Immunity to MurineChlamydia trachomatisGenital Tract Reinfection Involves B Cells and CD4⁺T Cells but Not CD8⁺T Cells

Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis

1998 • 1,548 citations

Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis

1981 • 1,054 citations

CD8+ T Cell Effector Mechanisms in Resistance to Infection

2000 • 725 citations

Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways.

1997 • 365 citations

Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection

1995 • 333 citations

CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract

1995 • 263 citations

A mAb recognizing a surface antigen ofMycobacterium tuberculosisenhances host survival

1998 • 261 citations

Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice

1997 • 254 citations

Protective monoclonal antibodies recognize epitopes located on the major outer membrane protein of Chlamydia trachomatis.

1987 • 253 citations

Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor-deficient mice despite a strong local immunoglobulin A response

1997 • 204 citations

Chlamydia Inhibits Interferon γ–inducible Major Histocompatibility Complex Class II Expression by Degradation of Upstream Stimulatory Factor 1

1999 • 200 citations

Degradation of Transcription Factor Rfx5 during the Inhibition of Both Constitutive and Interferon γ–Inducible Major Histocompatibility Complex Class I Expression in Chlamydia-Infected Cells

2000 • 199 citations

Chlamydia trachomatis genital tract infection of antibody-deficient gene knockout mice

1997 • 195 citations

Correlation of host immune response with quantitative recovery of Chlamydia trachomatis from the human endocervix

1983 • 187 citations

Protective efficacy of major outer membrane protein-specific immunoglobulin A (IgA) and IgG monoclonal antibodies in a murine model of Chlamydia trachomatis genital tract infection

1995 • 168 citations

Protective cytotoxic T lymphocytes are induced during murine infection with Chlamydia trachomatis.

1994 • 167 citations

Resolution of murine chlamydial genital infection by the adoptive transfer of a biovar-specific, Th1 lymphocyte clone.

1993 • 166 citations

Cutting Edge: Role of B Lymphocytes in Protective Immunity AgainstSalmonella typhimuriumInfection

2000 • 163 citations

Role of NK Cells in Early Host Response to Chlamydial Genital Infection

1998 • 142 citations

Gene Knockout B Cell-Deficient Mice Demonstrate That B Cells Play an Important Role in the Initiation of T Cell Responses toChlamydia trachomatis(Mouse Pneumonitis) Lung Infection

1998 • 139 citations

Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis

1995 • 139 citations

Cutting Edge: Paradigm Revisited: Antibody Provides Resistance toListeriaInfection

1999 • 136 citations

Protective cytotoxic T lymphocytes are induced during murine infection with Chlamydia trachomatis.

1994 • 126 citations

Role for CD8+ T cells in antichlamydial immunity defined by Chlamydia-specific T-lymphocyte clones

1994 • 119 citations

Differential sensitivity of distinct Chlamydia trachomatis isolates to IFN-gamma-mediated inhibition.

1999 • 117 citations

Antibody-mediated protection against intracellular pathogens

1998 • 117 citations

Antibody-dependent cell-mediated antibacterial activity of intestinal lymphocytes with secretory IgA

1983 • 113 citations

In Situ Analysis of the Evolution of the Primary Immune Response in MurineChlamydia trachomatisGenital Tract Infection

2000 • 113 citations

Protective monoclonal antibodies to Chlamydia trachomatis serovar- and serogroup-specific major outer membrane protein determinants

1989 • 108 citations

Humoral immunity in the resolution of genital infection in female guinea pigs infected with the agent of guinea pig inclusion conjunctivitis

1979 • 108 citations

Importance of B cells, but Not Specific Antibodies, in Primary and Secondary Protective Immunity to the Intracellular BacteriumFrancisella tularensisLive Vaccine Strain

1999 • 106 citations

Chlamydial Infection in Inducible Nitric Oxide Synthase Knockout Mice

1998 • 103 citations

Gamma Interferon Production by Cytotoxic T Lymphocytes Is Required for Resolution ofChlamydia trachomatisInfection

1998 • 101 citations

The Effect of Doxycycline Treatment on the Development of Protective Immunity in a Murine Model of Chlamydial Genital Infection

1999 • 94 citations

Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chalamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge

1997 • 93 citations

Differential Sensitivity of Distinct Chlamydia trachomatis Isolates to IFN-γ-Mediated Inhibition

1999 • 92 citations

Identification and characterization of T helper cell epitopes of the major outer membrane protein of Chlamydia trachomatis.

