Gene regulatory networks in lactation: identification of global principles using bioinformatics

The Universal Protein Resource (UniProt)

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Bioinformatics and Computational Biology Solutions Using R and Bioconductor

2005 • 3,212 citations

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases.

1999 • 2,168 citations

MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data

2003 • 865 citations

Analyzing gene expression data in terms of gene sets: methodological issues

2007 • 795 citations

Pajek— Analysis and Visualization of Large Networks

2002 • 683 citations

Ensembl 2007

2006 • 622 citations

Online Predicted Human Interaction Database

2005 • 608 citations

Levels of Hypoxia-Inducible Factor-1 During Breast Carcinogenesis

2001 • 586 citations

The Universal Protein Resource (UniProt)

2006 • 576 citations

Graph Drawing Software

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Information networks in the mammary gland

2005 • 486 citations

Prolactin-mediated transcriptional and post-transcriptional control of casein gene expression

1979 • 476 citations

An atlas of mouse mammary gland development.

2000 • 398 citations

Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3

2003 • 364 citations

Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis!

2007 • 354 citations

Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression

2003 • 328 citations

The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x

2007 • 311 citations

Mammary epithelial cell: Influence of extracellular matrix composition and organization during development and tumorigenesis

2007 • 300 citations

Physiological functions of protein kinase B/Akt

2004 • 287 citations

Activation of Akt (Protein Kinase B) in Mammary Epithelium Provides a Critical Cell Survival Signal Required for Tumor Progression

2001 • 281 citations

Yeast two-hybrid contributions to interactome mapping

2006 • 242 citations

Multiple Testing Procedures: the multtest Package and Applications to Genomics

2005 • 231 citations

Functional Development of the Mammary Gland: Use of Expression Profiling and Trajectory Clustering to Reveal Changes in Gene Expression During Pregnancy, Lactation, and Involution

2003 • 202 citations

Vascular remodelling during the normal and malignant life cycle of the mammary gland

2001 • 173 citations

Mammary Gland Involution Is Delayed by Activated Akt in Transgenic Mice

2001 • 165 citations

Mammary Gland Involution as a Multi-step Process

2007 • 163 citations

Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev

1999 • 157 citations

Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation

2003 • 139 citations

Functional Microarray Analysis of Mammary Organogenesis Reveals a Developmental Role in Adaptive Thermogenesis

2002 • 123 citations

Roles of the Innate Immune System in Mammary Gland Remodeling During Involution

2007 • 113 citations

Delayed mammary gland involution in MMTV-AKT1 transgenic mice

2002 • 90 citations

LOCATE: a mouse protein subcellular localization database

2005 • 89 citations

HIF1α is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland

2003 • 82 citations

Role of amino acids in translational mechanisms governing milk protein synthesis in murine and ruminant mammary epithelial cells

2006 • 77 citations

CoPub Mapper: mining MEDLINE based on search term co-publication

2005 • 76 citations

Epithelial transcytosis of immunoglobulins.

1998 • 73 citations

Microarray Analysis of the Involution Switch

2003 • 70 citations

Insulin and Prolactin Synergistically Stimulate β-Casein Messenger Ribonucleic Acid Translation by Cytoplasmic Polyadenylation

2004 • 67 citations

ANALYSIS AND VISUALIZATION OF LARGE NETWORKS

2003 • 62 citations

Secretory activation in the mammary gland: it's not just about milk protein synthesis!

2007 • 61 citations

Global properties of biological networks

2005 • 55 citations

Albumin transcytosis across the epithelium of the lactating mouse mammary gland

2004 • 55 citations

Molecular regulation of milk trace mineral homeostasis

2005 • 55 citations

Analysis of Lactation Defects in Transgenic Mice

2006 • 52 citations

A novel function for Sam68: Enhancement of HIV-1 RNA 3′ end processing

2004 • 48 citations

Transferrin and prolactin transcytosis in the lactating mammary epithelial cell.

1998 • 48 citations

Understanding Milk's Bioactive Components: A Goal for the Genomics Toolbox

2004 • 43 citations

The Declining Phase of Lactation: Peripheral or Central, Programmed or Pathological?

2007 • 31 citations

Decreased expression of β₁‐integrin and focal adhesion kinase in epithelial cells may initiate involution of mammary glands

2004 • 30 citations

Cloning of Bovine Eukaryotic Translation Initiation Factor 4E (eIF-4E) and Its Expression in the Bovine Mammary Gland at Different Physiological Stages

2001 • 8 citations

Deleted Work

1955 • 0 citations