Prostaglandin E2 modulates dendritic cell function via EP2 and EP4 receptor subtypes
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References (55)
Immunobiology of Dendritic Cells
2000 • 6,653 citations
Secretory products of macrophages.
1987 • 2,670 citations
International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.
1994 • 1,729 citations
Prostaglandin synthase 2
1996 • 1,212 citations
Comprehensive medicinal chemistry
1991 • 1,195 citations
Pro‐inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum‐free conditions
1997 • 1,179 citations
Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin-producing suppressor cell.
1977 • 797 citations
Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes
2001 • 733 citations
Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes
2001 • 692 citations
Prostaglandin endoperoxide synthase: regulation of enzyme expression
1991 • 642 citations
Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment
1991 • 580 citations
Macrophages synthesise and release prostaglandins in response to inflammatory stimuli
1977 • 573 citations
Prostaglandins modulate macrophage Ia expression
1982 • 545 citations
Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells
2002 • 498 citations
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype.
1993 • 475 citations
Prostaglandin and thromboxane biosynthesis
1991 • 444 citations
Prostaglandin E inhibits the production of human interleukin 2.
1982 • 423 citations
Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo.
1996 • 415 citations
Molecular mechanisms of diverse actions of prostanoid receptors
1995 • 390 citations
Cyclooxygenase-2-Issued Prostaglandin E2 Enhances the Production of Endogenous IL-10, Which Down-Regulates Dendritic Cell Functions
2002 • 388 citations
Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor.
1993 • 381 citations
Prostaglandin E2 Induces the Final Maturation of IL-12-Deficient CD1a+CD83+ Dendritic Cells: The Levels of IL-12 Are Determined During the Final Dendritic Cell Maturation and Are Resistant to Further Modulation
1998 • 379 citations
Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E2 regulates the migratory capacity of specific DC subsets
2002 • 369 citations
Prostaglandin E2 acts at two distinct pathways of T lymphocyte activation: inhibition of interleukin 2 production and down-regulation of transferrin receptor expression.
1985 • 311 citations
Receptors for prostaglandin E2 that regulate cellular immune responses in the mouse
2001 • 287 citations
Role of the Parasite-Derived Prostaglandin D2 in the Inhibition of Epidermal Langerhans Cell Migration during Schistosomiasis Infection
2001 • 273 citations
Receptors for prostaglandin E2 that regulate cellular immune responses in the mouse
2001 • 271 citations
Thromboxane, Prostaglandin and Leukotriene Receptors
1989 • 258 citations
Nuclear localization of prostaglandin E 2 receptors
1998 • 240 citations
Platelet-activating Factor, a Molecular Sensor for Cellular Damage, Activates Systemic Immune Suppression
2002 • 234 citations
Localization of Functional Prostaglandin E2 Receptors EP3 and EP4 in the Nuclear Envelope
1999 • 227 citations
Bacterial lipopolysaccharides prime macrophages for enhanced release of arachidonic acid metabolites.
1986 • 211 citations
Cyclic adenosine monophosphate-responsive elements are involved in the transcriptional activation of the human IL-10 gene in monocytic cells
1999 • 161 citations
Prostaglandin E2 receptors of the EP2 and EP4 subtypes regulate activation and differentiation of mouse B lymphocytes to IgE-secreting cells.
1996 • 155 citations
The mouse prostaglandin E receptor EP2 subtype: cloning, expression, and Northern blot analysis
1995 • 155 citations
Prostanoid and leukotriene receptors: a progress report from the IUPHAR working parties on classification and nomenclature.
1995 • 150 citations
Regulation of monokine gene expression: prostaglandin E2 suppresses tumor necrosis factor but not interleukin-1 alpha or beta-mRNA and cell-associated bioactivity.
1989 • 149 citations
Prostaglandin E2 Stimulates IL-8 Gene Expression in Human Colonic Epithelial Cells by a Posttranscriptional Mechanism
1998 • 147 citations
Leukotriene B4 enhances interleukin-6 (IL-6) production and IL-6 messenger RNA accumulation in human monocytes in vitro: transcriptional and posttranscriptional mechanisms
1992 • 127 citations
Regulation of Monokine Gene Expression: Prostaglandin E2 Suppresses Tumor Necrosis Factor but Not Interleukin-1α or β-mRNA and Cell-Associated Bioactivity
1989 • 115 citations
The Expression of Prostaglandin E Receptors EP2 and EP4 and Their Different Regulation by Lipopolysaccharide in C3H/HeN Peritoneal Macrophages
2001 • 115 citations
cAMP-elevating agents suppress dendritic cell function
2001 • 109 citations
Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E2 inhibits lipopolysaccharide‐induced tumour necrosis factor‐α generation
1997 • 106 citations
Dendritic Cells Issued in Vitro from Bone Marrow Produce PGE2 That Contributes to the Immunomodulation Induced by Antigen-Presenting Cells
2001 • 103 citations
Sensitivity Difference to the Suppressive Effect of Prostaglandin E2 Among Mouse Strains: A Possible Mechanism to Polarize Th2 Type Response in BALB/c Mice
2000 • 99 citations
Analysis of the defects responsible for the impaired regulation of EBV-induced B cell proliferation by rheumatoid arthritis lymphocytes. II. Role of monocytes and the increased sensitivity of rheumatoid arthritis lymphocytes to prostaglandin E.
1983 • 98 citations
Cyclooxygenase-2 Expression in Lipopolysaccharide-Stimulated Human Monocytes Is Modulated by Cyclic AMP, Prostaglandin E2, and Nonsteroidal Anti-inflammatory Drugs
2000 • 86 citations
Prostaglandins Inhibit 5-Lipoxygenase-Activating Protein Expression and Leukotriene B4 Production from Dendritic Cells Via an IL-10-Dependent Mechanism
2003 • 83 citations
Molecular aspects of the structures and functions of the prostaglandin E receptors
1996 • 72 citations
A molecular analysis of PGE receptor (EP) expression on normal and transformed B lymphocytes: Coexpression of EP1, EP2, EP3β and EP4
1996 • 57 citations
Dendritic cells produce eicosanoids, which modulate generation and functions of antigen-presenting cells
2002 • 45 citations
Effect of COX-2 inhibitor NS-398 on expression of PGE2receptor subtypes in M-1 mouse CCD cells
2001 • 37 citations
Chapter 14. Prostanoid receptors and signal transduction
1996 • 31 citations
Characterization and Regulation of Prostaglandin E2 Receptors on Normal and Malignant Murine B Lymphocytes
1995 • 25 citations
IN VITRO GENERATION OF HELPER T CELLS AND SUPPRESSOR T CELLS THAT REGULATE THE CYTOLYTIC T LYMPHOCYTE RESPONSE TO TRINITROPHENYL-MODIFIED SYNGENEIC CELLS
1982 • 6 citations