Chlamydial Infection in Inducible Nitric Oxide Synthase Knockout Mice

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

NITRIC OXIDE AND MACROPHAGE FUNCTION

1997 • 4,106 citations

CELLULAR RESPONSES TO INTERFERON-γ

1997 • 2,885 citations

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

1995 • 1,454 citations

Altered immune responses in mice lacking inducible nitric oxide synthase

1995 • 1,296 citations

Inflammation, immunoregulation, and inducible nitric oxide synthase

1993 • 877 citations

Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine.

1990 • 573 citations

Inducible Nitric Oxide Is Essential for Host Control of Persistent but Not Acute Infection with the Intracellular Pathogen Toxoplasma gondii

1997 • 432 citations

Induction of tryptophan catabolism is the mechanism for gamma-interferon-mediated inhibition of intracellular Chlamydia psittaci replication in T24 cells

1986 • 389 citations

Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways.

1997 • 365 citations

Detection of Chlamydia pneumoniae in aortic lesions of atherosclerosis by immunocytochemical stain.

1993 • 348 citations

Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice

1997 • 254 citations

Nitric oxide: Cytokine-regulation of nitric oxide in host resistance to intracellular pathogens

1994 • 230 citations

Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor-deficient mice despite a strong local immunoglobulin A response

1997 • 204 citations

Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages

1989 • 201 citations

Resolution of chlamydial genital infection in B-cell-deficient mice and immunity to reinfection

1988 • 175 citations

Protective cytotoxic T lymphocytes are induced during murine infection with Chlamydia trachomatis.

1994 • 167 citations

Resolution of murine chlamydial genital infection by the adoptive transfer of a biovar-specific, Th1 lymphocyte clone.

1993 • 166 citations

Regulation of transferrin receptor expression and ferritin content in human mononuclear phagocytes. Coordinate upregulation by iron transferrin and downregulation by interferon gamma.

1993 • 150 citations

Inhibition of growth of Chlamydia trachomatis by human gamma interferon

1985 • 135 citations

Resolution of chlamydial genital infection with antigen-specific T-lymphocyte lines

1991 • 135 citations

Protective cytotoxic T lymphocytes are induced during murine infection with Chlamydia trachomatis.

1994 • 126 citations

Effect of gamma interferon on resolution of murine chlamydial genital infection

1992 • 122 citations

Role for CD8+ T cells in antichlamydial immunity defined by Chlamydia-specific T-lymphocyte clones

1994 • 119 citations

Antiparasitic and antiproliferative effects of indoleamine 2,3-dioxygenase enzyme expression in human fibroblasts

1994 • 118 citations

Pathogenesis of pelvic inflammatory disease.

1993 • 117 citations

Pathogenesis of Pelvic Inflammatory Disease

1991 • 108 citations

The diverse habitats of obligate intracellular parasites

1998 • 80 citations

Lymphokine-mediated inhibition of Chlamydia replication in mouse fibroblasts is neutralized by anti-gamma interferon immunoglobulin

1983 • 79 citations

Humoral immune response to chlamydial genital infection of mice with the agent of mouse pneumonitis

1989 • 73 citations

Biology of Leishmania and leishmaniasis.

1985 • 68 citations

Cellular immune response during uncomplicated genital infection with Chlamydia trachomatis in humans

1981 • 64 citations

The molecular mechanism of T-cell control of Chlamydia in mice: role of nitric oxide.

1996 • 61 citations

Role of endogenous gamma interferon in host defense against Chlamydia trachomatis infections

1989 • 58 citations

Nitric oxide production: a mechanism ofChlamydia trachomatisinhibition in interferon-γ-treated RAW264.7 cells

1996 • 56 citations

Overview of Chlamydia trachomatis Infection and the Requirements for a Vaccine

1985 • 53 citations

Molecular mechanism of T‐cell control of Chlamydia in mice: role of nitric oxide in vivo

1996 • 53 citations

Interferon-γ in the diagnosis and pathogenesis of pelvic inflammatory disease

1989 • 47 citations

Integrin-mediated epithelial-T cell interaction enhances nitric oxide production and increased intracellular inhibition of Chlamydia

1996 • 46 citations

Neither Interleukin-6 nor Inducible Nitric Oxide Synthase Is Required for Clearance ofChlamydia trachomatisfrom the Murine Genital Tract Epithelium

1998 • 45 citations

Inhibition of Intracellular Multiplication of Human Strains ofChlamydia trachomatisby Nitric Oxide

1997 • 35 citations

Interactions between macrophages and chlamydiae.

1994 • 26 citations

Antiparasitic effects of nitric oxide in an in vitro murine model of Chlamydia trachomatis infection and an in vivo murine model of Leishmania major infection.

1994 • 25 citations

Reinfection of the mouse genital tract with Chlamydia trachomatis: the relationship of antibody to immunity.

1984 • 12 citations