STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation

STATs in oncogenesis

2000 • 1,723 citations

Regulation of JAK–STAT signalling in the immune system

2003 • 1,313 citations

The role of STATs in transcriptional control and their impact on cellular function

2000 • 1,186 citations

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

2002 • 1,160 citations

Stat proteins and oncogenesis

2002 • 776 citations

Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes

2004 • 566 citations

Quantitative Gene Expression Analysis in Microdissected Archival Formalin-Fixed and Paraffin-Embedded Tumor Tissue

2001 • 490 citations

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target

2005 • 431 citations

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

2002 • 421 citations

Persistent STAT3 Activation in Colon Cancer Is Associated with Enhanced Cell Proliferation and Tumor Growth

2005 • 397 citations

Novel Roles of Unphosphorylated STAT3 in Oncogenesis and Transcriptional Regulation

2005 • 392 citations

Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells

2005 • 285 citations

Activated Signal Transducer and Activator of Transcription (STAT) 3

2004 • 252 citations

Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer

2003 • 244 citations

Activation Pattern of Signal Transducers and Activators of Transcription (STAT) Factors in Inflammatory Bowel Diseases

2005 • 221 citations

Constitutive Activation of JAK3/STAT3 in Colon Carcinoma Tumors and Cell Lines

2005 • 206 citations

Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis.

2003 • 194 citations

Roles and Regulation of Stat Family Transcription Factors in Human Breast Cancer

2004 • 192 citations

Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors

2005 • 171 citations

Increased Expression of the Interleukin-11 Receptor and Evidence of STAT3 Activation in Prostate Carcinoma

2001 • 151 citations

A Novel Platinum Compound Inhibits Constitutive Stat3 Signaling and Induces Cell Cycle Arrest and Apoptosis of Malignant Cells

2005 • 151 citations

Phosphorylation State-Specific Antibodies

2003 • 150 citations

Down-Regulation of Signal Transducer and Activator of Transcription 3 Expression Using Vector-Based Small Interfering RNAs Suppresses Growth of Human Prostate Tumor In vivo

2005 • 128 citations

Nucleocytoplasmic shuttling of STAT transcription factors

2004 • 124 citations

New and Old Functions of STAT3: A Pivitol Target for Individualized Treatment of Cancer

2005 • 116 citations

Constitutive activation of Stat3 signaling pathway in human colorectal carcinoma

2004 • 113 citations

Analysis of Signal Transducer and Activator of Transcription 3 (Stat 3) Pathway in Multiple Myeloma

2003 • 94 citations

Stat proteins and oncogenesis

2002 • 82 citations

The Role of Signal Transducer and Activator of Transcription Factors in Leukemogenesis

2004 • 67 citations

Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors—correlation to tumor histopathology and clinical follow-up

2005 • 37 citations

Centrosome-, chromosomal-passenger- and cell-cycle-associated mRNAs are differentially regulated in the development of sporadic colorectal cancer

2006 • 29 citations