Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E₂ inhibits lipopolysaccharide‐induced tumour necrosis factor‐α generation

International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.

1994 • 1,729 citations

Pharmacologic Analysis of Drug Receptor Interaction

1988 • 936 citations

Cloning and expression of cDNA for a human thromboxane A2 receptor

1991 • 680 citations

Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

1993 • 546 citations

Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype.

1993 • 475 citations

Cloning and expression of a cDNA for the human prostanoid FP receptor.

1994 • 386 citations

Regulation of tumor necrosis factor production by adrenaline and beta-adrenergic agonists.

1992 • 385 citations

Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype.

1994 • 384 citations

Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor.

1993 • 381 citations

Molecular Cloning and Characterization of the Human Prostanoid DP Receptor

1995 • 332 citations

Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.

1993 • 305 citations

Studies of the characterisation of prostanoid receptors: A proposed classification

1982 • 305 citations

A novel inhibitory prostanoid receptor in piglet saphenous vein

1994 • 273 citations

Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype.

1994 • 244 citations

Cloning and expression of a cDNA for the human prostanoid IP receptor.

1994 • 187 citations

Prostaglandin E receptor subtypes in smooth muscle: agonist activities of stable prostacyclin analogues

1986 • 167 citations

Characterization of receptors involved in the direct and indirect actions of prostaglandins E and I on the guinea‐pig ileum

1992 • 154 citations

Prostanoid receptors — the development of a working classification

1984 • 150 citations

Characterization of prostanoid relaxant/inhibitory receptors (ψ) using a highly selective agonist, TR4979

1986 • 149 citations

Cloning and Expression of the EP2 Subtype of Human Receptors for Prostaglandin E2

1993 • 144 citations

Quantifying Proliferation of Cultured Human and Rabbit Airway Smooth Muscle Cells in Response to Serum and Platelet-derived Growth Factor

1992 • 138 citations

Identification of prostaglandin E receptor ‘EP2’ cloned from mastocytoma cells as EP4 subtype

1995 • 137 citations

Characterization of cAMP-dependent inhibition of LPS-induced TNFα production by rolipram, a specific phosphodiesterase IV (PDE IV) inhibitor

1994 • 136 citations

Regulation of cyclic AMP metabolism in rabbit cortical collecting tubule cells by prostaglandins.

1988 • 132 citations

Molecular cloning and expression of multiple isoforms of human prostaglandin E receptor EP3 subtype generated by alternative messenger RNA splicing: multiple second messenger systems and tissue-specific distributions.

1995 • 129 citations

Suppression of lipopolysaccharide-induced tumor necrosis factor-alpha generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase.

1995 • 129 citations

Isoforms of the EP3 Subtype of Human Prostaglandin E2 Receptor Transduce Both Intracellular Calcium and cAMP Signals

1994 • 122 citations

Regulation of tumor necrosis factor expression in a macrophage-like cell line by lipopolysaccharide and cyclic AMP

1989 • 121 citations

Ligand binding to thromboxane receptors on human platelets: correlation with biological activity

1983 • 111 citations

Focus on prostacyclin and its novel mimetics

1996 • 109 citations

6-isopropoxy-9-oxoxanthene-2-carboxylic acid (AH 6809), a human EP2 receptor antagonist

1995 • 108 citations

Prostacyclin analogs suppress the synthesis of tumor necrosis factor-α in LPS-stimulated human peripheral blood mononuclear cells

1993 • 102 citations

Molecular cloning and expression of human EP₃ receptors: evidence of three variants with differing carboxyl termini

1994 • 100 citations

Potent contractile actions of prostanoid EP₃‐receptor agonists on human isolated pulmonary artery

1994 • 92 citations

AH6809, a prostaglandin DP‐receptor blocking drug on human platelets

1988 • 90 citations

Investigation of the prostaglandin E (EP‐) receptor subtype mediating relaxation of the rabbit jugular vein

1992 • 87 citations

New evidence with selective agonists and antagonists for the subclassification of PGE2-sensitive (EP) receptors.

1987 • 85 citations

Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids

1995 • 80 citations

Cloning and Expression of the EP3-Subtype of Human Receptors for Prostaglandin E2

1994 • 75 citations

Pharmacological profile of a novel carbacyclin derivative with high metabolic stability and oral activity in the rat

1986 • 73 citations

Cloning and expression of a prostaglandin E receptor EP3 subtype from human erythroleukaemia cells

1994 • 65 citations

A molecular analysis of PGE receptor (EP) expression on normal and transformed B lymphocytes: Coexpression of EP1, EP2, EP3β and EP4

1996 • 57 citations

Pharmacological studies on prostanoid receptors in the rabbit isolated saphenous vein: a comparison with the rabbit isolated ear artery

1996 • 56 citations

AH13205, A Selective Prostanoid EP₂‐receptor Agonist

1993 • 50 citations

Prostanoid-induced inhibition of lipolysis in rat isolated adipocytes: Probable involvement of EP3 receptors

1992 • 47 citations

Modulation of noradrenaline release from the sympathetic nerves of the human saphenous vein and pulmonary artery by presynaptic EP₃‐ and DP‐receptors

1994 • 40 citations

Exclusive expression of the Gs‐linked prostaglandin E₂ receptor subtype 4 mRNA in human mononuclear Jurkat and KM‐3 cells and coexpression of subtype 4 and 2 mRNA in U‐937 cells

1996 • 40 citations

Effects of prostacyclin analogs on the synthesis of tissue factor, tumor necrosis factor-alpha and interleukin-1 beta in human monocytic THP-1 cells.

1994 • 32 citations

Prejunctional prostanoid receptors on cardiac adrenergic terminals belong to the EP₃ subtype

1991 • 29 citations

Characterization of prostanoid receptors on rat neutrophils

1994 • 29 citations

Characterization of the prostaglandin E₂ sensitive (EP)‐receptor in the rat isolated trachea

1994 • 28 citations

Independent down-regulation of EP2 and EP3 subtypes of the prostaglandin E2 receptors on U937 human monocytic cells.

1995 • 28 citations

Characterization of the prostanoid receptors mediating inhibition of PAF‐induced aggregation of guinea‐pig eosinophils

1997 • 24 citations

An EP receptor with a novel pharmacological profile in the T‐cell line Jurkat

1995 • 24 citations

Comparison of the EP receptor subtypes mediating relaxation of the rabbit jugular and pig saphenous veins

1995 • 23 citations

Prostaglandin E₂ Receptors on Human Peripheral Blood Monocytes

1985 • 23 citations

Cicaprost and the type IV phosphodiesterase inhibitor, rolipram, synergize in suppression of tumor necrosis factor-α synthesis

1996 • 17 citations

Characterization of prostaglandin E2 receptors expressed on human monocytic leukaemic cell line, U937

1993 • 11 citations

Characterization of Thromboxane Receptors in Human Platelets

1985 • 10 citations