1990 • 91 citations

Humoral and cellular immunity in secondary infection due to murine Chlamydia trachomatis

1997 • 89 citations

CD8+ T lymphocyte-mediated lysis of Chlamydia-infected L cells using an endogenous antigen pathway.

1994 • 83 citations

IgA-driven T cell-mediated anti-bacterial immunity in man after live oral Ty 21a vaccine.

1986 • 78 citations

Induction of HLA Class I-Restricted CD8+ CTLs Specific for the Major Outer Membrane Protein of Chlamydia trachomatis in Human Genital Tract Infections

1999 • 73 citations

Protective role of serum antibody in immunity to chlamydial genital infection

1989 • 72 citations

Synovial T lymphocyte–specific immune response to Chlamydia trachomatis in Reiter's disease

1991 • 70 citations

Humoral Immune Response in Acquired Immunity to Chlamydial Genital Infection of Female Guinea Pigs

1983 • 67 citations

IgA-dependent cell-mediated activity against enteropathogenic bacteria: distribution, specificity, and characterization of the effector cells.

1984 • 65 citations

Clearance ofChlamydia trachomatisfrom the Murine Genital Mucosa Does Not Require Perforin-Mediated Cytolysis or Fas-Mediated Apoptosis

1999 • 61 citations

Accumulation of chlamydial lipopolysaccharide antigen in the plasma membranes of infected cells

1989 • 61 citations

Localization of chlamydial group Antigen in McCoy cell monolayers infected with Chlamydia trachomatis or Chlamydia psittaci

1981 • 61 citations

B‐cell‐deficient mice develop complete immune protection against genital tract infection with Chlamydia trachomatis

1997 • 60 citations

Role of L3T4-bearing T-cell populations in experimental murine chlamydial salpingitis

1991 • 54 citations

Reactivation of chlamydial genital tract infection in mice

1997 • 50 citations

Inducible Nitric Oxide Synthase Does Not Affect Resolution of Murine Chlamydial Genital Tract Infections or Eradication of Chlamydiae in Primary Murine Cell Culture

1998 • 47 citations

Neither Interleukin-6 nor Inducible Nitric Oxide Synthase Is Required for Clearance ofChlamydia trachomatisfrom the Murine Genital Tract Epithelium

1998 • 45 citations

The Role of B Cells in the Establishment of T Cell Response in Mice Infected with an Intracellular Bacteria, Listeria monocytogenes

1999 • 43 citations

Natural anti-bacterial activity against Salmonella typhi by human T4+ lymphocytes armed with IgA antibodies.

1985 • 43 citations

Murine cytotoxic T lymphocytes induced following Chlamydia trachomatis intraperitoneal or genital tract infection respond to cells infected with multiple serovars

1995 • 41 citations

Immunogenicity of a synthetic oligopeptide corresponding to antigenically common T-helper and B-cell neutralizing epitopes of the major outer membrane protein of Chlamydia trachomatis

1993 • 37 citations

Poliovirus hybrids expressing neutralization epitopes from variable domains I and IV of the major outer membrane protein of Chlamydia trachomatis elicit broadly cross-reactive C. trachomatis-neutralizing antibodies

1995 • 31 citations

Cytotoxic-T-lymphocyte-mediated cytolysis of L cells persistently infected with Chlamydia spp

1996 • 30 citations

Examination of chlamydial glycolipid with monoclonal antibodies: cellular distribution and epitope binding.

1991 • 26 citations

Examination of chlamydial glycolipid with monoclonal antibodies: cellular distribution and epitope binding.

1991 • 3 citations