Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Apoptosis by Death Factor

1997 • 5,038 citations

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1997 • 3,167 citations

Control of apoptosis and mitotic spindle checkpoint by survivin

1998 • 1,881 citations

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

1998 • 1,243 citations

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

1995 • 728 citations

Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer.

1998 • 720 citations

Growth factors in development, transformation, and tumorigenesis

1991 • 695 citations

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

1996 • 637 citations

Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

1999 • 613 citations

A Single BIR Domain of XIAP Sufficient for Inhibiting Caspases

1998 • 611 citations

Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria

1994 • 577 citations

Expression of survivin and its relationship to loss of apoptosis in breast carcinomas

2000 • 561 citations

Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation.

1998 • 512 citations

A Novel Anti-Apoptosis Gene: Re-expression of Survivin Messenger RNA as a Prognosis Marker in Non–Small-Cell Lung Cancers

1999 • 498 citations

A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy.

2000 • 491 citations

Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas.

1998 • 473 citations

Induction of Apoptosis and Inhibition of Cell Proliferation bysurvivin Gene Targeting

1998 • 413 citations

Survivin promotes cell proliferation in human hepatocellular carcinoma

2000 • 329 citations

Inhibition of melanoma tumor growth in vivo by survivin targeting

2001 • 290 citations

Survivin as a Radioresistance Factor in Pancreatic Cancer

2000 • 202 citations

Expression of the apoptosis inhibitor, survivin, in nonmelanoma skin cancer and gene targeting in a keratinocyte cell line.

1999 • 167 citations

Apoptosis in the genesis and prevention of cancer.

1992 • 101 citations

Molecular basis of spontaneous regression of neuroblastoma: role of neurotrophic signals and genetic abnormalities.

1998 • 90 citations

Xa receptor EPR‐1

1995 • 86 citations

Gene therapy for malignant gliomas using replication incompetent retroviral and adenoviral vectors encoding the cytochrome P450 2B1 gene together with cyclophosphamide.

1996 • 53 citations

Enhanced sensitivity to tumor growth and development in multistage skin carcinogenesis by transforming growth factor-α-induced epidermal growth factor receptor activation but not p53 inactivation

1997 • 17 citations