • 378 citations

hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds.

1994 • 366 citations

Founding mutations and Alu-mediated recombination in hereditary colon cancer

1995 • 308 citations

Protein truncation test (PTT) for rapid detection of translation-terminating mutations

1993 • 297 citations

Hereditary with reference to carcinoma as shown by the study of the cases examined in a pathological laboratory of the University of Michigan, 1895-1913

1913 • 295 citations

MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in Yeast

1994 • 287 citations

Microsatellite instability in Muir-Torre syndrome.

1994 • 180 citations

Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage.

1994 • 146 citations

Close linkage to chromosome 3p and conservation of ancestral founding haplotype in hereditary nonpolyposis colorectal cancer families.

1994 • 96 citations

Genetic linkage in Muir-Torre syndrome to the same chromosomal region as cancer family syndrome

1994 • 76 citations

Monoallelic mutation analysis (MAMA) for identifying germline mutations

1995 • 56 citations